相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Association between increased plasma ceramides and chronic kidney disease in patients with and without ischemic heart disease
A. Mantovani et al.
DIABETES & METABOLISM (2021)
Association between specific plasma ceramides and high-sensitivity C-reactive protein levels in postmenopausal women with type 2 diabetes
A. Mantovani et al.
DIABETES & METABOLISM (2020)
Risky lipids: refining the ceramide score that measures cardiovascular health
Annelise M. Poss et al.
EUROPEAN HEART JOURNAL (2020)
Development and variation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients
Mika Hilvo et al.
EUROPEAN HEART JOURNAL (2020)
Associations between specific plasma ceramides and severity of coronary-artery stenosis assessed by coronary angiography
A. Mantovani et al.
DIABETES & METABOLISM (2020)
Fenretinide treatment accelerates atherosclerosis development in apoE-deficient mice in spite of beneficial metabolic effects
Marco Busnelli et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response After Myocardial Infarction
Yoav Hadas et al.
CIRCULATION (2020)
Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease
Annelise M. Poss et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Ceramides and risk of major adverse cardiovascular events: A meta-analysis of longitudinal studies
Alessandro Mantovani et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2020)
The role of ceramides in metabolic disorders: when size and localization matters
Sarah M. Turpin-Nolan et al.
NATURE REVIEWS ENDOCRINOLOGY (2020)
Cellular and Molecular Differences between HFpEF and HFrEF: A Step Ahead in an Improved Pathological Understanding
Steven J. Simmonds et al.
CELLS (2020)
Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Plasma Ceramide Levels
Qian Ye et al.
AMERICAN JOURNAL OF CARDIOLOGY (2020)
Reign in the membrane: How common lipids govern mitochondrial function
Katsuhiko Funai et al.
CURRENT OPINION IN CELL BIOLOGY (2020)
Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes
Linda R. Peterson et al.
JOURNAL OF LIPID RESEARCH (2020)
Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction
Ali Javaheri et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)
Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy
Mika Hilvo et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)
Too Much of a Good Thing? An Evolutionary Theory to Explain the Role of Ceramides in NAFLD
Annelise M. Poss et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases
Suryaprakash Raichur
FRONTIERS IN ENDOCRINOLOGY (2020)
Transcription factors activated through RIP (regulated intramembrane proteolysis) and RAT (regulated alternative translocation)
Jin Ye
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
An adiponectin-S1P autocrine axis protects skeletal muscle cells from palmitate-induced cell death
Amy Botta et al.
LIPIDS IN HEALTH AND DISEASE (2020)
Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification
Mika Hilvo et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients
Mika Hilvo et al.
EUROPEAN HEART JOURNAL (2020)
An adiponectin-S1P axis protects against lipid induced insulin resistance and cardiomyocyte cell death via reduction of oxidative stress
Amy Botta et al.
NUTRITION & METABOLISM (2019)
An updated review of lipid-modifying therapy
Leon A. Simons
MEDICAL JOURNAL OF AUSTRALIA (2019)
Nitrosative stress drives heart failure with preserved ejection fraction
Gabriele G. Schiattarella et al.
NATURE (2019)
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondria! Fragmentation in Obesity
Philipp Hammerschmidt et al.
CELL (2019)
Plasma Ceramides and Sphingomyelins in Relation to Heart Failure Risk The Cardiovascular Health Study
Rozenn N. Lemaitre et al.
CIRCULATION-HEART FAILURE (2019)
Structure, functions and regulation of CERT, a lipid-transfer protein for the delivery of ceramide at the ER-Golgi membrane contact sites
Keigo Kumagai et al.
FEBS LETTERS (2019)
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
Bhagirath Chaurasia et al.
SCIENCE (2019)
Effect of Continuous-Flow Left Ventricular Assist Device Support on Coronary Artery Endothelial Function in Ischemic and Nonischemic Cardiomyopathy
J. David Symons et al.
CIRCULATION-HEART FAILURE (2019)
Vascular Endothelial Cell Biology: An Update
Anne Krueger-Genge et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation
You-Zhi Zhang et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2019)
Heart Failure in Type 2 Diabetes Mellitus Impact of Glucose-Lowering Agents, Heart Failure Therapies, and Novel Therapeutic Strategies
Helena C. Kenny et al.
