相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation
Kai Wang et al.
CARCINOGENESIS (2020)
Misaponin B Induces G2/M Arrest, Cytokinesis Failure and Impairs Autophagy
Gunho Won et al.
BIOMED RESEARCH INTERNATIONAL (2020)
Escins Isolated from Aesculus chinensis Bge. Promote the Autophagic Degradation of Mutant Huntingtin and Inhibit its Induced Apoptosis in HT22 cells
Yueshan Sun et al.
FRONTIERS IN PHARMACOLOGY (2020)
A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma
Jingwen Xu et al.
STEROIDS (2020)
Cytotoxicity of a naturally occuring spirostanol saponin, progenin III, towards a broad range of cancer cell lines by induction of apoptosis, autophagy and necroptosis
Armelle T. Mbaveng et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2020)
Liriopesides B induces apoptosis and cell cycle arrest in human non-small cell lung cancer cells
Hongxu Sheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)
The role of Neu1 in the protective effect of dipsacoside B on acetaminophen-induced liver injury
Shuang Chen et al.
ANNALS OF TRANSLATIONAL MEDICINE (2020)
A Bioactive compound Shatavarin IV-mediated longevity as revealed by dietary restriction-induced autophagy inCaenorhabditis elegans
Shachi Shuchi Smita et al.
BIOGERONTOLOGY (2020)
Hormesis and Ginseng: Ginseng Mixtures and Individual Constituents Commonly Display Hormesis Dose Responses, Especially for Neuroprotective Effects
Edward J. Calabrese
MOLECULES (2020)
SSPH I, a Novel Anti-Cancer Saponin, Inhibits Autophagy and Induces Apoptosis via ROS Accumulation and ERK1/2 Signaling Pathway in Hepatocellular Carcinoma Cells
Jin-ling Zhou et al.
ONCOTARGETS AND THERAPY (2020)
Paris saponin II-induced paraptosis-associated cell death increased the sensitivity of cisplatin
Shuli Man et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy
Chengni Jin et al.
FOOD & FUNCTION (2020)
A formulated red ginseng extract inhibits autophagic flux and sensitizes to doxorubicin-induced cell death
Han-Hee Park et al.
JOURNAL OF GINSENG RESEARCH (2019)
TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells
Bin Li et al.
ACTA PHARMACOLOGICA SINICA (2019)
Autophagy in Human Health and Disease: Novel Therapeutic Opportunities
Francesca Giampieri et al.
ANTIOXIDANTS & REDOX SIGNALING (2019)
PP-22 promotes autophagy and apoptosis in the nasopharyngeal carcinoma cell line CNE-2 by inducing endoplasmic reticulum stress, downregulating STAT3 signaling, and modulating the MAPK pathway
Gui-Xiang Tan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Podocytes and autophagy: a potential therapeutic target in lupus nephritis
Xu-Jie Zhou et al.
AUTOPHAGY (2019)
Targeting autophagy using natural compounds for cancer prevention and therapy
Shuo Deng et al.
CANCER (2019)
Gypenoside L Inhibits Proliferation of Liver and Esophageal Cancer Cells by Inducing Senescence
Jingxin Ma et al.
MOLECULES (2019)
Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy
Ping Zhou et al.
CELLS (2019)
FoxO3 activation in hypoxic tubules prevents chronic kidney disease
Ling Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Eclalbasaponin I causes mitophagy to repress oxidative stress-induced apoptosis via activation of p38 and ERK in SH-SY5Y cells
Wei Wang et al.
FREE RADICAL RESEARCH (2019)
Autophagy: Supporting cellular and organismal homeostasis by self-eating
Eeva-Liisa Eskelinen
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)
Molecular Interactions Between Reactive Oxygen Species and Autophagy in Kidney Disease
Gur P. Kaushal et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Ginsenoside Compound K Induces Ros-Mediated Apoptosis and Autophagic Inhibition in Human Neuroblastoma Cells In Vitro and In Vivo
Jung-Mi Oh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation
Yong-Liang Yuan et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2019)
Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy
Jingjing Liu et al.
JOURNAL OF DIABETES RESEARCH (2019)
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer
Yannan Liu et al.
BIOCHEMICAL PHARMACOLOGY (2019)
Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway
Shi-long Jiang et al.
ACTA PHARMACOLOGICA SINICA (2019)
Ginsenoside metabolite compound K induces apoptosis and autophagy in non-small cell lung cancer cells via AMPK-mTOR and JNK pathways
Chen Li et al.
