相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Autophagy in intracellular bacterial infection
Wei Hu et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
Phosphoproteomic Approaches to Discover Novel Substrates of Mycobacterial Ser/Thr Protein Kinases
Seanantha S. Baros et al.
MOLECULAR & CELLULAR PROTEOMICS (2020)
Silver Nanoparticles for the Therapy of Tuberculosis
Alexandru-Flaviu Tabaran et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)
Long-range replica exchange molecular dynamics guided drug repurposing against tyrosine kinase PtkA of Mycobacterium tuberculosis
Priya Nagpal et al.
SCIENTIFIC REPORTS (2020)
Metformin as Host-Directed Therapy for TB Treatment: Scoping Review
Nikita Naicker et al.
FRONTIERS IN MICROBIOLOGY (2020)
Expression and purification of soluble recombinant SapM from Mycobacterium tuberculosis
Paulina Fernandez-Soto et al.
PROTEIN EXPRESSION AND PURIFICATION (2020)
High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity AgainstMycobacterium tuberculosis
Tirosh Shapira et al.
FRONTIERS IN MICROBIOLOGY (2020)
Mycogenic Metal Nanoparticles for the Treatment of Mycobacterioses
Marta Filipa Simoes et al.
ANTIBIOTICS-BASEL (2020)
Sirtuin inhibits M. tuberculosis -induced apoptosis in macrophage through glycogen synthase kinase-3β
Hong Yang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2020)
New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach
Magdalena Gil et al.
JOURNAL OF PROTEOMICS (2019)
An Overview on the Potential Antimycobacterial Agents Targeting Serine/Threonine Protein Kinases from Mycobacterium tuberculosis
Matteo Mori et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2019)
Reactive species and pathogen antioxidant networks during phagocytosis
Lucia Piacenza et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects
Ekta Lachmandas et al.
JOURNAL OF INFECTIOUS DISEASES (2019)
The Isoniazid Paradigm of Killing, Resistance, and Persistence in Mycobacterium tuberculosis
Catherine Vilcheze et al.
JOURNAL OF MOLECULAR BIOLOGY (2019)
Evaluation of Xpert MTB-RIF guided diagnosis and treatment of rifampicin-resistant tuberculosis in Indonesia: A retrospective cohort study
Arto Yuwono Soeroto et al.
PLOS ONE (2019)
Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial
Chandrasekaran Padmapriyadarsini et al.
BMJ OPEN (2019)
The role of low molecular weight thiols in Mycobacterium tuberculosis
C. Sao Emani et al.
TUBERCULOSIS (2019)
NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G
Saqib Kidwai et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
Pauline Fernandez-Soto et al.
SCIENTIFIC REPORTS (2019)
Effects of Levofloxacin on Blood Lymphocyte Apoptosis in Patients with Pulmonary Tuberculosis: an In Vitro Study
V. A. Serebryakova et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2019)
Linezolid for drug-resistant pulmonary tuberculosis
Bhagteshwar Singh et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2019)
PknG supports mycobacterial adaptation in acidic environment
Ruchi Paroha et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2018)
Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery
Adrian Richter et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Vitamin C Potentiates the Killing of Mycobacterium tuberculosis by the First-Line Tuberculosis Drugs Isoniazid and Rifampin in Mice
Catherine Vilcheze et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Gamma-glutamylcysteine protects ergothioneine-deficient Mycobacterium tuberculosis mutants against oxidative and nitrosative stress
C. Sao Emani et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Host Directed Therapies for Tuberculosis: Futures Strategies for an Ancient Disease
Ivana Palucci et al.
CHEMOTHERAPY (2018)
Targeting the messengers: Serine/threonine protein kinases as potential targets for antimycobacterial drug development
Mehak Zahoor Khan et al.
IUBMB LIFE (2018)
Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies
Simon Tiberi et al.
LANCET INFECTIOUS DISEASES (2018)
The discovery of nitro-fatty acids as products of metabolic and inflammatory reactions and mediators of adaptive cell signaling
Bruce A. Freeman et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2018)
Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials
Cornelis J. Korbee et al.
NATURE COMMUNICATIONS (2018)
Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages
Dennis Wong et al.
SCIENTIFIC REPORTS (2018)
Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells
Marilena P. Etna et al.
PLOS PATHOGENS (2018)
The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation
Katelyn E. Zulauf et al.
PLOS PATHOGENS (2018)
Identification of Novel Mycobacteria Inhibitors Against Mycobacterial Protein Kinase G
Yuichi Kanehiro et al.
FRONTIERS IN MICROBIOLOGY (2018)
A Beneficial Effect of Low-Dose Aspirin in a Murine Model of Active Tuberculosis
Vera Marie Kroesen et al.
