4.8 Article

Five-Step Total Synthesis of (±)-Aspidospermidine by a Lactam Strategy via an Azomethine Ylide

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Enantioselective Reductive Cyanation and Phosphonylation of Secondary Amides by Iridium and Chiral Thiourea Sequential Catalysis

Dong-Huang Chen et al.

Summary: The combination of transition-metal catalysis and organocatalysis has enabled chemists to achieve direct enantioselective reductive cyanation and phosphonylation of secondary amides, synthesizing enantioenriched chiral alpha-aminonitriles and alpha-aminophosphonates for the first time. The protocol is efficient, enantioselective, scalable, and the thiourea catalyst can be recycled and reused.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Transition-Metal-Free Reductive Functionalization of Tertiary Carboxamides and Lactams for α-Branched Amine Synthesis

Derek Yiren Ong et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Reductive Functionalization of Carboxamides: A Recent Update

Derek Yiren Ong et al.

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2020)

Article Chemistry, Organic

Total Synthesis of (+)-Aspidospermidine

Hongjin Xu et al.

ORGANIC LETTERS (2019)

Review Chemistry, Multidisciplinary

Direct Transformations of Amides: Tactics and Recent Progress

Huang Pei-Qiang

ACTA CHIMICA SINICA (2018)

Article Chemistry, Multidisciplinary

Iridium-Catalyzed Reductive Alkylations of Secondary Amides

Wei Ou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Organic

Hydrozirconation of C=X Functionalities with Schwartz's Reagent

Michal M. Wieclaw et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Chemistry, Physical

Concise total synthesis of (+/-)-aspidospermidine and computational study: FT-IR, NMR, NBO, NLO, FMO, MEP diagrams

Goncagul Serdaroglu et al.

JOURNAL OF MOLECULAR STRUCTURE (2018)

Review Chemistry, Organic

Total synthesis of complex alkaloids by nucleophilic addition to amides

Takaaki Sato et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Article Multidisciplinary Sciences

Iridium-catalyzed reductive Ugi-type reactions of tertiary amides

Lan-Gui Xie et al.

NATURE COMMUNICATIONS (2018)

Article Chemistry, Multidisciplinary

Straightforward α-Amino Nitrile Synthesis Through Mo(CO)6-Catalyzed Reductive Functionalization of Carboxamides

Paz Trillo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Multidisciplinary

Amide activation: an emerging tool for chemoselective synthesis

Daniel Kaiser et al.

CHEMICAL SOCIETY REVIEWS (2018)

Article Chemistry, Organic

Iridium-Catalyzed Reductive Nucleophilic Addition to Secondary Amides

Yoshito Takahashi et al.

ORGANIC LETTERS (2018)

Article Chemistry, Organic

Use of nitrogen and oxygen dipole ylides for alkaloid synthesis

Albert Padwa

ARKIVOC (2018)

Article Chemistry, Multidisciplinary

Total Synthesis of (-)-Histrionicotoxin through a Stereoselective Radical Translocation-Cyclization Reaction

Manabu Sato et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Unified Total Synthesis of Stemoamide-Type Alkaloids by Chemoselective Assembly of Five-Membered Building Blocks

Makoto Yoritate et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Chemistry, Multidisciplinary

Reductive Approach to Nitrones from N-Siloxyamides and N-Hydroxyamides

Seiya Katahara et al.

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2017)

Article Chemistry, Multidisciplinary

Iridium-Catalyzed Reductive Strecker Reaction for Late-Stage Amide and Lactam Cyanation

Angel L. Fuentes de Arriba et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(I) bis-metal sequential catalysis

Pei-Qiang Huang et al.

CHEMICAL COMMUNICATIONS (2016)

Review Chemistry, Multidisciplinary

Chemoselective reduction of carboxamides

Atexey Volkov et al.

CHEMICAL SOCIETY REVIEWS (2016)

Article Chemistry, Organic

One-Pot Reductive 1,3-Dipolar Cycloaddition of Secondary Amides: A Two-Step Transformation of Primary Amides

Pei-Qiang Huang et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

Article Chemistry, Multidisciplinary

An Iridium-Catalyzed Reductive Approach to Nitrones from N-Hydroxyamides

Seiya Katahara et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Chemistry, Organic

Concise total synthesis of (±)-aspidospermidine

Haichen Ma et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2015)

Article Chemistry, Organic

Iridium-Catalyzed Chemoselective Reductive Nucleophilic Addition to N-Methoxyamides

Minami Nakajima et al.

