4.7 Article

Development and analysis of surface plasmon resonance based refractive index sensor for pregnancy testing

期刊

OPTICS AND LASERS IN ENGINEERING
卷 140, 期 -, 页码 -

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ELSEVIER SCI LTD
DOI: 10.1016/j.optlaseng.2021.106551

关键词

Photonic crystal fiber; Pregnancy test; Surface plasmon resonance; Human chorionic gonadotropin; Detection; Refractive index sensor

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资金

  1. National Science, Technology and Innovation Plan (MAARIFAH), the King Abdul-Aziz City for Science and Technology (KACST), Kingdom of Saudi Arabia [12-INF2970-10]

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The proposed two-dimensional photonic crystal fiber sensor based on SPR has shown significant sensitivity in urine observation. By analyzing normal and pregnant urine with various optical parameters, the sensor demonstrated high sensitivity response and resolution, with numerical investigations using FEM. This research aims to develop optoelectronics and laser biosensor concepts for biological detection systems, offering potential applications in modified optical fibers for biological changes.
In the proposed work, a two-dimensional photonic crystal fiber (PCF) based on the surface plasmon resonance (SPR) refractive index sensor has been demonstrated and designed which is so much helpful to gain a better sensitivity response in urine observation. In order to detect the pregnancy, the simulation and analysis have been performed in both normal and pregnant urine with the effective refractive indices values of 1.335, 1.34, 1.342 and 1.343 within the range of working wavelength from 1.75 mu m to 2 mu m. From this testing sensor, the optical parameters of the dispersion relation, birefringence, coupling length, confinement loss, insertion loss, sensor length, crosstalk, sensitivity response, resonance wavelength, resolution, and sensitivity per line-width have been analyzed. Besides, Finite element method (FEM) is used for the numerical investigations. From this investigation, the highest value of sensitivity response, sensitivity per line-width, and the resolution of 68051.344 nm/RIU, 314 RIU-1, and 9.39 x 10(-6) RIU are gained. It is noted that the proposed sensor offers significant sensing performances for the polarized modes. The main goal of this investigation is to develop the concepts of optoelectronics and laser bio-sensor in the field of biological detection systems. As a result, this structure of optical biosensor will be applicable through the modified optical fiber in biological changes.

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