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Angiotensin Receptor Blockers Are Not Just for Hypertension Anymore

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PHYSIOLOGY
卷 36, 期 3, 页码 160-173

出版社

AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00036.2020

关键词

angiotensin receptor blockers; COVID-19; estrogen; inflammation; neuroprotection

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In addition to controlling blood pressure, angiotensin receptor blockers also reduce inflammation and protect various organ functions, making them useful in treating inflammatory, age-related, neurodegenerative, and metabolic disorders.
Beyond blood pressure control, angiotensin receptor blockers reduce common injury mechanisms, decreasing excessive inflammation and protecting endothelial and mitochondrial function, insulin sensitivity, the coagulation cascade, immune responses, cerebrovascular flow, and cognition, properties useful to treat inflammatory, age-related, neurodegenerative, and metabolic disorders of many organs including brain and lung.

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