4.5 Article

Inhibition of γH2AX, COX-2 and regulation of antioxidant enzymes in MPP+-exposed SH-SY5Y cells pre-treated with rutin

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Summary: The study demonstrates that rutin shows neuroprotective activity against MPP+-induced toxicity in SH-SY5Y cells, reducing changes in nuclear morphology, caspase activities, regulating cell signaling pathways, and affecting protein expression levels associated with autophagy.

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