4.8 Article

Life-course trajectories of body mass index from adolescence to old age: Racial and educational disparities

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NATL ACAD SCIENCES
DOI: 10.1073/pnas.2020167118

关键词

body mass index; obesity; life course; age trajectory; social disparities

资金

  1. NIH [R01 AG057800, P01 HD31921, T32 HD007168, T32 HD091058, R24 HD050924]
  2. University Cancer Research Funds
  3. Eunice Kennedy Shriver National Institute of Child Health and Human Development [P01 HD31921]

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This study found that with more recent birth cohorts, there are higher levels of BMI and larger increases in BMI with age. Disparities in BMI between Black and Hispanic individuals compared to Whites were present early in life and persisted at all ages. Higher parental and adulthood education levels were associated with lower levels of BMI, and disparities in BMI trajectories were larger for women compared to men.
No research exists on how body mass index (BMI) changes with age over the full life span and social disparities therein. This study aims to fill the gap using an innovative life-course research design and analytic methods to model BMI trajectories from early adolescence to old age across 20th-century birth cohorts and test sociodemographic variation in such trajectories. We conducted the pooled integrative data analysis (IDA) to combine data from four national population-based NIH longitudinal cohort studies that collectively cover multiple stages of the life course (Add Health, MIDUS, ACL, and HRS) and estimate mixed-effects models of age trajectories of BMI for men and women. We examined associations of BMI trajectories with birth cohort, race/ethnicity, parental education, and adult educational attainment. We found higher mean levels of and larger increases in BMI with age across more recent birth cohorts as compared with earlier-born cohorts. Black and Hispanic excesses in BMI compared with Whites were present early in life and persisted at all ages, and, in the case of Black? White disparities, were of larger magnitude for more recent cohorts. Higher parental and adulthood educational attainment were associated with lower levels of BMI at all ages. Women with college-educated parents also experienced less cohort increase in mean BMI. Both race and education disparities in BMI trajectories were larger for women compared with men.

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