相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
Philipp Schommers et al.
CELL (2020)
HIV persists throughout deep tissues with repopulation from multiple anatomical sources
Antoine Chaillon et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
A Bispecific Antibody That Simultaneously Recognizes the V2-and V3-Glycan Epitopes of the HIV-1 Envelope Glycoprotein Is Broader and More Potent than Its Parental Antibodies
Meredith E. Davis-Gardner et al.
MBIO (2020)
Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention
Kathryn E. Stephenson et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38 (2020)
VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA
Manxue Jia et al.
CELL HOST & MICROBE (2020)
Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies
Thach H. Chu et al.
PLOS PATHOGENS (2020)
Antibody-Dependent Cellular Phagocytosis of HIV-1-Infected Cells Is Efficiently Triggered by IgA Targeting HIV-1 Envelope Subunit gp41
Maxence Duchemin et al.
FRONTIERS IN IMMUNOLOGY (2020)
Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression
Jose M. Martinez-Navio et al.
IMMUNITY (2019)
Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial
Frances H. Priddy et al.
LANCET HIV (2019)
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
Till Schoofs et al.
IMMUNITY (2019)
Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial
Trevor A. Crowell et al.
LANCET HIV (2019)
A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge
Amarendra Pegu et al.
CELL HOST & MICROBE (2019)
Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates
Reda Rawi et al.
SCIENTIFIC REPORTS (2019)
Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial
Martin R. Gaudinski et al.
LANCET HIV (2019)
Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques
Matthew S. Parsons et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Establishment of a Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent Reservoirs
Nina C. Flerin et al.
JOURNAL OF VIROLOGY (2019)
IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody
Simone I. Richardson et al.
PLOS PATHOGENS (2019)
Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir
Wen-Han Yu et al.
JCI INSIGHT (2019)
Anti-HIV IgM protects against mucosal SHIV transmission
Siqi Gong et al.
AIDS (2018)
Short Communication: Protective Efficacy of Broadly Neutralizing Antibody PGDM1400 Against HIV-1 Challenge in Humanized Mice
Yme U. van der Velden et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2018)
Tandem bispecific neutralizing antibody eliminates HIV-1 infection in humanized mice
Xilin Wu et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry
Salar N. Khan et al.
JOURNAL OF VIROLOGY (2018)
The less-is-more in therapeutic antibodies: Afucosylated anti-cancer antibodies with enhanced antibody-dependent cellular cytotoxicity
Natasha A. Pereira et al.
MABS (2018)
Humanized mouse models to study pathophysiology and treatment of HIV infection
Guillemette Masse-Ranson et al.
CURRENT OPINION IN HIV AND AIDS (2018)
Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults
Martin R. Gaudinski et al.
PLOS MEDICINE (2018)
Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117
Yehuda Z. Cohen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Combination therapy with anti-HIV-1 antibodies maintains viral suppression
Pilar Mendoza et al.
NATURE (2018)
Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals
Yotam Bar-On et al.
NATURE MEDICINE (2018)
Phase 3 Study of Ibalizumab for Multidrug-Resistant HIV-1
Brinda Emu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys
Erica N. Borducchi et al.
NATURE (2018)
Recent progress in broadly neutralizing antibodies to HIV
Devin Sok et al.
NATURE IMMUNOLOGY (2018)
Immunoglobulin A: magic bullet or Trojan horse?
Marieke H. Heineke et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2017)
Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys
Boris Julg et al.
JOURNAL OF VIROLOGY (2017)
Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys
Boris Julg et al.
JOURNAL OF VIROLOGY (2017)
Potent In Vivo NK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein
Ariola Bardhi et al.
JOURNAL OF VIROLOGY (2017)
Antibody 10-1074 suppresses viremia in HIV-1-infected individuals
Marina Caskey et al.
NATURE MEDICINE (2017)
Probing the compartmentalization of HIV-1 in the central nervous system through its neutralization properties
Karl Stefic et al.
PLOS ONE (2017)
Modulating IgG effector function by Fc glycan engineering
Tiezheng Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
Ling Xu et al.
SCIENCE (2017)
Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection
Matthew S. Parsons et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller
Natalia T. Freund et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time
Anna Hake et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
VRC01 antibody protects against vaginal and rectal transmission of human immunodeficiency virus 1 in hu-BLT mice
Ming Sun et al.
ARCHIVES OF VIROLOGY (2016)
Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency
Stylianos Bournazos et al.
CELL (2016)
Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity
Yaoxing Huang et al.
CELL (2016)
Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
Jinghe Huang et al.
IMMUNITY (2016)
Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo
Maud Deruaz et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa
Alysia A. Ahmed et al.
JOURNAL OF STRUCTURAL BIOLOGY (2016)
Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design
Young D. Kwon et al.
JOURNAL OF VIROLOGY (2016)
Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies
Marco Thomann et al.
MOLECULAR IMMUNOLOGY (2016)
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
Johannes F. Scheid et al.
