相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence
Zhu Wang et al.
ONCOGENE (2020)
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
Leiming Wang et al.
SCIENCE ADVANCES (2020)
Nuclear receptor ERRα contributes to castration-resistant growth of prostate cancer via its regulation of intratumoral androgen biosynthesis
Zhenyu Xu et al.
THERANOSTICS (2020)
Targeting the androgen receptor and overcoming resistance in prostate cancer
David J. Einstein et al.
CURRENT OPINION IN ONCOLOGY (2019)
BI1071, a Novel Nur77 Modulator, Induces Apoptosis of Cancer Cells by Activating the Nur77-Bcl-2 Apoptotic Pathway
Xiaohui Chen et al.
MOLECULAR CANCER THERAPEUTICS (2019)
THE ORPHAN NUCLEAR RECEPTORS STEROIDOGENIC FACTOR-1 AND LIVER RECEPTOR HOMOLOG-1: STRUCTURE, REGULATION, AND ESSENTIAL ROLES IN MAMMALIAN REPRODUCTION
Marie-Charlotte Meinsohn et al.
PHYSIOLOGICAL REVIEWS (2019)
Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a de novo low AR-Active Subclass in Treatment Naive Primary Prostate Cancer
Daniel E. Spratt et al.
CLINICAL CANCER RESEARCH (2019)
Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence
Hong Sheng Cheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Xinming Jing et al.
MOLECULAR CANCER (2019)
The dynamic nature of senescence in cancer
Soyoung Lee et al.
NATURE CELL BIOLOGY (2019)
Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer
Veronica Mollica et al.
CELLS (2019)
Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer
Elahe A. Mostaghel et al.
CLINICAL CANCER RESEARCH (2019)
Clonal Evolution and Epithelial Plasticity in the Emergence of AR-Independent Prostate Carcinoma
Sara Laudato et al.
TRENDS IN CANCER (2019)
Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer
Zhu Wang et al.
ENDOCRINE-RELATED CANCER (2018)
Aberrant expression of miR-141 and nuclear receptor small heterodimer partner in clinical samples of prostate cancer
Maryam Khorasani et al.
CANCER BIOMARKERS (2018)
Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis
Lijia Xiao et al.
CANCER RESEARCH (2018)
Global, Regional and National Burden of Prostate Cancer, 1990 to 2015: Results from the Global Burden of Disease Study 2015
Farhad Pishgar et al.
JOURNAL OF UROLOGY (2018)
Cellular plasticity and the neuroendocrine phenotype in prostate cancer
Alastair H. Davies et al.
NATURE REVIEWS UROLOGY (2018)
Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription
Lin Jia et al.
ONCOGENE (2018)
Recent advances on the progressive mechanism and therapy in castration-resistant prostate cancer
Keshan Wang et al.
ONCOTARGETS AND THERAPY (2018)
Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells
Martin C. Pearce et al.
Oncotarget (2018)
The nuclear receptor superfamily: A structural perspective
Emily R. Weikum et al.
PROTEIN SCIENCE (2018)
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses
Qiuhui Li et al.
NATURE COMMUNICATIONS (2018)
Castration-Resistant Prostate Cancer Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents: Opportunities and Challenges
Yuki Kita et al.
CANCERS (2018)
NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients
Elin Borgen et al.
BREAST CANCER RESEARCH (2018)
Cancer stem cells revisited
Eduard Batlle et al.
NATURE MEDICINE (2017)
Emerging Variants of Castration-Resistant Prostate Cancer
Panagiotis J. Vlachostergios et al.
CURRENT ONCOLOGY REPORTS (2017)
Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer
Howard I. Scher et al.
CANCER RESEARCH (2017)
Targeting androgen-independent pathways: new chances for patients with prostate cancer?
C. Cattrini et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2017)
Mechanisms of resistance to systemic therapy in metastatic castration-resistant prostate cancer
Giuseppe Galletti et al.
CANCER TREATMENT REVIEWS (2017)
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
Giuseppa Pistritto et al.
AGING-US (2016)
Cancer Stem Cells: Basic Concepts and Therapeutic Implications
Dany Nassar et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)
Prostate Cancer Stem Cells: Viewing Signaling Cascades at a Finer Resolution
Xiukun Lin et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2016)
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Himisha Beltran et al.
NATURE MEDICINE (2016)
Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer
Shih-Chieh Lin et al.
NATURE COMMUNICATIONS (2016)
MPC1, a key gene in cancer metabolism, is regulated by COUP-TFII in human prostate cancer
Leiming Wang et al.
ONCOTARGET (2016)
NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress
Judith Alonso et al.
SCIENTIFIC REPORTS (2016)
TLX: A master regulator for neural stem cell maintenance and neurogenesis
Mohammed M. Islam et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
The hallmarks of castration-resistant prostate cancers
Maria Katsogiannou et al.
CANCER TREATMENT REVIEWS (2015)
Poly r(C) Binding Protein-1 is Central to Maintenance of Cancer Stem Cells in Prostate Cancer Cells
Qi Chen et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer
Jordan A. Beard et al.
