Add-Ons for Assisted Reproductive Technology: Do Patients Get Honest Information from Fertility Clinics' Websites?

Add-on procedures are actively promoted on some fertility clinic websites as proven means to improve IVF success rates, especially for couples with repeated implantation/IVF failures. However, the actual contribution of these interventions to live birth rates remains inconclusive. At present, little is known about the type and quality of the information provided on the IVF clinics' websites regarding the merits of add-ons. A systematic evaluation of the quality of information on add-on procedures in fertility clinic websites was performed using 10-criteria structured questionnaire. We included English language websites that presented in the search engine after typing the following key-words:endometrial scratching(ES), intralipid infusions(ILI), assisted hatching(AHA), PGT-A, or PGS. In total, 254 websites were evaluated. In most cases, an accurate description of the add-on procedures was provided (78.8%). However, only a minority (12%) reported their undetermined effectiveness. The use of PGT-A was more often encouraged (52.8%) than ES (23.6%) and AHA (16%). The cost was infrequently presented (6.9%). Scientific references were only rarely provided for ILI, versus 12.7% for ES, 4.0% for AHA, and 5.6% for PGT-A. The information entry date was often missing. None of the websites reported the clinic's pregnancy-rate following the add-on procedures. Information on add-ons available to patients from IVF clinic websites is often inaccurate. This could perpetuate false myths among infertile patients about these procedures and raises concern regarding possible commercial bias. It is imperative that IVF clinic websites will better communicate the associated risks and uncertainties of add-ons to prospective patients.

Automated summary

Add-on procedures in fertility clinics are promoted as means to improve IVF success rates, but their actual contribution to live birth rates remains inconclusive. The accuracy and quality of information provided on these procedures on IVF clinics' websites are lacking, raising concerns about potential commercial bias and misinformation among infertile patients.