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Konstantin N. Bulygin et al.
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Mary E. Matyskiela et al.
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Alireza Baradaran-Heravi et al.
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Tissue-based map of the human proteome
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Leenus Martin et al.
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Xia Zhao et al.
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Eli Shulman et al.
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Residual α-L-iduronidase activity in fibroblasts of mild to severe Mucopolysaccharidosis type I patients
Esmee Oussoren et al.
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O'neil W. Guthrie
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Celine Chauvin et al.
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I Kashima et al.
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C Chauvin et al.
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H Luesch et al.
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J Salas-Marco et al.
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The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein
R Hegde et al.
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J Carnes et al.
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KM Keeling et al.
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CG Jakobsen et al.
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D Curman et al.
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