BIOCHEMISTRY AND CELL BIOLOGY (2019)
Autophagy and its potent modulators from phytochemicals in cancer treatment
Chao-Yue Sun et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2019)
Autophagy-dependent cell death
Donna Denton et al.
CELL DEATH AND DIFFERENTIATION (2019)
The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis
Jingxia Cui et al.
CELL PROLIFERATION (2019)
Panax Notoginseng Saponins Attenuate Myocardial Ischemia-Reperfusion Injury Through the HIF-1α/BNIP3 Pathway of Autophagy
Xin-Wen Liu et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2019)
An Autophagy Inducing Triterpene Saponin Derived from Aster koraiensis
Jaeyoung Kwon et al.
MOLECULES (2019)
Anticancer effect of Polyphyllin in colorectal cancer cells through ROS-dependent autophagy and G2/M arrest mechanisms
Si Yu et al.
NATURAL PRODUCT RESEARCH (2018)
Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy
Bin Li et al.
ACTA PHARMACOLOGICA SINICA (2018)
Hydrolysis product of Nigella A obtained from Nigella glandulifera Freyn seeds promotes apoptosis and AMPK-mediated autophagy in human colon cancer SW620 cells
Lili Chen et al.
ARCHIVES OF BIOLOGICAL SCIENCES (2018)
Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells
Qian Wu et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Eclalbasaponin I from Aralia elata (Miq.) Seem. reduces oxidative stress-induced neural cell death by autophagy activation
Wei Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Trillium tschonoskii maxim saponin mitigates D-galactose-induced brain aging of rats through rescuing dysfunctional autophagy mediated by Rhebm-TOR signal pathway
Lingjie Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Celosins inhibit atherosclerosis in ApoE-/- mice and promote autophagy flow
Ying Tang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2018)
Akebia saponin D alleviates hepatic steatosis through BNip3 induced mitophagy
Li-li Gong et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2018)
Apoptosis and pro-death autophagy induced by a spirostanol saponin isolated from Rohdea chinensis (Baker) N. Tanaka (synonym Tupistra chinensis Baker) on HL-60 cells
Xiaomin Yi et al.
PHYTOMEDICINE (2018)
Paris saponin VII induces cell cycle arrest and apoptosis by regulating Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells
Ting Yan et al.
PHYTOTHERAPY RESEARCH (2018)
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis
Bernadette Carroll et al.
NATURE COMMUNICATIONS (2018)
Autophagy-dependent cell death - where, how and why a cell eats itself to death
Shani Bialik et al.
JOURNAL OF CELL SCIENCE (2018)
Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells
Yuheon Chung et al.
ANIMAL CELLS AND SYSTEMS (2018)
Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice
Zhi-Meng Xu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy
Ping Zhou et al.
MOLECULES (2018)
Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells
Richa Sachan et al.
PHYTOMEDICINE (2018)
Timosaponin AIII: A novel potential anti-tumor compound from Anemarrhena asphodeloides
Feng-Ying Han et al.
STEROIDS (2018)
Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of raddeanin A against human breast cancer cells in vitro
Yi-di Guan et al.
ACTA PHARMACOLOGICA SINICA (2018)
Structural characteristics, bioavailability and cardioprotective potential of saponins
Deepika Singh et al.
INTEGRATIVE MEDICINE RESEARCH (2018)
Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential
Danyi Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells
Ye Wang et al.
ARCHIVES OF PHARMACAL RESEARCH (2017)
Autophagy-from molecular mechanisms to clinical relevance
Monika Lippai et al.
CELL BIOLOGY AND TOXICOLOGY (2017)
Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors
Cynthia I. Chude et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Dioscin enhances osteoblastic cell differentiation and proliferation by inhibiting cell autophagy via the ASPP2/NF-κβ pathway
Chen Zhu et al.
MOLECULAR MEDICINE REPORTS (2017)
Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases
Andrey V. Cybulsky
NATURE REVIEWS NEPHROLOGY (2017)
Modified Panax ginseng extract regulates autophagy by AMPK signaling in A549 human lung cancer cells
Hwa-Seung Yoo et al.
ONCOLOGY REPORTS (2017)
Panax notoginseng saponins mitigate cisplatin induced nephrotoxicity by inducing mitophagy via HIF-1α
Xueyan Liang et al.
ONCOTARGET (2017)
A triterpenoidal saponin fraction of Conyza blinii H.Lev. is a dual-targeting autophagy inhibitor for HeLa cells
Haiyan Liu et al.
RSC ADVANCES (2017)
Autophagy and its link to type II diabetes mellitus
Jai-Sing Yang et al.
