相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice
Xin Fang et al.
BRAIN RESEARCH (2020)
The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease
Alessandra Webers et al.
IMMUNOLOGY AND CELL BIOLOGY (2020)
Periphery inflammation promotes brain tau transmission via disrupting blood-brain barrier
Yanchao Liu et al.
BIOSCIENCE REPORTS (2020)
Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology
Janet E. Baulch et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2020)
Irisin and markers of metabolic derangement in non-diabetic Caucasian subjects with stage I-II obesity during early aging
Jonica Campolo et al.
PLOS ONE (2020)
Irisin: Still chasing shadows
Elke Albrecht et al.
MOLECULAR METABOLISM (2020)
Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture
Miriane de Oliveira et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner
Khaled S. Abd-Elrahman et al.
SCIENCE SIGNALING (2020)
FNDC5/Irisin inhibits pathological cardiac hypertrophy
Qing Yu et al.
CLINICAL SCIENCE (2019)
Impaired Glucose Tolerance and Reduced Plasma Insulin Precede Decreased AKT Phosphorylation and GLUT3 Translocation in the Hippocampus of Old 3xTg-AD Mice
Chelsea M. Griffith et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease
Elena P. Moreno-Jimenez et al.
NATURE MEDICINE (2019)
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice
Sami Gabbouj et al.
NEUROBIOLOGY OF AGING (2019)
Irisin and BDNF serum levels and behavioral disturbances in Alzheimer's disease
Elisa Conti et al.
NEUROLOGICAL SCIENCES (2019)
The effects of both age and sex on irisin levels in paired plasma and cerebrospinal fluid in healthy humans
Qingwei Ruan et al.
PEPTIDES (2019)
Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer's disease
Dawling A. Dionisio-Santos et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Irisin Attenuates Neuroinflammation and Prevents the Memory and Cognitive Deterioration in Streptozotocin-Induced Diabetic Mice
Kexin Wang et al.
MEDIATORS OF INFLAMMATION (2019)
Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders
Mohammad Fahad Ullah et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2019)
Irisin reverses insulin resistance in C2C12 cells via the p38-MAPK-PGC-1α pathway
Xiao Ye et al.
PEPTIDES (2019)
Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway
Sami Gabbouj et al.
FRONTIERS IN NEUROSCIENCE (2019)
Irisin Exerts Inhibitory Effect on Adipogenesis Through Regulation of Wnt Signaling
Eun Bi Ma et al.
FRONTIERS IN PHYSIOLOGY (2019)
Superiority of the Non-Glycosylated Form over the Glycosylated Form of Irisin in the Attenuation of Adipocytic Meta-Inflammation: A Potential Factor in the Fight against Insulin Resistance
Agnieszka Irena Mazur-Bialy
BIOMOLECULES (2019)
Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence
Hei-Man Chow et al.
NATURE NEUROSCIENCE (2019)
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models
Mychael V. Lourenco et al.
NATURE MEDICINE (2019)
Irisin Alleviates Advanced Glycation End Products-Induced Inflammation and Endothelial Dysfunction via Inhibiting ROS-NLRP3 Inflammasome Signaling
Xian Deng et al.
INFLAMMATION (2018)
Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice
Minesh Kapadia et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease
Christine M. Dengler-Crish et al.
NEUROBIOLOGY OF AGING (2018)
Irisin Peptide Protects Brain Against Ischemic Injury Through Reducing Apoptosis and Enhancing BDNF in a Rodent Model of Stroke
Yasin Asadi et al.
NEUROCHEMICAL RESEARCH (2018)
High irisin levels in overweight/obese children and its positive correlation with metabolic profile, blood pressure, and endothelial progenitor cells
F. De Meneck et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2018)
Detection and quantitation of irisin in human cerebrospinal fluid by tandem mass spectrometry
Qingwei Ruan et al.
PEPTIDES (2018)
Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway
Mohammad Azimi et al.
PEPTIDES (2018)
Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer's Disease
Alice E. Kane et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model
Se Hoon Choi et al.
SCIENCE (2018)
Sex Differences in Neuropathology and Cognitive Behavior in APP/PS1/tau Triple-Transgenic Mouse Model of Alzheimer's Disease
Jun-Ting Yang et al.
NEUROSCIENCE BULLETIN (2018)
Serum irisin is upregulated in patients affected by amyotrophic lateral sclerosis and correlates with functional and metabolic status
Christian Lunetta et al.
JOURNAL OF NEUROLOGY (2018)
The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation
Cuizhe Wang et al.
MEDIATORS OF INFLAMMATION (2018)
Molecular and Functional Interaction of the Myokine Irisin with Physical Exercise and Alzheimer's Disease
Yunho Jin et al.
MOLECULES (2018)
Variability in metabolic parameters and risk of dementia: a nationwide population-based study
Seung-Hwan Lee et al.
ALZHEIMERS RESEARCH & THERAPY (2018)
Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer's disease
Yasuha Noda et al.
