4.3 Article

Systemic lupus erythematosus and COVID-19 during pregnancy

期刊

LUPUS
卷 30, 期 7, 页码 1188-1191

出版社

SAGE PUBLICATIONS LTD
DOI: 10.1177/09612033211002270

关键词

Systemic lupus erythematosus; pregnancy; COVID-19

资金

  1. Dutch Arthritis Foundation (ReumaNederland) [LLP-26]

向作者/读者索取更多资源

The clinical characteristics of COVID-19 in pregnant patients with autoimmune disease like SLE are currently lacking. Two pregnant SLE patients with mild symptomatic COVID-19 infection had good outcomes without COVID-19 treatment, giving birth to healthy babies. One patient experienced a flare in SLE disease activity after discontinuing SLE treatment. Collaborative multidisciplinary care and individualized treatment decisions are important during unprecedented times like the current COVID-19 pandemic.
Background: The ongoing corona virus disease 2019 (COVID-19) pandemic is having a worldwide impact. Valuable information on the clinical characteristics of COVID-19 in pregnant patients with an autoimmune disease, such as systemic lupus erythematosus (SLE), is currently lacking. Methods: Herein, we describe the clinical presentation of 2 pregnant patients with SLE and mild symptomatic COVID-19 infection. Results: In both pregnant SLE patients, a watchful-waiting approach without initiation of treatment for COVID-19 was taken. No adverse outcomes were reported and both pregnancies resulted in healthy neonates born at term. In one patient we observed a flare in SLE disease activity, most likely attributed to discontinuing SLE treatment. Conclusion: Our report highlights the importance of multidisciplinary collaboration between health care professionals as well as individualized treatment decisions during unprecedented periods such as the current COVID-19 pandemic. Discontinuation of immunosuppressive drugs during the acute phase of a COVID-19 infection should be considered on a case-by-case basis. Maternal treatment decisions should be in line with current recommendations for treatment of rheumatic and musculoskeletal diseases during COVID-19 infection and in line with treatment of COVID- 19 during pregnancy.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.3
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据