4.8 Article

Mitochondrial ATP synthase subunit d, a component of the peripheral stalk, is essential for growth and heat stress tolerance in Arabidopsis thaliana

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Complexome profiling reveals novel insights into the composition and assembly of the mitochondrial ATP synthase of Arabidopsis thaliana

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Summary: The mitochondrial ATP synthase, responsible for producing the energy needed for eucaryotic life, is structurally similar across species but exhibits some variations in plant-specific subunits. While assembly of this enzyme has been extensively studied in bacteria, yeast, and mammals, little is known about its assembly in plants. Through complexome profiling, researchers have identified assembly intermediates and proposed a model for the assembly pathway of plant mitochondria's ATP synthase, revealing that plant-specific subunits are also present in other organisms. This study demonstrates that the subunit composition and assembly pathway of plant mitochondria's ATP synthase are largely conserved with other mitochondrial enzymes.

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