FRONTIERS IN IMMUNOLOGY (2018)
Mycobacterial PknG Targets the Rab711 Signaling Pathway To Inhibit Phagosome-Lysosome Fusion
Gourango Pradhan et al.
JOURNAL OF IMMUNOLOGY (2018)
An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria
Nabanita Bhattacharyya et al.
MBIO (2018)
The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis
C. Sao Emani et al.
JOURNAL OF BIOMEDICAL SCIENCE (2018)
Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions
Mehak Zahoor Khan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Mechanism of the Nitric Oxide Dioxygenase Reaction of Mycobacterium tuberculosis Hemoglobin N
Lavinia A. Carabet et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2017)
Aminorifannycins and Sporalactams Produced in Culture by a Micromonospora sp Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics
David E. Williams et al.
ORGANIC LETTERS (2017)
Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis
Catherine Vilcheze et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Sclerotiorin inhibits protein kinase G from Mycobacterium tuberculosis and impairs mycobacterial growth in macrophages
Dongni Chen et al.
TUBERCULOSIS (2017)
AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C
Chui Fann Wong et al.
SCIENTIFIC REPORTS (2017)
M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1
Murugesan V. S. Rajaram et al.
CELL REPORTS (2017)
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
Barbara Rieck et al.
PLOS PATHOGENS (2017)
The Macrophage: A Disputed Fortress in the Battle against Mycobacterium tuberculosis
Christophe J. Queval et al.
FRONTIERS IN MICROBIOLOGY (2017)
Saxifragifolin D attenuates phagosome maturation arrest in Mycobacterium tuberculosis-infected macrophages via an AMPK and VPS34-dependent pathway
Jia Zhou et al.
AMB EXPRESS (2017)
Non-Steroidal Anti-inflammatory Drugs As Host-Directed Therapy for Tuberculosis: A Systematic Review
Vera M. Kroesen et al.
FRONTIERS IN IMMUNOLOGY (2017)
Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed
Matthew F. Wipperman et al.
SCIENTIFIC REPORTS (2017)
Host-Directed Therapeutic Strategies for Tuberculosis
Afsal Kolloli et al.
FRONTIERS IN MEDICINE (2017)
Host-directed therapies offer novel opportunities for the fight against tuberculosis
Arnaud Machelart et al.
DRUG DISCOVERY TODAY (2017)
Role of apoptosis and autophagy in tuberculosis
Adam Lam et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2017)
ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
Jacques Augenstreich et al.
CELLULAR MICROBIOLOGY (2017)
Thymoquinone (TQ) inhibits the replication of intracellular Mycobacterium tuberculosis in macrophages and modulates nitric oxide production
Hafij Al Mahmud et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)
Modulation of host cell apoptotic pathways by intracellular pathogens
Anja Friedrich et al.
CURRENT OPINION IN MICROBIOLOGY (2017)
Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages
Flavia Sorrentino et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Loperamide Restricts Intracellular Growth of Mycobacterium tuberculosis in Lung Macrophages
Esmeralda Juarez et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions
Eduardo P. Amaral et al.
BMC MICROBIOLOGY (2016)
Dual-Reporter Mycobacteriophages (Φ2DRMs) Reveal Preexisting Mycobacterium tuberculosis Persistent Cells in Human Sputum
Paras Jain et al.
MBIO (2016)
Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense
Kan Lin et al.
PLOS PATHOGENS (2016)
Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen
Noton K. Dutta et al.
ACS INFECTIOUS DISEASES (2016)
Phosphorylation of Mycobacterium tuberculosis protein tyrosine kinase A PtkA by Ser/Thr protein kinases
Peifu Zhou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems
Subhalaxmi Nambi et al.
CELL HOST & MICROBE (2015)
Autophagy in the Fight Against Tuberculosis
Carla F. Bento et al.
DNA AND CELL BIOLOGY (2015)
Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis
Zakaria Hmama et al.
IMMUNOLOGICAL REVIEWS (2015)
Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity
Melissa Richard-Greenblat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Autophagy is not the answer
Samuel M. Behar et al.
NATURE (2015)
New potential eukaryotic substrates of the mycobacterial protein tyrosine phosphatase PtpA: hints of a bacterial modulation of macrophage bioenergetics state
Mariana Margenat et al.
SCIENTIFIC REPORTS (2015)
Host-Directed Therapies for Tuberculosis
David M. Tobin
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion
Mark Schiebler et al.
EMBO MOLECULAR MEDICINE (2015)
Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages
Pallavi Chandra et al.
SCIENTIFIC REPORTS (2015)
Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms
Valerie Poirier et al.
