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Antibody Responses after a Single Dose of SARS-CoV-2 mRNA Vaccine

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NEW ENGLAND JOURNAL OF MEDICINE
卷 384, 期 20, 页码 1959-1961

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MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMc2102051

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A small study found that antibody responses significantly increased in healthcare workers after receiving a single dose of the SARS-CoV-2 vaccine, including antibodies to spike protein subunits S1 and S2, as well as the receptor-binding domain.
Antibody Responses after a Single Dose of SARS-CoV-2 Vaccine Reported results of immunization with SARS-CoV-2 vaccine have focused on two doses given to seronegative persons. In a small study involving health care workers, antibody responses were examined after a single dose of vaccine. Consistent increases in antibodies to spike protein subunits S1 and S2 and the receptor-binding domain were noted.

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