CELLULAR SIGNALLING (2015)
Hypoxia and Prostate Cancer Aggressiveness: A Tale With Many Endings
Avelino Fraga et al.
CLINICAL GENITOURINARY CANCER (2015)
Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy
Erik Hedrick et al.
ENDOCRINE-RELATED CANCER (2015)
Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions
Avi Ashkenazi
JOURNAL OF CLINICAL INVESTIGATION (2015)
Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1/CIP1) and SIRT1 genes
Dinglan Wu et al.
JOURNAL OF PATHOLOGY (2015)
Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC)
Trevor M. Penning
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
TR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene Expression
Jin Zhu et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Regulation of Steroidogenesis, Development, and Cell Differentiation by Steroidogenic Factor-1 and Liver Receptor Homolog-1
Takashi Yazawa et al.
ZOOLOGICAL SCIENCE (2015)
NR2F1 controls tumour cell dormancy via SOX9-and RAR beta-driven quiescence programmes
Maria Soledad Sosa et al.
NATURE COMMUNICATIONS (2015)
Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors
Eddy J. Chen et al.
CLINICAL CANCER RESEARCH (2015)
Emerging Roles of Orphan Nuclear Receptors in Cancer
Sung Hee Baek et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 76 (2014)
NR4A nuclear receptors are orphans but not lonesome
Kondababu Kurakula et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
The role of testicular nuclear receptor 4 in chemo-resistance of docetaxel in castration-resistant prostate cancer
B. Chen et al.
CANCER GENE THERAPY (2014)
Novel Polymeric Nanoparticles for Intracellular Delivery of Peptide Cargos: Antitumor Efficacy of the BCL-2 Conversion Peptide NuBCP-9
Manoj Kumar et al.
CANCER RESEARCH (2014)
Orphan nuclear receptors as drug targets for the treatment of prostate and breast cancers
Mani Roshan-Moniri et al.
CANCER TREATMENT REVIEWS (2014)
Steroidogenic Factor 1 Promotes Aggressive Growth of Castration-Resistant Prostate Cancer Cells by Stimulating Steroid Synthesis and Cell Proliferation
Samantha R. Lewis et al.
ENDOCRINOLOGY (2014)
ERRα augments HIF-1 signalling by directly interacting with HIF-1α in normoxic and hypoxic prostate cancer cells
Chang Zou et al.
JOURNAL OF PATHOLOGY (2014)
Minireview: Role Of Orphan Nuclear Receptors in Cancer and Potential as Drug Targets
Stephen Safe et al.
MOLECULAR ENDOCRINOLOGY (2014)
Prostate Stromal Cells Express the Progesterone Receptor to Control Cancer Cell Mobility
Yue Yu et al.
PLOS ONE (2014)
microRNA-181 promotes prostate cancer cell proliferation by regulating DAX-1 expression
Shi-Jun Tong et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2014)
The critical roles of COUP-TFII in tumor progression and metastasis
Jun Qin et al.
CELL AND BIOSCIENCE (2014)
Targeting the Apoptosis Pathway in Prostate Cancer
Robert R. Zielinski et al.
CANCER JOURNAL (2013)
Increased expression of activated endothelial nitric oxide synthase contributes to antiandrogen resistance in prostate cancer cells by suppressing androgen receptor transactivation
Shan Yu et al.
CANCER LETTERS (2013)
Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
Vivek K. Arora et al.
CELL (2013)
Increased Chemosensitivity via Targeting Testicular Nuclear Receptor 4 (TR4)-Oct4-Interleukin 1 Receptor Antagonist (IL1Ra) Axis in Prostate Cancer CD133+ Stem/Progenitor Cells to Battle Prostate Cancer
Dong-Rong Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Expression and Function of the Progesterone Receptor in Human Prostate Stroma Provide Novel Insights to Cell Proliferation Control
Yue Yu et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
The orphan nuclear receptors at their 25-year reunion
Shannon E. Mullican et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2013)
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis
Jun Qin et al.
NATURE (2013)
Regulatory potential of COUP-TFs in development: Stem/progenitor cells
Xin Xie et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2013)
The prognostic significance of loss of the androgen receptor and neuroendocrine differentiation in prostate biopsy specimens among castration-resistant prostate cancer patients
Akira Komiya et al.
MOLECULAR AND CLINICAL ONCOLOGY (2013)
The PSA-/Io Prostate Cancer Cell Population Harbors Self-Renewing Long-Term Tumor-Propagating Cells that Resist Castration
Jichao Qin et al.
CELL STEM CELL (2012)
Multiple roles of COUP-TFII in cancer initiation and progression
Lacey M. Litchfield et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2012)
Ligand-independent actions of the orphan receptors/corepressors DAX-1 and SHP in metabolism, reproduction and disease
Anna Ehrlund et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2012)
Androgen receptor (AR) aberrations in castration-resistant prostate cancer
Kati K. Waltering et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ
Ja Hee Lee et al.
PLOS ONE (2012)
Genome-Wide Analysis of Androgen Receptor Targets Reveals COUP-TF1 as a Novel Player in Human Prostate Cancer
Ruth Perets et al.