MICROBIOLOGY SPECTRUM (2015)
Rifampin Induces Hydroxyl Radical Formation in Mycobacterium tuberculosis
Giovanni Piccaro et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis
C. J. Cambier et al.
CELL (2014)
Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector
Aniek D. van der Woude et al.
CELLULAR MICROBIOLOGY (2014)
The thioredoxin antioxidant system
Jun Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Mycobacterium tuberculosis Promotes Anti-apoptotic Activity of the Macrophage by PtpA Protein-dependent Dephosphorylation of Host GSK3α
Valerie Poirier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Metformin as adjunct antituberculosis therapy
Amit Singhal et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth
Sarah A. Stanley et al.
PLOS PATHOGENS (2014)
Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center
Magdalena Gil et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion
Henning J. Kleine Balderhaar et al.
JOURNAL OF CELL SCIENCE (2013)
RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson's Disease Risk
David A. MacLeod et al.
NEURON (2013)
Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products
Alessandra Mascarello et al.
PLOS ONE (2013)
Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development
Dennis Wong et al.
TRENDS IN MICROBIOLOGY (2013)
Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
Robert O. Watson et al.
CELL (2012)
Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
Jwa-Jin Kim et al.
CELL HOST & MICROBE (2012)
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
Diane Houben et al.
CELLULAR MICROBIOLOGY (2012)
PAMPs and DAMPs: signal 0s that spur autophagy and immunity
Daolin Tang et al.
IMMUNOLOGICAL REVIEWS (2012)
Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of Mycobacterium tuberculosis in Human Macrophages
Heiko Bruns et al.
JOURNAL OF IMMUNOLOGY (2012)
The fbpA/sapM Double Knock Out Strain of Mycobacterium tuberculosis Is Highly Attenuated and Immunogenic in Macrophages
Sankaralingam Saikolappan et al.
PLOS ONE (2012)
The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence
Rachel E. Butler et al.
PLOS ONE (2012)
Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis
Ruth J. Napier et al.
CELL HOST & MICROBE (2011)
Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants
Philong Ta et al.
JOURNAL OF BACTERIOLOGY (2011)
Host-pathogen interactions Cell death and infection: A double-edged sword for host and pathogen survival
Hiroshi Ashida et al.
JOURNAL OF CELL BIOLOGY (2011)
Discovery and Structure-Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors
Jean-Damien Charrier et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway
Hun-Jung Park et al.
MOLECULAR IMMUNOLOGY (2011)
Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis
S. M. Behar et al.
MUCOSAL IMMUNOLOGY (2011)
Lysine Auxotrophy Combined with Deletion of the SecA2 Gene Results in a Safe and Highly Immunogenic Candidate Live Attenuated Vaccine for Tuberculosis
Joseph Hinchey et al.
PLOS ONE (2011)
Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1-and Cathepsin B-Independent Necrosis
Amanda Welin et al.
PLOS ONE (2011)
Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification
Dennis Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Signalling mechanisms in Mycobacteria
Pradip K. Chakraborti et al.
TUBERCULOSIS (2011)
Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: Kinetics, molecular modeling, toxicity and effect on growth
Alessandra Mascarello et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability
Martin Gengenbacher et al.
MICROBIOLOGY-SGM (2010)
Mycobacterium tuberculosis PtkA is a novel protein tyrosine kinase whose substrate is PtpA
Horacio Bach et al.
BIOCHEMICAL JOURNAL (2009)
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA
Katherine A. Rawls et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection
J. Muse Davis et al.
CELL (2009)
Key Residues in Mycobacterium tuberculosis Protein Kinase G Play a Role in Regulating Kinase Activity and Survival in the Host
Divya Tiwari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
New anti-tuberculosis agents amongst known drugs
Kathryn E. A. Lougheed et al.
TUBERCULOSIS (2009)
Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B
Horacio Bach et al.
CELL HOST & MICROBE (2008)
Signalling Inhibitors Against Mycobacterium tuberculosis - Early Days of a New Therapeutic Concept in Tuberculosis
B. Hegymegi-Barakonyi et al.
CURRENT MEDICINAL CHEMISTRY (2008)
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
Sonya D. Zabludoff et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Regulation of glutamate metabolism by protein kinases in mycobacteria
Helen M. O'Hare et al.
MOLECULAR MICROBIOLOGY (2008)
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis
Catherine Vilcheze et al.
MOLECULAR MICROBIOLOGY (2008)
PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release
Ramandeep Singh et al.
SCIENCE (2008)
Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages
R. Andres Floto et al.
AUTOPHAGY (2007)
T helper 2 Cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis
James Harris et al.
IMMUNITY (2007)
Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis
Nicole Scherr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin
Rajesh Jayachandran et al.
CELL (2007)
Modulation of gamma interferon receptor 1 by Mycobacterium tuberculosis:: a potential immune response evasive mechanism
Amit Singhal et al.