BIOMEDICINE-TAIWAN (2017)
Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
Rachel K. Toth et al.
ANTIOXIDANTS (2017)
Elatoside C protects, against ox-LDL-induced HUVECs injury by Fox01-mediated autophagy induction
Yun Luo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Regulation of different components from Ophiopogon japonicus on autophagy in human lung adenocarcinoma A549Cells through PI3K/Akt/mTOR signaling pathway
Juan Chen et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Paris saponin-induced autophagy promotes breast cancer cell apoptosis via the Akt/mTOR signaling pathway
Zhan-Zhi Xie et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2017)
Long-term Course of Alzheimer Disease in Patients Treated According to the Dutch Dementia Guideline at a Memory Clinic A Real-Life Study
Erika Droogsma et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2016)
Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint
Kai Zheng et al.
AUTOPHAGY (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Protective effect of Trillium tschonoskii saponin on CCl4-induced acute liver injury of rats through apoptosis inhibition
Hao Wu et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2016)
Paris Saponin II induced apoptosis via activation of autophagy in human lung cancer cells
Lili Zhang et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation
Hongyang Li et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways
Yashi Mi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells
Meijuan Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Gypenoside XVII Enhances Lysosome Biogenesis and Autophagy Flux and Accelerates Autophagic Clearance of Amyloid-beta through TFEB Activation
Xiangbao Meng et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Therapeutic targeting of autophagy in cardiovascular disease
Gabriele G. Schiattarella et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Regulation of Autophagy By Signaling Through the Atg1/ULK1 Complex
Daniel Papinski et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells
Won Kyung Kim et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Autophagy in acute kidney injury
Gur P. Kaushal et al.
KIDNEY INTERNATIONAL (2016)
Effects of ophiopogonin B on the proliferation and apoptosis of SGC-7901 human gastric cancer cells
Weiyue Zhang et al.
MOLECULAR MEDICINE REPORTS (2016)
Saponins from Chinese Medicines as Anticancer Agents
Xiao-Huang Xu et al.
MOLECULES (2016)
Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells
Yu Shan et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2016)
Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells
Shanshan Jiang et al.
PHYTOMEDICINE (2016)
Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells
Ming-Ju Hsieh et al.
PHYTOMEDICINE (2016)
Raddeanoside R13 inhibits breast cancer cell proliferation, invasion, and metastasis
Yingchun Liang et al.
TUMOR BIOLOGY (2016)
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release
Chenghui Liao et al.
ONCOTARGET (2016)
Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo
Jui-Chieh Chen et al.
ONCOTARGET (2016)
LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
Virginie Hubert et al.
BIOLOGY OPEN (2016)
Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells
Chao Zhang et al.
PLOS ONE (2016)
Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury
Pu Duann et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Akebia Saponin D Decreases Hepatic Steatosis through Autophagy Modulation
Li-li Gong et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells
Ting Li et al.
ACTA PHARMACOLOGICA SINICA (2015)
Pulsatilla Saponin D Inhibits Autophagic Flux and Synergistically Enhances the Anticancer Activity of Chemotherapeutic Agents Against HeLa Cells
Yulin Zhang et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2015)
Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
Caroline Mauvezin et al.
AUTOPHAGY (2015)
MAPK/JNK signalling: a potential autophagy regulation pathway
Yuan-Yuan Zhou et al.
BIOSCIENCE REPORTS (2015)
Quick guide Lysosomes
Lena Wartosch et al.
CURRENT BIOLOGY (2015)
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells
Ting Li et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
p62 links autophagy and Nrf2 signaling
Tao Jiang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Inhibition of autophagy ameliorates atherogenic inflammation by augmenting apigenin-induced macrophage apoptosis
Qun Wang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2015)
Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells
Ya-Min Shi et al.
PHYTOMEDICINE (2015)
Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models
Xinwen Liu et al.
TOXICOLOGY MECHANISMS AND METHODS (2015)
Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models
Xinwen Liu et al.
TOXICOLOGY MECHANISMS AND METHODS (2015)
Platycodin-D Induced Autophagy in Non-Small Cell Lung Cancer Cells via PI3K/Akt/mTOR and MAPK Signaling Pathways
Ruolin Zhao et al.
JOURNAL OF CANCER (2015)
Neuroprotection by Saponins
Aijing Sun et al.
PHYTOTHERAPY RESEARCH (2015)
Deltonin induced both apoptosis and autophagy in head and neck squamous carcinoma FaDu cell
Y. L. Xie et al.
NEOPLASMA (2015)
Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae
Roy Emanuel et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
David Heras-Sandoval et al.