ORGANIC LETTERS (2015)

Article Chemistry, Multidisciplinary

Iridium-Catalyzed Reductive Nitro-Mannich Cyclization

Alex W. Gregory et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

Review Chemistry, Applied

Increasing the Reactivity of Amides towards Organometallic Reagents: An Overview

Vittorio Pace et al.

ADVANCED SYNTHESIS & CATALYSIS (2014)

Article Chemistry, Multidisciplinary

Total Synthesis of (±)-Gephyrotoxin by Amide-Selective Reductive Nucleophilic Addition

Kenji Shirokane et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Concise and Enantioselective Total Synthesis of (-)-Mehranine, (-)-Methylenebismehranine, and Related Aspidosperma Alkaloids

Marius Mewald et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Organic

Nucleophilic addition to N-alkoxyamides

Takaaki Sato et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2014)

Article Chemistry, Multidisciplinary

Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation

Kai-Jiong Xiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Article Chemistry, Multidisciplinary

Chemical Synthesis of Aspidosperma Alkaloids Inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products

Lindsay McMurray et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Review Chemistry, Multidisciplinary

Thioamides and Thioformamides for Sequential Reactions with Organolithium and Grignard Reagents

Toshiaki Murai et al.

CHEMISTRY LETTERS (2012)

Article Chemistry, Multidisciplinary

Total Synthesis of Manzamine A and Related Alkaloids

Pavol Jakubec et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Chemistry, Multidisciplinary

Pd(II)-Catalyzed Regioselective 2-Alkylation of Indoles via a Norbornene-Mediated C-H Activation: Mechanism and Applications

Lei Jiao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Review Chemistry, Multidisciplinary

Generation of Secondary, Tertiary, and Quaternary Centers by Geminal Disubstitution of Carbonyl Oxygens

Dieter Seebach

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Chemistry, Multidisciplinary

Stereodivergent Synthesis of Substituted N,O-Containing Bicyclic Compounds by Sequential Addition of Nucleophiles to N-Alkoxybicyclolactams

Guillaume Vincent et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Multidisciplinary Sciences

Collective synthesis of natural products by means of organocascade catalysis

Spencer B. Jones et al.

NATURE (2011)

Article Chemistry, Multidisciplinary

A Direct Entry to Substituted N-Methoxyamines from N-Methoxyamides via N-Oxyiminium Ions

Kenji Shirokane et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation

Kai-Jiong Xiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine

Filippo De Simone et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Total Synthesis of (±)-Aspidospermidine Starting from 3-Ethyl-5-bromo-2-pyrone

Hyun-Kyu Cho et al.

BULLETIN OF THE KOREAN CHEMICAL SOCIETY (2010)

Article Chemistry, Organic

'Aromatic ring umpolung', a rapid access to the main core of several natural products

Kimiaka C. Guerard et al.

TETRAHEDRON (2010)

Article Chemistry, Multidisciplinary

Concise total synthesis of (+/-)-aspidospermidine via an oxidative Hosomi-Sakurai process

Cyrille Sabot et al.

CHEMICAL COMMUNICATIONS (2009)

Review Chemistry, Organic

Amidyls in radical cascades.: The total synthesis of (±)-aspidospermidine and (±)-13-deoxyserratine

Anne-Claude Callier-Dublanchet et al.

TETRAHEDRON (2008)

Article Chemistry, Organic

A short total synthesis of (±)-aspidospermidine

LA Sharp et al.

ORGANIC LETTERS (2006)

Review Biochemistry & Molecular Biology

Chemistry and biology of monoterpene indole alkaloid biosynthesis

Sarah E. O'Connor et al.

NATURAL PRODUCT REPORTS (2006)

Review Chemistry, Multidisciplinary

Intramolecular dipolar cycloaddition reactions of azomethine ylides

I Coldham et al.

CHEMICAL REVIEWS (2005)

Article Chemistry, Multidisciplinary

Total synthesis of (+)-aspidospermidine: A new strategy for the enantiospecific synthesis of aspidosperma alkaloids

JP Marino et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Article Chemistry, Organic

Concise synthesis of (±)-rhazinilam

P Magnus et al.

TETRAHEDRON (2001)

Article Chemistry, Organic

Total synthesis of (±)-aspidospermidine

MA Toczko et al.

JOURNAL OF ORGANIC CHEMISTRY (2000)