期刊
MOLECULES
卷 26, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/molecules26082215
关键词
Acanthopanax henryi; Eleutherococcus henryi; botany; phytochemistry; pharmacology; biological activities
资金
- Jiangxi Provincial Natural Science Foundation [20202BABL216070]
- Jiangxi Provincial Department of Education [GJJ201538]
- Gannan Medical University [QD201905, ZD201911, YB201910]
- Hunan Provincial Natural Science Foundation [2019JJ40223]
Acanthopanax henryi is a widely used traditional Chinese herb with various effects, mainly attributed to its triterpenoid saponins. Recent studies have shown its pharmacological activities including anti-inflammatory, anti-cancer, and antioxidant effects.
Acanthopanax henryi (Oliv.) Harms (Araliaceae), also known as Eleutherococcus henryi and Caoyewujia (Hengliwujia) in Chinese, is a widely used traditional Chinese herb with the effects of expelling wind and removing dampness, relaxing the muscles and stimulating the blood circulation, and regulating the flow of qi to alleviate pain in the theory of Traditional Chinese Medicine. Acanthopanax henryi (AH, thereafter) possesses ginseng-like activities and is known as ginseng-like herb. In the past decade, a great number of phytochemical and pharmacological studies on AH have been carried out. Several kinds of chemical compositions have been reported, including terpenoids (monoterpenoids, diterpenoids, and triterpenoid saponins), phenylpropanoids, caffeoyl quinic acid derivatives, flavonoids, lignans, sterols, fatty acids, etc., among which, triterpenoid saponins were considered to be the most active components. Considerable pharmacological experiments in vitro have demonstrated that AH possessed anti-neuroinflammatory, anti-adipogenic, anti-inflammatory, antibacterial, anti-cancer, anti-oxidation, anti-AChE, anti-BuChE, and antihyaluronidase activities. The present review is an up-to-date and comprehensive analysis of the botany, phytochemistry, and pharmacology of AH.
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