期刊
MOLECULES
卷 26, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/molecules26103038
关键词
Chrysanthemum genus; sesquiterpenoids; biosynthetic pathway; pharmacological effects
资金
- National Natural Science Foundation of China [81874369]
- Natural Science Foundation of Hunan Province [2020JJ4064]
- Pharmaceutical Open Fund of Domestic First-Class Disciplines (cultivation) of Hunan Province [2020YX10]
- Changsha Municipal Natural Science Foundation [kq2014086]
Research on sesquiterpenoids obtained from the Chrysanthemum genus has shown their potential biological activities, including anti-inflammatory, antibacterial, and antitumor effects, providing a scientific basis for their future development and utilization.
Plants from the Chrysanthemum genus are rich sources of chemical diversity and, in recent years, have been the focus of research on natural products chemistry. Sesquiterpenoids are one of the major classes of chemical constituents reported from this genus. To date, more than 135 sesquiterpenoids have been isolated and identified from the whole genus. These include 26 germacrane-type, 26 eudesmane-type, 64 guaianolide-type, 4 bisabolane-type, and 15 other-type sesquiterpenoids. Pharmacological studies have proven the biological potential of sesquiterpenoids isolated from Chrysanthemum species, reporting anti-inflammatory, antibacterial, antitumor, insecticidal, and antiviral activities for these interesting molecules. In this paper, we provide information on the chemistry and bioactivity of sesquiterpenoids obtained from the Chrysanthemum genus which could be used as the scientific basis for their future development and utilization.
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