4.7 Review

Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Misaponin B Induces G2/M Arrest, Cytokinesis Failure and Impairs Autophagy

Gunho Won et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Article Medicine, Research & Experimental

Liriopesides B induces apoptosis and cell cycle arrest in human non-small cell lung cancer cells

Hongxu Sheng et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)

Article Pharmacology & Pharmacy

Paris saponin II-induced paraptosis-associated cell death increased the sensitivity of cisplatin

Shuli Man et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Autophagy in Human Health and Disease: Novel Therapeutic Opportunities

Francesca Giampieri et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Editorial Material Cell Biology

Podocytes and autophagy: a potential therapeutic target in lupus nephritis

Xu-Jie Zhou et al.

AUTOPHAGY (2019)

Article Biochemistry & Molecular Biology

Gypenoside L Inhibits Proliferation of Liver and Esophageal Cancer Cells by Inducing Senescence

Jingxin Ma et al.

MOLECULES (2019)

Article Medicine, Research & Experimental

FoxO3 activation in hypoxic tubules prevents chronic kidney disease

Ling Li et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Review Biochemistry & Molecular Biology

Autophagy: Supporting cellular and organismal homeostasis by self-eating

Eeva-Liisa Eskelinen

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Molecular Interactions Between Reactive Oxygen Species and Autophagy in Kidney Disease

Gur P. Kaushal et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

Ginsenoside Compound K Induces Ros-Mediated Apoptosis and Autophagic Inhibition in Human Neuroblastoma Cells In Vitro and In Vivo

Jung-Mi Oh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Chemistry, Medicinal

Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation

Yong-Liang Yuan et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2019)

Review Oncology

Autophagy and its potent modulators from phytochemicals in cancer treatment

Chao-Yue Sun et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2019)

Review Biochemistry & Molecular Biology

Autophagy-dependent cell death

Donna Denton et al.

CELL DEATH AND DIFFERENTIATION (2019)

Article Cardiac & Cardiovascular Systems

Panax Notoginseng Saponins Attenuate Myocardial Ischemia-Reperfusion Injury Through the HIF-1α/BNIP3 Pathway of Autophagy

Xin-Wen Liu et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2019)

Article Biochemistry & Molecular Biology

An Autophagy Inducing Triterpene Saponin Derived from Aster koraiensis

Jaeyoung Kwon et al.

MOLECULES (2019)

Review Cell Biology

Autophagy in Chronic Kidney Diseases

Tien-An Lin et al.

Article Medicine, Research & Experimental

Eclalbasaponin I from Aralia elata (Miq.) Seem. reduces oxidative stress-induced neural cell death by autophagy activation

Wei Wang et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Plant Sciences

Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow

Ying Tang et al.

JOURNAL OF ETHNOPHARMACOLOGY (2018)

Article Pharmacology & Pharmacy

Akebia saponin D alleviates hepatic steatosis through BNip3 induced mitophagy

Li-li Gong et al.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis

Bernadette Carroll et al.

NATURE COMMUNICATIONS (2018)

Review Cell Biology

Autophagy-dependent cell death - where, how and why a cell eats itself to death

Shani Bialik et al.

JOURNAL OF CELL SCIENCE (2018)

Article Cell Biology

Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells

Yuheon Chung et al.

ANIMAL CELLS AND SYSTEMS (2018)

Article Biochemistry & Molecular Biology

Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice

Zhi-Meng Xu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Timosaponin AIII: A novel potential anti-tumor compound from Anemarrhena asphodeloides

Feng-Ying Han et al.

STEROIDS (2018)

Review Integrative & Complementary Medicine

Structural characteristics, bioavailability and cardioprotective potential of saponins

Deepika Singh et al.

INTEGRATIVE MEDICINE RESEARCH (2018)

Review Biochemistry & Molecular Biology

Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential

Danyi Yang et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Article Chemistry, Medicinal

Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells

Ye Wang et al.

ARCHIVES OF PHARMACAL RESEARCH (2017)

Article Cell Biology

Autophagy-from molecular mechanisms to clinical relevance

Monika Lippai et al.

CELL BIOLOGY AND TOXICOLOGY (2017)

Review Biochemistry & Molecular Biology

Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

Cynthia I. Chude et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Urology & Nephrology

Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

Andrey V. Cybulsky

NATURE REVIEWS NEPHROLOGY (2017)

Review Medicine, General & Internal

Autophagy and its link to type II diabetes mellitus

Jai-Sing Yang et al.

BIOMEDICINE-TAIWAN (2017)

Article Biochemistry & Molecular Biology

Elatoside C protects, against ox-LDL-induced HUVECs injury by Fox01-mediated autophagy induction

Yun Luo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)

Review Cell Biology

Autophagy and Tumor Metabolism

Alec C. Kimmelman et al.

CELL METABOLISM (2017)

Article Biochemistry & Molecular Biology

Paris saponin-induced autophagy promotes breast cancer cell apoptosis via the Akt/mTOR signaling pathway

Zhan-Zhi Xie et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2017)

Review Cell Biology

Autophagy and kidney inflammation

Tomonori Kimura et al.