CIRCULATION RESEARCH (2019)
The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach
Suryaprakash Raichur et al.
MOLECULAR METABOLISM (2019)
Intensive LDL cholesterol-lowering treatment beyond current recommendations for the prevention of major vascular events: a systematic review and meta-analysis of randomised trials including 327 037 participants
Nelson Wang et al.
Lancet Diabetes & Endocrinology (2019)
Metabolic Messengers: ceramides
Scott A. Summers et al.
NATURE METABOLISM (2019)
Bariatric Surgery-Induced Cardiac and Lipidomic Changes in Obesity-Related Heart Failure with Preserved Ejection Fraction
Deana Mikhalkova et al.
OBESITY (2018)
Plasma Ceramides: A Novel Predictor of Major Adverse Cardiovascular Events After Coronary Angiography
Jeffrey W. Meeusen et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)
Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study
Rozenn N. Lemaitre et al.
DIABETES (2018)
Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes
Brittany A. Law et al.
FASEB JOURNAL (2018)
Cardiac macrophages promote diastolic dysfunction
Maarten Hulsmans et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients
Sharda Anroedh et al.
JOURNAL OF LIPID RESEARCH (2018)
Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function
Zhiqiang Li et al.
CELL DEATH & DISEASE (2018)
Ceramide Remodeling and Risk of Cardiovascular Events and Mortality
Linda R. Peterson et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction
Connie W. Tsao et al.
JACC-HEART FAILURE (2018)
Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy
Alessandro Mantovani et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)
Circulating Very Long-Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study
Rozenn N. Lemaitre et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
Structural insights into adiponectin receptors suggest ceramidase activity
Ieva Vasiliauskaite-Brooks et al.
NATURE (2017)
AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia
Arwa Fairaq et al.
PHARMACOLOGICAL RESEARCH (2017)
The role of oxidative stress and NADPH oxidase in the pathogenesis of atherosclerosis
Dorota Bryk et al.
Postepy Higieny I Medycyny Doswiadczalnej (2017)
Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis
William L. Holland et al.
MOLECULAR METABOLISM (2017)
Increased de novo ceramide synthesis and accumulation in failing myocardium
Ruiping Ji et al.
JCI INSIGHT (2017)
Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation
Andreas Edsfeldt et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort
Aki S. Havulinna et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Inhibition of ceramide de novo synthesis as a postischemic strategy to reduce myocardial reperfusion injury
M. R. Reforgiato et al.
BASIC RESEARCH IN CARDIOLOGY (2016)
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol
Reijo Laaksonen et al.
EUROPEAN HEART JOURNAL (2016)
Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase
Michael J. Genin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix
Qiuyue Chen et al.
MOLECULAR CELL (2016)
Adiponectin, the past two decades
Zhao V. Wang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2016)
Understanding heart failure with preserved ejection fraction: where are we today?
L. van Heerebeek et al.
NETHERLANDS HEART JOURNAL (2016)
Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway
Ching-Han Lin et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2016)
Plasma concentrations of molecular lipid species in relation to coronary plaque characteristics and cardiovascular outcome: Results of the ATHEROREMO-IVUS study
Jin M. Cheng et al.
ATHEROSCLEROSIS (2015)
Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo
Leena P. Bharath et al.
DIABETES (2015)
Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy
Jason Newton et al.
EXPERIMENTAL CELL RESEARCH (2015)
Ceramide Synthase 4 Regulates Stem Cell Homeostasis and Hair Follicle Cycling
Franziska Peters et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis
Takhar Kasumov et al.
PLOS ONE (2015)
The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes
Nimesh Mody et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration
Trevor S. Tippetts et al.
BMC CARDIOVASCULAR DISORDERS (2014)
Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
Sarah M. Turpin et al.
CELL METABOLISM (2014)
C16:0-Ceramide Signals Insulin Resistance
Timothy Hla et al.
CELL METABOLISM (2014)
CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
Suryaprakash Raichur et al.
CELL METABOLISM (2014)
Heart Failure With Preserved Ejection Fraction Molecular Pathways of the Aging Myocardium
Francesco S. Loffredo et al.
