Lymphoid stromal cells proGrem dendritic cell homeostasis

Single-cell technologies reveal the building blocks of secondary lymphoid organs, identifying Grem1(+) fibroblastic reticular cells (FRCs) as critical niche cells that contribute to resident dendritic cell homeostasis and T cell immunity.

Automated summary

Single-cell technologies have revealed the critical role of Grem1(+) fibroblastic reticular cells (FRCs) as niche cells in secondary lymphoid organs, contributing to the homeostasis of resident dendritic cells and T cell immunity.