4.8 Article

PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biology

Brain endothelial cell TRPA1 channels initiate neurovascular coupling

Pratish Thakore et al.

Summary: Cerebral blood flow is dynamically regulated by neurovascular coupling to meet the brain's metabolic demands. TRPA1 channels in capillary endothelial cells act as neural activity sensors, initiating microvascular vasodilatory responses to redirect blood flow to regions of metabolic demand.
Article Endocrinology & Metabolism

Estrogen deficiency induces memory loss via altered hippocampal HB-EGF and autophagy

Rukmani Pandey et al.

JOURNAL OF ENDOCRINOLOGY (2020)

Review Neurosciences

Neuronal regulation of the blood-brain barrier and neurovascular coupling

Luke Kaplan et al.

NATURE REVIEWS NEUROSCIENCE (2020)

Article Multidisciplinary Sciences

The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K plus -mediated neurovascular communication

Arash Moshkforoush et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

PIP2: A critical regulator of vascular ion channels hiding in plain sight

Osama F. Harraz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Cell Biology

HB-EGF depolarizes hippocampal arterioles to restore myogenic tone in a genetic model of small vessel disease

Jackson T. Fontaine et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2020)

Review Clinical Neurology

Small vessel disease: mechanisms and clinical implications

Joanna M. Wardlaw et al.

LANCET NEUROLOGY (2019)

Article Cardiac & Cardiovascular Systems

Vascular Cognitive Impairment and Dementia

Costantino Iadecola et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Article Neurosciences

Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Rikesh M. Rajani et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)

Article Clinical Neurology

CADASIL brain vessels show a HTRA1 loss-of-function profile

Andreas Zellner et al.

ACTA NEUROPATHOLOGICA (2018)

Review Biochemistry & Molecular Biology

Phospholipid subcellular localization and dynamics

Yanbo Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Hematology

The yin and yang of KV channels in cerebral small vessel pathologies

Masayo Koide et al.

MICROCIRCULATION (2018)

Article Multidisciplinary Sciences

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion

Osama F. Harraz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Clinical Neurology

Altered dynamics of neurovascular coupling in CADASIL

Clement Huneau et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2018)

Article Clinical Neurology

RVCL-S and CADASIL display distinct impaired vascular function

Irene de Boer et al.

NEUROLOGY (2018)

Review Endocrinology & Metabolism

The vascular basement membrane in the healthy and pathological brain

Maj S. Thomsen et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)

Article Clinical Neurology

Reducing Timp3 or Vitronectin Ameliorates Disease Manifestations in CADASIL Mice

Carmen Capone et al.

ANNALS OF NEUROLOGY (2016)

Review Biochemistry & Molecular Biology

Phosphoinositides regulate ion channels

Bertil Hille et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)

Article Multidisciplinary Sciences

Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease

Fabrice Dabertrand et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Universal Approach to FRAP Analysis of Arbitrary Bleaching Patterns

Daniel Blumenthal et al.

SCIENTIFIC REPORTS (2015)

Review Biochemistry & Molecular Biology

Understanding Metabolic Regulation and Its Influence on Cell Physiology

Christian M. Metallo et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

Scott B. Hansen et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

Phospholipase C-γ1 is required for the epidermal growth factor receptor-induced squamous cell carcinoma cell mitogenesis

Zhongjian Xie et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Multidisciplinary Sciences

Pericytes regulate the blood-brain barrier

Annika Armulik et al.

NATURE (2010)

Article Cardiac & Cardiovascular Systems

Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis

Prabhakara Reddy Nagareddy et al.

CARDIOVASCULAR RESEARCH (2009)

Review Clinical Neurology

CADASIL

Hugues Chabriat et al.

LANCET NEUROLOGY (2009)

Review Cell Biology

Phosphatidylinositol 4-kinases: old enzymes with emerging functions

Andras Balla et al.

TRENDS IN CELL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Features of selective kinase inhibitors

ZA Knight et al.

CHEMISTRY & BIOLOGY (2005)

Article Oncology

HB-EGF is a potent inducer of tumor growth and angiogenesis

PP Ongusaha et al.

CANCER RESEARCH (2004)