CIRCULATION RESEARCH (2014)
Dose-Dependent Effects of Rosuvastatin on the Plasma Sphingolipidome and Phospholipidome in the Metabolic Syndrome
Theodore W. K. Ng et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin and PCSK9 Deficiency
Kirill Tarasov et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
METABOLIC COMORBIDITIES ASOCIATED WITH ENDOTHELIAL INFLAMMATION AND REDUCED NO-BIOAVALABILITY AS A NOVEL PARADIGM FOR HEART FAILURE WITH PRESERVED EJECTION FRACTION
Constantijn Franssen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease
Krzysztof Kurek et al.
LIVER INTERNATIONAL (2014)
Effect of Rosuvastatin on Repeat Heart Failure Hospitalizations The CORONA Trial (Controlled Rosuvastatin Multinational Trial in Heart Failure)
Jennifer K. Rogers et al.
JACC-HEART FAILURE (2014)
Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance-Related Endothelial Cell Dysfunction
Piruthivi Sukumar et al.
DIABETES (2013)
Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain
Hila Zigdon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Myristate-derived d16:0 Sphingolipids Constitute a Cardiac Sphingolipid Pool with Distinct Synthetic Routes and Functional Properties
Sarah Brice Russo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Increased Oxidative Stress Impairs Adipose Tissue Function in Sphingomyelin Synthase 1 Null Mice
Masato Yano et al.
PLOS ONE (2013)
Lipotoxicity contributes to endothelial dysfunction: A focus on the contribution from ceramide
J. David Symons et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2013)
Lipidomics Technologies at the End of the First Decade and the Beginning of the Next
Alfred H. Merrill et al.
ADVANCES IN NUTRITION (2013)
Autophagy and mitophagy in cellular damage control
Jianhua Zhang
REDOX BIOLOGY (2013)
Impact of Sphingomyelin Synthase 1 Deficiency on Sphingolipid Metabolism and Atherosclerosis in Mice
Zhiqiang Li et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Fenretinide Ameliorates Insulin Resistance and Fatty Liver in Obese Mice
In-uk Koh et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2012)
Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance, and Normalizes Cardiac Metabolism in Patients With Advanced Heart Failure
Aalap Chokshi et al.
CIRCULATION (2012)
Adipose Tissue Inflammation and Adiponectin Resistance in Patients With Advanced Heart Failure Correction After Ventricular Assist Device Implantation
Raffay S. Khan et al.
CIRCULATION-HEART FAILURE (2012)
Mechanisms of Lipotoxicity in the Cardiovascular System
Adam R. Wende et al.
CURRENT HYPERTENSION REPORTS (2012)
Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
Quan-Jiang Zhang et al.
DIABETES (2012)
Endothelial dysfunction and hypertension in aging
Yukihito Higashi et al.
HYPERTENSION RESEARCH (2012)
Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis
Benjamin T. Bikman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
Sarah Brice Russo et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Sphingomyelin synthase 2 over-expression induces expression of aortic inflammatory biomarkers and decreases circulating EPCs in ApoE KO mice
Ya-Rui Zhao et al.
LIFE SCIENCES (2012)
Inhibition of Serine Palmitoyl Transferase I Reduces Cardiac Ceramide Levels and Increases Glycolysis Rates following Diet-Induced Insulin Resistance
John R. Ussher et al.
PLOS ONE (2012)
Effects of Continuous-Flow Versus Pulsatile-Flow Left Ventricular Assist Devices on Myocardial Unloading and Remodeling
Tomoko S. Kato et al.
CIRCULATION-HEART FAILURE (2011)
Inhibition of ceramide synthesis reverses endothelial dysfunction and atherosclerosis in streptozotocin-induced diabetic rats
Li Chun et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2011)
Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice
Xiaogang Wang et al.
LIPIDS IN HEALTH AND DISEASE (2011)
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
William L. Holland et al.
NATURE MEDICINE (2011)
Selective Reduction in the Sphingomyelin Content of Atherogenic Lipoproteins Inhibits Their Retention in Murine Aortas and the Subsequent Development of Atherosclerosis
Yifan Fan et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
John R. Ussher et al.
DIABETES (2010)
Regulation of ceramide channels by Bcl-2 family proteins
Vidyaramanan Ganesan et al.
FEBS LETTERS (2010)
c-Myc Is a Nrf2-Interacting Protein that Negatively Regulates Phase II Genes Through Their Electrophile Responsive Elements
Smadar Levy et al.
