期刊
MARINE DRUGS
卷 19, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/md19050246
关键词
marine sponge; bioactive compounds; microbial symbionts; antimicrobial activity; aquaculture; quorum quenching
资金
- Ministry of Higher Education Malaysia via the Higher Instituition Centre of Excellence (HICoE) [6369100]
- UCSI University Research Excellence & Innovation Grant [REIG-FAS-2020/032]
Marine sponges are valuable sources of bioactive compounds with antimicrobial and antiviral properties. These compounds can be used as antibacterial, antiviral, anti-malarial, and antifungal agents against human pathogens and fish pathogens. Their application as antimicrobial agents in veterinary commodities is also discussed.
Marine sponges are sessile invertebrates that can be found in temperate, polar and tropical regions. They are known to be major contributors of bioactive compounds, which are discovered in and extracted from the marine environment. The compounds extracted from these sponges are known to exhibit various bioactivities, such as antimicrobial, antitumor and general cytotoxicity. For example, various compounds isolated from Theonella swinhoei have showcased various bioactivities, such as those that are antibacterial, antiviral and antifungal. In this review, we discuss bioactive compounds that have been identified from marine sponges that showcase the ability to act as antibacterial, antiviral, anti-malarial and antifungal agents against human pathogens and fish pathogens in the aquaculture industry. Moreover, the application of such compounds as antimicrobial agents in other veterinary commodities, such as poultry, cattle farming and domesticated cats, is discussed, along with a brief discussion regarding the mode of action of these compounds on the targeted sites in various pathogens. The bioactivity of the compounds discussed in this review is focused mainly on compounds that have been identified between 2000 and 2020 and includes the novel compounds discovered from 2018 to 2021.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据