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Ana Herrero et al.
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Adrienne D. Cox et al.
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K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif
Frederick D. Tsai et al.
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Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9
Bing Yu et al.
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The Differential Palmitoylation States of N-Ras and H-Ras Determine Their Distinct Golgi Subcompartment Localizations
Stephen J. Lynch et al.
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Methionine oxidation and reduction in proteins
Geumsoo Kim et al.
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Synthesis of 2′,3′,4′-trihydroxyflavone (2-D08), an inhibitor of protein sumoylation
Yeong Sang Kim et al.
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Sheila Piva et al.
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Drugging the undruggable RAS: Mission Possible?
Adrienne D. Cox et al.
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Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities
Vivien Landre et al.
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Taoling Zeng et al.
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Shirish Shukla et al.
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W. Chien et al.
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Nadia Dani et al.
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Proteasome inhibitors in acute leukemia
Denise Niewerth et al.
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Rachael Baker et al.
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HDAC6 and SIRT2 Regulate the Acetylation State and Oncogenic Activity of Mutant K-RAS
Moon Hee Yang et al.
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Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors
Pamela J. Sung et al.
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A Comprehensive Survey of Ras Mutations in Cancer
Ian A. Prior et al.
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Michael Steckel et al.
CELL RESEARCH (2012)
BubR1 Is Modified by Sumoylation during Mitotic Progression
Feikun Yang et al.
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Competition between Sumoylation and Ubiquitination of Serine Hydroxymethyltransferase 1 Determines Its Nuclear Localization and Its Accumulation in the Nucleus
Donald D. Anderson et al.
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Feikun Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Regulating the regulator: post-translational modification of RAS
Ian M. Ahearn et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Sensitization of Human Pancreatic Cancer Cells Harboring Mutated K-ras to Apoptosis
Ling Shen et al.
PLOS ONE (2012)
Regulation of RAS oncogenicity by acetylation
Moon Hee Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome
Youmna Kfoury et al.
BLOOD (2011)
The EMT regulator slug and lung carcinogenesis
Jin-Yuan Shih et al.
CARCINOGENESIS (2011)
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins
Maria Sideridou et al.
JOURNAL OF CELL BIOLOGY (2011)
Redox Proteomics of Protein-bound Methionine Oxidation
Bart Ghesquiere et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Ubiquitination of K-Ras Enhances Activation and Facilitates Binding to Select Downstream Effectors
Atsuo T. Sasaki et al.
SCIENCE SIGNALING (2011)
Rabex-5 Ubiquitin Ligase Activity Restricts Ras Signaling to Establish Pathway Homeostasis in Drosophila
Hua Yan et al.
CURRENT BIOLOGY (2010)
Feedback Regulation of Ras Signaling by Rabex-5-Mediated Ubiquitination
Lizhong Xu et al.
CURRENT BIOLOGY (2010)
Post-translational modification by SUMO
Zara Hannoun et al.
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PIAS proteins: pleiotropic interactors associated with SUMO
Miia M. Rytinki et al.
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H-Ras is degraded by Wnt/β-catenin signaling via β-TrCP-mediated polyubiquitylation
Sung-Eun Kim et al.
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Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors
Andrea Bertolotti-Ciarlet et al.
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Ras acylation, compartmentalization and signaling nanoclusters (Review)
Yoav I. Henis et al.
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Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα
Meelad M. Dawlaty et al.
CELL (2008)
Sumoylating and desumoylating enzymes at nuclear pores: underpinning their unexpected duties?
Benoit Palancade et al.
TRENDS IN CELL BIOLOGY (2008)
PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription
J. J. Palvimo
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Deregulated overexpression of hCdtl and hCdc6 promotes malignant Behavior
Michalis Liontos et al.
CANCER RESEARCH (2007)
SUMO-specific proteases and the cell cycle - An essential role for SENP5 in cell proliferation
Alessandra Di Bacco et al.
CELL CYCLE (2006)
Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity
Kimberly W. Raines et al.
BIOCHEMICAL JOURNAL (2006)
Ras, PI(3)K and mTOR signalling controls tumour cell growth
Reuben J. Shaw et al.
NATURE (2006)
Differential modification of Ras proteins by ubiquitination
N Jura et al.
MOLECULAR CELL (2006)
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
TG Bivona et al.
MOLECULAR CELL (2006)
Postprenylation CAAX processing is required for proper localization of ras but not rho GTPases
D Michaelson et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange
JG Williams et al.
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Dnmt3b, de novo DNA methyltransferase, interacts with SUMO-1 and Ubc9 through its N-terminal region and is subject to modification by SUMO-1
ES Kang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9
T Buschmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Ras and Rho GTPases: A family reunion
D Bar-Sagi et al.
CELL (2000)
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