IUBMB LIFE (2010)
A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS
Chris R. Triggle et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2010)
Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis
Frederic Preitner et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome
Guang Yang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
Ratnadeep Basu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Sphingomyelin Synthase 2 Is One of the Determinants for Plasma and Liver Sphingomyelin Levels in Mice
Jing Liu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol
Zhiqiang Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
CERT-mediated trafficking of ceramide
Kentaro Hanada et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
Sphingosine-1-phosphate receptor signalling in the heart
Christopher K. Means et al.
CARDIOVASCULAR RESEARCH (2009)
Protective effects of sphingosine-1-phosphate receptor agonist treatment after myocardial ischaemia-reperfusion
Ulrich Hofmann et al.
CARDIOVASCULAR RESEARCH (2009)
Sphingosine-1-phosphate and modulation of vascular tone
Junsuke Igarashi et al.
CARDIOVASCULAR RESEARCH (2009)
Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice
Jing Liu et al.
CIRCULATION RESEARCH (2009)
Targeting sphingosine-1-phosphate signalling for cardioprotection
Simon Kennedy et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Analysis of Development of Lesions in Mice with Serine Palmitoyltransferase (SPT) Deficiency-Sptlc2 Conditional Knockout Mice-
Etsuko Ohta et al.
EXPERIMENTAL ANIMALS (2009)
The SPTLC3 Subunit of Serine Palmitoyltransferase Generates Short Chain Sphingoid Bases
Thorsten Hornemann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Sphingosine protects aging hearts from ischemia/reperfusion injury Superiority to sphingosine 1-phosphate and ischemic pre- and post-conditioning
Donald A. Vessey et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2009)
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities
Gongshe Han et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Combined sphingosine, S1P and ischemic postconditioning rescue the heart after protracted ischemia
Donald A. Vessey et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer
Harriet Johansson et al.
CANCER RESEARCH (2008)
Vascular endothelium as a contributor of plasma sphingosine 1-phosphate
Krishnan Venkataraman et al.
CIRCULATION RESEARCH (2008)
\Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphate
Donald A. Vessey et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2008)
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy
Tae-Sik Park et al.
JOURNAL OF LIPID RESEARCH (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Characterization of ceramide synthase 2 - Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
Elad L. Laviad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration
Elias N. Glaros et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
William L. Holland et al.
CELL METABOLISM (2007)
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
Peter F. Mount et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice
Tae-Sik Park et al.
ATHEROSCLEROSIS (2006)
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A
Anthony R. Smith et al.
AGING CELL (2006)
Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice
Jibin Dong et al.
JOURNAL OF LIPID RESEARCH (2006)
Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice
MR Hojjati et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2005)
Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice
MR Hojjati et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Ceramide-induced impairment of endothelial function is prevented by CuZn superoxide dismutase overexpression
SP Didion et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice
TS Park et al.
CIRCULATION (2004)
DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine
F Omae et al.
BIOCHEMICAL JOURNAL (2004)
Sphingosine 1-phosphate and control of vascular tone
APV Dantas et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Ceramide-induced activation of NADPH oxidase and endothelial dysfunction in small coronary arteries
DX Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Dual effect of ceramide on human endothelial cells -: Induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase
HG Li et al.
CIRCULATION (2002)
The ceramide-centric universe of lipid-mediated cell regulation: Stress encounters of the lipid kind.
YA Hannun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
De novo sphingolipid biosynthesis:: A necessary, but dangerous, pathway.
AH Merrill
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide the A549 human lung adenocarcinoma cell line - Role for endogenous ceramide in mediating the action of exogenous ceramide
B Ogretmen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Enzymes of sphingolipid metabolism: From modular to integrative signaling
YA Hannun et al.
BIOCHEMISTRY (2001)
Fatty acid-induced apoptosis in neonatal cardiomyocytes: Redox signaling
GC Sparagna et al.
ANTIOXIDANTS & REDOX SIGNALING (2001)
Plasma sphingomyelin level as a risk factor for coronary artery disease
XC Jiang et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis
GC Sparagna et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Ceramide interaction with the respiratory chain of heart mitochondria
M Di Paola et al.
BIOCHEMISTRY (2000)
Sphingomyelinase and ceramide analogs induce contraction and rises in [Ca2+]i in canine cerebral vascular muscle
T Zheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes
DLM Hickson-Bick et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)
分享论文