NATURE (2016)
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
Rajeev Gautam et al.
NATURE (2016)
Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption
K. J. Bar et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo
Ching-Lan Lu et al.
SCIENCE (2016)
Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus
Jinyan Liu et al.
SCIENCE (2016)
Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences
Lawrence J. Tartaglia et al.
PLOS PATHOGENS (2016)
Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C
Kshitij Wagh et al.
PLOS PATHOGENS (2016)
Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults
J. E. Ledgerwood et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2015)
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
Marina Caskey et al.
NATURE (2015)
HIV reservoirs as obstacles and opportunities for an HIV cure
Tae-Wook Chun et al.
NATURE IMMUNOLOGY (2015)
Antibody responses to envelope glycoproteins in HIV-1 infection
Dennis R. Burton et al.
NATURE IMMUNOLOGY (2015)
Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
Rebecca M. Lynch et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Generation and Evaluation of Clade C Simian-Human Immunodeficiency Virus Challenge Stocks
Hui-Wen Chang et al.
JOURNAL OF VIROLOGY (2015)
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function
Amy W. Chung et al.
AIDS (2014)
Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity
Stylianos Bournazos et al.
CELL (2014)
Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
Ariel Halper-Stromberg et al.
CELL (2014)
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
Florian Klein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
Masashi Shingai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
Rebecca S. Rudicell et al.
JOURNAL OF VIROLOGY (2014)
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
C. Moog et al.
MUCOSAL IMMUNOLOGY (2014)
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
Sung-Youl Ko et al.
NATURE (2014)
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Nicole A. Doria-Rose et al.
NATURE (2014)
Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission
Alejandro B. Balazs et al.
NATURE MEDICINE (2014)
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
Devin Sok et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor
Amarendra Pegu et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice
Cheryl A. Stoddart et al.
VIROLOGY (2014)
Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission
Jennifer D. Watkins et al.
AIDS (2013)
Neutralizing Polyclonal IgG Present during Acute Infection Prevents Rapid Disease Onset in Simian-Human Immunodeficiency Virus SHIVSF162P3-Infected Infant Rhesus Macaques
J. Pablo Jaworski et al.
JOURNAL OF VIROLOGY (2013)
Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia
Masashi Shingai et al.
NATURE (2013)
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
Dan H. Barouch et al.
NATURE (2013)
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
Joshua A. Horwitz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cervicovaginal HIV-1-neutralizing immunoglobulin A detected among HIV-1-exposed seronegative female partners in HIV-1-discordant couples
Robert Y. Choi et al.
AIDS (2012)
Marketing approval of mogamulizumab A triumph for glyco-engineering
Alain Beck et al.
MABS (2012)
Antibody-based protection against HIV infection by vectored immunoprophylaxis
Alejandro B. Balazs et al.
NATURE (2012)
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
Jinghe Huang et al.
NATURE (2012)
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
Florian Klein et al.
NATURE (2012)
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
Brian Moldt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
Hugo Mouquet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Antibody-Dependent Cell-Mediated Cytotoxicity in Simian Immunodeficiency Virus-Infected Rhesus Monkeys
Yue Sun et al.
JOURNAL OF VIROLOGY (2011)
Antibody-Dependent Cell-Mediated Viral Inhibition Emerges after Simian Immunodeficiency Virus SIVmac251 Infection of Rhesus Monkeys Coincident with gp140-Binding Antibodies and Is Effective against Neutralization-Resistant Viruses
Mohammed Asmal et al.
JOURNAL OF VIROLOGY (2011)
Broad neutralization coverage of HIV by multiple highly potent antibodies
Laura M. Walker et al.
NATURE (2011)
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
Johannes F. Scheid et al.
SCIENCE (2011)
Complement and its role in innate and adaptive immune responses
Jason R. Dunkelberger et al.
CELL RESEARCH (2010)
Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
Xueling Wu et al.
SCIENCE (2010)
IgM in microbial infections: Taken for granted?
Rachael Racine et al.
IMMUNOLOGY LETTERS (2009)
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
Johannes F. Scheid et al.
NATURE (2009)
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
Ann J. Hessell et al.
NATURE MEDICINE (2009)
Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
Laura M. Walker et al.
SCIENCE (2009)
Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
Ann J. Hessell et al.
PLOS PATHOGENS (2009)
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers
Taha Hirbod et al.
AIDS (2008)
Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection
Saurabh Mehandru et al.
JOURNAL OF VIROLOGY (2007)
Fc receptor but not complement binding is important in antibody protection against HIV
Ann J. Hessell et al.
NATURE (2007)
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
A Trkola et al.
NATURE MEDICINE (2005)
Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12
C Armbruster et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2004)
A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1
C Armbruster et al.
AIDS (2002)
High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR
RL Shields et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140
A Trkola et al.
JOURNAL OF VIROLOGY (2001)
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
JR Mascola et al.
NATURE MEDICINE (2000)
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
TW Baba et al.
NATURE MEDICINE (2000)