4.5 Article

Bi(OTf)3-Catalysed Access to 2,3-Substituted Isoindolinones and Tricyclic N,O-Acetals by Trapping of Bis-N-Acyliminium Species in a Tandem Process

期刊

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2016, 期 21, 页码 3592-3602

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201600530

关键词

Homogeneous catalysis; Domino reactions; Bismuth; Carbocations; Nitrogen heterocycles; Oxygen heterocycles

资金

  1. Campus France
  2. Service of Cooperation and Cultural Action (SCAC) of the French Embassy in Mauritania
  3. Centre National de la Recherche Scientifique (CNRS)
  4. Labex SynOrg
  5. CRIAAN computer center at Normandie Univ.

向作者/读者索取更多资源

New 1,3-bis-N-acyliminium species generated easily with nontoxic Bi(OTf)(3) catalyst at very low loadings (2 mol-%) were trapped inter- and intramolecularly with various poly-nucleophiles. This mild, efficient, practical and general tandem approach provides an array of substituted isoindolinones and cyclic N,O-acetals.

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