CELLULAR SIGNALLING (2014)
Antitumor Activity of Jujuboside B and the Underlying Mechanism via Induction of Apoptosis and Autophagy
Mei-Ying Xu et al.
JOURNAL OF NATURAL PRODUCTS (2014)
Stimulation of autophagic activity in human glioma cells by anti-proliferative ardipusilloside I isolated from Ardisia pusilla
Rong Wang et al.
LIFE SCIENCES (2014)
Effects of the Total Saponins from Rosa laevigata Michx Fruit against Acetaminophen-Induced Liver Damage in Mice via Induction of Autophagy and Suppression of Inflammation and Apoptosis
Deshi Dong et al.
MOLECULES (2014)
Targeting autophagy in neurodegenerative diseases
Rene L. Vidal et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy
Jaemoo Chun et al.
TUMOR BIOLOGY (2014)
20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin
Dong-Gun Kim et al.
ONCOTARGET (2014)
Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress
Jun-Min Shi et al.
BIOCHEMICAL PHARMACOLOGY (2013)
Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
Soo Han Bae et al.
CELL METABOLISM (2013)
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
Jing Zhou et al.
CELL RESEARCH (2013)
Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy
Hitoshi Nakatogawa
AUTOPHAGY: MOLECULES AND MECHANISMS (2013)
Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells
Mei-Ying Xu et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells
An-Guo Wu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
Yoshinobu Ichimura et al.
MOLECULAR CELL (2013)
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Ryan C. Russell et al.
NATURE CELL BIOLOGY (2013)
Three new neuritogenic steroidal saponins from Ophiopogon japonicus (Thunb.) Ker-Gawl
Ying Ye et al.
STEROIDS (2013)
FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway
Jingyi Zhou et al.
AUTOPHAGY (2012)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
Xianghai Liao et al.
CELL METABOLISM (2012)
Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation
Richard C. Wang et al.
SCIENCE (2012)
The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy
Eun-Ju Lee et al.
AUTOPHAGY (2011)
The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
Markus Bach et al.
BIOCHEMICAL JOURNAL (2011)
Activation of Autophagy of Aggregation-prone Ubiquitinated Proteins by Timosaponin A-III
Chun-Nam Lok et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells
Young-Ok Son et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Autophagy regulation by p53
Maria Chiara Maiuri et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Autophagy in liver diseases
Pierre-Emmanuel Rautou et al.
JOURNAL OF HEPATOLOGY (2010)
A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
Alexandria Lau et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
Kenji Satoo et al.
EMBO JOURNAL (2009)
A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1
Jianrong Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
Gregory Bellot et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
LAMP-2 - A control step for phagosome and autophagosome maturation
Paul Saftig et al.
AUTOPHAGY (2008)
Timosaponin A-III Induces Autophagy Preceding Mitochondria-Mediated Apoptosis in HeLa Cancer Cells
Lai-King Sy et al.
CANCER RESEARCH (2008)
Autophagy in Atherosclerosis
Wim Martinet et al.
CURRENT ATHEROSCLEROSIS REPORTS (2008)
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
Huafeng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
FoxO3 controls autophagy in skeletal muscle in vivo
Cristina Mammucari et al.
CELL METABOLISM (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
AKT/PKB signaling: Navigating downstream
Brendan D. Manning et al.
CELL (2007)
The regulation of AMPK β1, TSC2, and PTEN expression by p53:: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
Zhaohui Feng et al.
CANCER RESEARCH (2007)
Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Aβ(25-35)-treated cortical neurons
Rie Naito et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)
Phosphorylation and functional inactivation of TSC2 by Erk: Implications for tuberous sclerosis and cancer pathogenesis
Li Ma et al.
CELL (2006)
Phosphorylation and functional inactivation of TSC2 by Erk: Implications for tuberous sclerosis and cancer pathogenesis
L Ma et al.
CELL (2005)
The role of autophagy in cancer development and response to therapy
Y Kondo et al.
NATURE REVIEWS CANCER (2005)
Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins
AA Ellington et al.
CARCINOGENESIS (2005)
Nrf2-Keap1 defines a physiologically important stress response mechanism
H Motohashi et al.
TRENDS IN MOLECULAR MEDICINE (2004)
The vacuolar (H+)-atpases -: Nature's most versatile proton pumps
T Nishi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
MAPK-regulated transcription: A continuously variable gene switch?
CA Hazzalin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)