Management problems in patients with pancreatic cancer from a surgeon's perspective

Pancreatic cancer is one of the most lethal gastrointestinal tumor entities. Surgery is the only chance for cure; however, only a minority of patients can be offered this option. Due to the anatomic location of the gland, tumor-related problems and complications affecting the surrounding structures are common, leading to biliary and gastric outlet obstruction as well as portal vein thrombosis. This review article summarizes the management of pancreatic cancer-related problems from a surgical point of view. We further describe surgical treatment options in unresectable, metastasized and recurring pancreatic cancer, highlighting potential resection of oligometastatic disease in selected settings. (c) 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )

Automated summary

Pancreatic cancer is a deadly gastrointestinal tumor, with surgery being the only chance for cure. This review article discusses the surgical management of pancreatic cancer-related problems and treatment options for unresectable, metastasized, and recurring cases, including potential resection of oligometastatic disease in certain situations.