PLOS ONE (2012)
Serum/glucocorticoid-regulated kinase 1 expression in primary human prostate cancers
Russell Z. Szmulewitz et al.
PROSTATE (2012)
miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein
Jing Xiao et al.
PROSTATE (2012)
Role of nuclear receptor SHP in metabolism and cancer
Yuxia Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
Changmeng Cai et al.
CANCER CELL (2011)
Coup d'Etat: An Orphan Takes Control
Fu-Jung Lin et al.
ENDOCRINE REVIEWS (2011)
Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy
Changmeng Cai et al.
ENDOCRINE-RELATED CANCER (2011)
Nuclear Orphan Receptor TLX Induces Oct-3/4 for the Survival and Maintenance of Adult Hippocampal Progenitors upon Hypoxia
Pavithra Lakshminarasimhan Chavali et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Androgen Receptors Are Differentially Expressed in Gleason Patterns of Prostate Cancer and Down-Regulated in Matched Lymph Node Metastases
Achim Fleischmann et al.
PROSTATE (2011)
Integrative Genomic Profiling of Human Prostate Cancer
Barry S. Taylor et al.
CANCER CELL (2010)
SnapShot: Extrinsic Apoptosis Pathways
Inge Verbrugge et al.
CELL (2010)
The senescence pathway in prostatic carcinogenesis
Sowmya Sharma et al.
PATHOLOGY (2010)
The Nuclear Orphan Receptor COUP-TFII Plays an Essential Role in Adipogenesis, Glucose Homeostasis, and Energy Metabolism
Luoping Li et al.
CELL METABOLISM (2009)
WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
Isabelle Bisson et al.
CELL RESEARCH (2009)
Nuclear Receptor DAX1 in Human Prostate Cancer: A Novel Independent Biological Modulator
Yasuhiro Nakamura et al.
ENDOCRINE JOURNAL (2009)
Phase 1 Trial of High-Dose Exogenous Testosterone in Patients with Castration-Resistant Metastatic Prostate Cancer
Michael J. Morris et al.
EUROPEAN UROLOGY (2009)
Genomic Strategy for Targeting Therapy in Castration-Resistant Prostate Cancer
Prateek Mendiratta et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
Siva Kumar Kolluri et al.
CANCER CELL (2008)
Hypoxia in prostate cancer: A powerful shield against tumour destruction?
L. Marignol et al.
CANCER TREATMENT REVIEWS (2008)
Nur77 upregulates HIF-α by inhibiting pVHL-mediated degradation
Bu-Yeon Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2008)
Orphan nuclear receptor estrogen-related receptor-β suppresses in vitro and in vivo growth of prostate cancer cells via p21WAF1/CIP1 induction and as a potential therapeutic target in prostate cancer
S. Yu et al.
ONCOGENE (2008)
Identification of the first synthetic steroidogenic factor 1 inverse agonists: Pharmacological modulation of steroidogenic enzymes
Andria L. Del Tredici et al.
MOLECULAR PHARMACOLOGY (2008)
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
GuoQiang Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3
Kuk-Wha Lee et al.
CARCINOGENESIS (2007)
Bcl-2 and Bax expression predict prostate cancer outcome in men treated with androgen deprivation and radiotherapy on Radiation Therapy Oncology Group protocol 92-02
Li Yan Khor et al.
CLINICAL CANCER RESEARCH (2007)
An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: Effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity
Marcia I. Dawson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
ERR-γ suppresses cell proliferation and tumor growth of androgen-sensitive and androgen-insensitive prostate cancer cells and its implication as a therapeutic target for prostate cancer
Shan Yu et al.
CANCER RESEARCH (2007)
Opinion - How many drug targets are there?
John P. Overington et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1
Chun-Li Zhang et al.
GENES & DEVELOPMENT (2006)
Apoptosis evasion: The role of survival pathways in prostate cancer progression and therapeutic resistance
S McKenzie et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
SHP represses transcriptional activity via recruitment of histone deacetylases
J Gobinet et al.
BIOCHEMISTRY (2005)
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
BZ Lin et al.
CELL (2004)
Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1α
YG Yoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis
N Ke et al.
CANCER RESEARCH (2004)
Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor α
BB Busch et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
TR3 orphan nuclear receptor mediates apoptosis through up-regulating E2F1 in human prostate cancer LNCaP cells
XM Mu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3
XM Mu et al.
PROSTATE (2003)
Repressors of androgen and progesterone receptor action
IU Agoulnik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells
SK Kolluri et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion
CL Olsen et al.
ONCOGENE (2002)
Hypoxia - A key regulatory factor in tumour growth
AL Harris
NATURE REVIEWS CANCER (2002)
Characterization of the interaction between androgen receptor and a new transcriptional inhibitor, SHP
J Gobinet et al.
BIOCHEMISTRY (2001)
Lack of replicative senescence in cultured rat - Oligodendrocyte precursor cells
DG Tang et al.
SCIENCE (2001)
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
H Li et al.
SCIENCE (2000)
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor
XY Zhao et al.
NATURE MEDICINE (2000)
The prostate: Development and physiology
SW Hayward et al.
RADIOLOGIC CLINICS OF NORTH AMERICA (2000)