4.8 Article

Electrochemiluminescent Chiral Discrimination with a Pillar[5]arene Molecular Universal Joint-Coordinated Ruthenium Complex

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ORGANIC LETTERS
卷 23, 期 10, 页码 3885-3890

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c01016

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资金

  1. National Natural Science Foundation of China [92056116, 21871194, 21971169, 21572142]
  2. National Key Research and Development Program of China [2017YFA0505903]
  3. Science & Technology Department of Sichuan Province [2019YJ0160, 2019YJ0090, 2017SZ0021]
  4. Fundamental Research Funds for the Central Universities [20826041D4117]
  5. Comprehensive Training Platform of Specialized Laboratory, College of Chemistry, Analytical & Testing Center, Sichuan University

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A bicyclic pillar[5]arene derivative fused with a bipyridine side ring, named a molecular universal joint (MUJ), was synthesized and the pair of enantiomers was resolved using high-performance liquid chromatography. The electrochemiluminescent detection based on the ruthenium complex of enantiopure MUJ demonstrated excellent chiral discrimination towards certain amino acids.
A bicyclic pillar[5]arene derivative fused with a bipyridine side ring, a so-called molecular universal joint (MUJ), was synthesized, and the pair of enantiomers was resolved by high-performance liquid chromatography enantioresolution. The electrochemiluminescent detection based on the ruthenium complex of the enantiopure MUJ showed excellent chiral discrimination toward certain amino acids.

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