MOLECULAR BRAIN (2018)
Irisin Ameliorates Glucolipotoxicity-Associated -Cell Dysfunction and Apoptosis via AMPK Signaling and Anti-Inflammatory Actions
Dan Zhang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
The Effect of Adherence to Screening Guidelines on the Risk of Alzheimer's Disease in Elderly Individuals Newly Diagnosed With Type 2 Diabetes Mellitus
Arseniy P. Yashkin et al.
GERONTOLOGY AND GERIATRIC MEDICINE (2018)
Inclusion of females does not increase variability in rodent research studies
Annaliese K. Beery
CURRENT OPINION IN BEHAVIORAL SCIENCES (2018)
Expression, purification and biological characterisation of recombinant human irisin (12.5 kDa)
Kalpana Panati et al.
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY (2018)
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease
Christine M. Dengler-Crish et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Glucose tolerance and insulin sensitivity are impaired in APP/PS1 transgenic mice prior to amyloid plaque pathogenesis and cognitive decline
Lauren Macklin et al.
EXPERIMENTAL GERONTOLOGY (2017)
Protein purification and analysis: next generation Western blotting techniques
Manish Mishra et al.
EXPERT REVIEW OF PROTEOMICS (2017)
Anti-Inflammatory Properties of Irisin, Mediator of Physical Activity, Are Connected with TLR4/MyD88 Signaling Pathway Activation
Agnieszka Irena Mazur-Bialy et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia
Dong-Jie Li et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2017)
DIFFERENTIAL RESPONSE TO INTRAHIPPOCAMPAL INTERLEUKIN-4/INTERLEUKIN-13 IN AGED AND EXERCISE MICE
Alyssa Littlefield et al.
NEUROSCIENCE (2017)
Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury
Ken Chen et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism
Jin Zhang et al.
BONE RESEARCH (2017)
N-Glycosylation is required for FDNC5 stabilization and irisin secretion
Yongwei Nie et al.
BIOCHEMICAL JOURNAL (2017)
Irisin-mediated protective effect on LPS-induced acute lung injury via suppressing inflammation and apoptosis of alveolar epithelial cells
Lei Shao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology
Katharina Stratmann et al.
BRAIN PATHOLOGY (2016)
Irisin ameliorates depressive-like behaviors in rats by regulating energy metabolism
Sisi Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Effects of exercise on Irisin, BDNF and IL-6 serum levels in patients with progressive multiple sclerosis
Sven Briken et al.
JOURNAL OF NEUROIMMUNOLOGY (2016)
IMPAIRED BURROWING IS THE MOST PROMINENT BEHAVIORAL DEFICIT OF AGING HTAU MICE
Philippine Camilla Geiszler et al.
NEUROSCIENCE (2016)
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
B. M. Varela-Rodriguez et al.
SCIENTIFIC REPORTS (2016)
The role of sex, adiposity, and gonadectomy in the regulation of irisin secretion
M. Zuegel et al.
ENDOCRINE (2016)
FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity
Xiao-Qing Xiong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Fndc5 overexpression facilitated neural differentiation of mouse embryonic stem cells
Mahboobeh Forouzanfar et al.
CELL BIOLOGY INTERNATIONAL (2015)
Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
Tong-Yan Liu et al.
CLINICAL SCIENCE (2015)
Irisin-encoding gene (FNDC5) variant is associated with changes in blood pressure and lipid profile in type 2 diabetic women but not in men
Leticia A. Brondani et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2015)
The myokine irisin increases cortical bone mass
Graziana Colaianni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A comprehensive immunohistochemical examination of the distribution of the fat-burning protein irisin in biological tissues
Suleyman Aydin et al.
PEPTIDES (2014)
GSK3β, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression
Jan Platenik et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2014)
Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
Christiane D. Wrann et al.
CELL METABOLISM (2013)
The Structure of Irisin Reveals a Novel Intersubunit β-Sheet Fibronectin Type III (FNIII) Dimer IMPLICATIONS FOR RECEPTOR ACTIVATION
Maria A. Schumacher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Pontus Bostroem et al.
NATURE (2012)
Insulin resistance in the nervous system
Bhumsoo Kim et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Contribution of systemic inflammation to chronic neurodegeneration
V. Hugh Perry
ACTA NEUROPATHOLOGICA (2010)
Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure
Jenna C. Carroll et al.
BRAIN RESEARCH (2010)
Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology
Manuela Polydoro et al.
JOURNAL OF NEUROSCIENCE (2009)
G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences
Franz Faul et al.
BEHAVIOR RESEARCH METHODS (2007)
Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns
Nilufer Esen et al.
JOURNAL OF IMMUNOLOGY (2006)
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROSCIENCE (2005)
Strategies and methods for research on sex differences in brain and behavior
JB Becker et al.
ENDOCRINOLOGY (2005)
Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease
D Panda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes
K Duff et al.
NEUROBIOLOGY OF DISEASE (2000)