INFECTION AND IMMUNITY (2007)
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
Lea Fialkow et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Mycothiol-dependent proteins in actinomycetes
Mamta Rawat et al.
FEMS MICROBIOLOGY REVIEWS (2007)
Mycobacterium avium subsp paratuberculosis PtpA is an endogenous tyrosine phosphatase secreted during infection
Horacio Bach et al.
INFECTION AND IMMUNITY (2006)
Higher order Rab programming in phagolysosome biogenesis
Esteban A. Roberts et al.
JOURNAL OF CELL BIOLOGY (2006)
Mycothiol-dependent mycobacterial response to oxidative stress
Korine S. E. Ung et al.
FEBS LETTERS (2006)
Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism
V Deretic et al.
CELLULAR MICROBIOLOGY (2006)
In vitro properties of antimicrobial bromotyrosine alkaloids
N Pick et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2006)
Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness
S Matsubara et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)
The thiol-based redox networks of pathogens: Unexploited targets in the search for new drugs
Timo Jaeger et al.
BIOFACTORS (2006)
Mycobacterial manipulation of the host cell
ALK Hestvik et al.
FEMS MICROBIOLOGY REVIEWS (2005)
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity
P Brodin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach
M Manger et al.
CHEMBIOCHEM (2005)
Rab conversion as a mechanism of progression from early to late endosomes
J Rink et al.
CELL (2005)
Role of protein kinase G in growth and glutamine metabolism of Mycobacterium bovis BCG
L Nguyen et al.
JOURNAL OF BACTERIOLOGY (2005)
The Trojan horse: survival tactics of pathogenic mycobacteria in macrophages
L Nguyen et al.
TRENDS IN CELL BIOLOGY (2005)
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
SL Fink et al.
INFECTION AND IMMUNITY (2005)
Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
I Vergne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mycobacterium tuberculosis reprograms waves of phosphatidylinositol 3-phosphate on phagosomal organelles
J Chua et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nitric oxide generated from isoniazid activation by KatG:: Source of nitric oxide and activity against Mycobacterium tuberculosis
GS Timmins et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Prospects for clinical introduction of nitroimidazole antibiotics for the treatment of tuberculosis
CE Barry et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
Protein kinase G from pathogenic mycobacteria promotes survival within macrophages
A Walburger et al.
SCIENCE (2004)
The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo
S Cowley et al.
MOLECULAR MICROBIOLOGY (2004)
Kinome analysis of host response to mycobacterial infection: a novel technique in proteomics
ALK Hestvik et al.
INFECTION AND IMMUNITY (2003)
Mycobacterium tuberculosis phagosome maturation arrest:: Selective targeting of PI3P-dependent membrane trafficking
I Vergne et al.
TRAFFIC (2003)
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: Role of Rab7 and RILP
RE Harrison et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
RA Fratti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis
M Braunstein et al.
MOLECULAR MICROBIOLOGY (2003)
Role of glutathione in macrophage control of mycobacteria
V Venketaraman et al.
INFECTION AND IMMUNITY (2003)
4-alkoxy-2,6-diaminopyrimidine derivatives: Inhibitors of cyclin dependent kinases 1 and 2
V Mesguiche et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
Nitric oxide regulation of L-arginine uptake in murine and human macrophages
V Venketaraman et al.
TUBERCULOSIS (2003)
Molecular analysis of isoniazid resistance in Mycobacterium tuberculosis isolates recovered from South Korea
SY Kim et al.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2003)
Phagosome maturation: aging gracefully
OV Vieira et al.
BIOCHEMICAL JOURNAL (2002)
Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
JC Betts et al.
MOLECULAR MICROBIOLOGY (2002)
Iron-cofactored superoxide dismutase inhibits host responses to Mycobacterium tuberculosis
KM Edwards et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
I Jordens et al.
CURRENT BIOLOGY (2001)
Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest
RA Fratti et al.
JOURNAL OF CELL BIOLOGY (2001)
An essential role for phoP in Mycobacterium tuberculosis virulence
E Pérez et al.
MOLECULAR MICROBIOLOGY (2001)
Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy
T Bezabeh et al.
CELL DEATH AND DIFFERENTIATION (2001)
Induction of direct antimicrobial activity through mammalian toll-like receptors
S Thoma-Uszynski et al.
SCIENCE (2001)
Necrosis of lung epithelial cells during infection with Mycobacterium tuberculosis is preceded by cell permeation
KM Dobos et al.
INFECTION AND IMMUNITY (2000)
A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase
GL Newton et al.
BIOCHEMISTRY (2000)
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
CE Arris et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
CK Stover et al.
NATURE (2000)
分享论文