AUTOPHAGY (2017)

Article Pharmacology & Pharmacy

Protective effect of Trillium tschonoskii saponin on CCl4-induced acute liver injury of rats through apoptosis inhibition

Hao Wu et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2016)

Article Biochemistry & Molecular Biology

Paris Saponin II induced apoptosis via activation of autophagy in human lung cancer cells

Lili Zhang et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2016)

Article Oncology

Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells

Meijuan Chen et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Therapeutic targeting of autophagy in cardiovascular disease

Gabriele G. Schiattarella et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)

Review Biochemistry & Molecular Biology

Regulation of Autophagy By Signaling Through the Atg1/ULK1 Complex

Daniel Papinski et al.

JOURNAL OF MOLECULAR BIOLOGY (2016)

Review Urology & Nephrology

Autophagy in acute kidney injury

Gur P. Kaushal et al.

KIDNEY INTERNATIONAL (2016)

Review Biochemistry & Molecular Biology

Saponins from Chinese Medicines as Anticancer Agents

Xiao-Huang Xu et al.

MOLECULES (2016)

Review Biochemistry & Molecular Biology

Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury

Pu Duann et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Pharmacology & Pharmacy

Akebia Saponin D Decreases Hepatic Steatosis through Autophagy Modulation

Li-li Gong et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)

Review Biochemistry & Molecular Biology

MAPK/JNK signalling: a potential autophagy regulation pathway

Yuan-Yuan Zhou et al.

BIOSCIENCE REPORTS (2015)

Editorial Material Biochemistry & Molecular Biology

Quick guide Lysosomes

Lena Wartosch et al.

CURRENT BIOLOGY (2015)

Article Biochemistry & Molecular Biology

p62 links autophagy and Nrf2 signaling

Tao Jiang et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Article Toxicology

Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models

Xinwen Liu et al.

TOXICOLOGY MECHANISMS AND METHODS (2015)

Article Toxicology

Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models

Xinwen Liu et al.

TOXICOLOGY MECHANISMS AND METHODS (2015)

Review Chemistry, Medicinal

Neuroprotection by Saponins

Aijing Sun et al.

PHYTOTHERAPY RESEARCH (2015)

Review Pharmacology & Pharmacy

Targeting autophagy in neurodegenerative diseases

Rene L. Vidal et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2014)

Review Biochemistry & Molecular Biology

Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy

Hitoshi Nakatogawa

AUTOPHAGY: MOLECULES AND MECHANISMS (2013)

Article Food Science & Technology

Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells

Mei-Ying Xu et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

Article Biochemistry & Molecular Biology

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

Yoshinobu Ichimura et al.

MOLECULAR CELL (2013)

Article Cell Biology

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

Ryan C. Russell et al.

NATURE CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Three new neuritogenic steroidal saponins from Ophiopogon japonicus (Thunb.) Ker-Gawl

Ying Ye et al.

STEROIDS (2013)

Article Cell Biology

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

Xianghai Liao et al.

CELL METABOLISM (2012)

Article Multidisciplinary Sciences

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

Richard C. Wang et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

The serine/threonine kinase ULK1 is a target of multiple phosphorylation events

Markus Bach et al.

BIOCHEMICAL JOURNAL (2011)

Article Biochemistry & Molecular Biology

Activation of Autophagy of Aggregation-prone Ubiquitinated Proteins by Timosaponin A-III

Chun-Nam Lok et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre et al.

SCIENCE (2011)

Article Pharmacology & Pharmacy

Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells

Young-Ok Son et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)

Article Cell Biology

Autophagy regulation by p53

Maria Chiara Maiuri et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Review Gastroenterology & Hepatology

Autophagy in liver diseases

Pierre-Emmanuel Rautou et al.

JOURNAL OF HEPATOLOGY (2010)

Article Biochemistry & Molecular Biology

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

Alexandria Lau et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

Jianrong Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

Gregory Bellot et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Cell Biology

LAMP-2 - A control step for phagosome and autophagosome maturation

Paul Saftig et al.

AUTOPHAGY (2008)

Article Peripheral Vascular Disease

Autophagy in Atherosclerosis

Wim Martinet et al.

CURRENT ATHEROSCLEROSIS REPORTS (2008)

Article Biochemistry & Molecular Biology

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

Huafeng Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy

Yongjie Wei et al.

MOLECULAR CELL (2008)

Article Cell Biology

FoxO3 controls autophagy in skeletal muscle in vivo

Cristina Mammucari et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

Serhiy Pankiv et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Biochemistry & Molecular Biology

AKT/PKB signaling: Navigating downstream

Brendan D. Manning et al.

Article Pharmacology & Pharmacy

Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Aβ(25-35)-treated cortical neurons

Rie Naito et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)

Review Oncology

The role of autophagy in cancer development and response to therapy

Y Kondo et al.

NATURE REVIEWS CANCER (2005)

Review Biochemistry & Molecular Biology

Nrf2-Keap1 defines a physiologically important stress response mechanism

H Motohashi et al.

TRENDS IN MOLECULAR MEDICINE (2004)

Review Cell Biology

The vacuolar (H+)-atpases -: Nature's most versatile proton pumps

T Nishi et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Review Cell Biology

MAPK-regulated transcription: A continuously variable gene switch?

CA Hazzalin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)