4.4 Article

Direct oral anticoagulants in chronic thromboembolic pulmonary hypertension

期刊

JOURNAL OF THROMBOSIS AND THROMBOLYSIS
卷 52, 期 3, 页码 791-796

出版社

SPRINGER
DOI: 10.1007/s11239-021-02445-z

关键词

Chronic thromboembolic pulmonary hypertension; Oral anticoagulation; Vitamin K antagonists; Warfarin; Direct oral anticoagulants; Pulmonary embolism; Venous thromboembolism

向作者/读者索取更多资源

Patients with chronic thromboembolic pulmonary hypertension (CTEPH) are recommended indefinite anticoagulation therapy, with a recent shift towards direct oral anticoagulants (DOACs) despite lacking safety and efficacy data in this population. Important issues and controversies surrounding the use of DOACs in CTEPH patients need further clinical research exploration.
Chronic thromboembolic pulmonary hypertension (CTEPH) represents the later stage consequence of at least one or more unresolved episodes of acute pulmonary embolism; thus, indefinite anticoagulation is strongly recommended by current practice guidelines. Historically, vitamin K antagonists have been widely used in these patients. However, recent data indicate a shift toward direct oral anticoagulants (DOACs), despite lack of data on the safety and efficacy in this patient population. Herein, we briefly discuss the current rationale for oral anticoagulation use in CTEPH, addressing important issues and controversies involved with the use of DOACs, opening a strategy for further clinical research in the field of oral anticoagulation.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据