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注意:仅列出部分参考文献,下载原文获取全部文献信息。Insights into ADAMTS13 structure: impact on thrombotic thrombocytopenic purpura diagnosis and management
Elien Roose et al.
CURRENT OPINION IN HEMATOLOGY (2020)
Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function
An-Sofie Schelpe et al.
BLOOD ADVANCES (2020)
Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation
Joshua Muia et al.
BLOOD (2019)
Exploring the minimal structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering
Jian Zhu et al.
BLOOD (2019)
Identification of cysteine thiol-based linkages in ADAMTS13 in support of a non-proteolytic regulation of von Willebrand factor
Hanspeter Rottensteiner et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2019)
Crystal structure and substrate-induced activation of ADAMTS13
Anastasis Petri et al.
NATURE COMMUNICATIONS (2019)
AFM Imaging Reveals Multiple Conformational States of ADAMTS13
Shanshan Yu et al.
JOURNAL OF BIOLOGICAL ENGINEERING (2019)
von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain
Changjie Zhang et al.
BLOOD ADVANCES (2019)
An open conformation of ADAMTS-13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura
E. Roose et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2018)
Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Elien Roose et al.
THROMBOSIS AND HAEMOSTASIS (2018)
Conformational quiescence of ADAMTS-13 prevents proteolytic promiscuity
K. South et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2016)
ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model
Eric M. Ostertag et al.
TRANSFUSION (2016)
ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 1. Structural and functional characterization in vitro
Eric M. Ostertag et al.
TRANSFUSION (2016)
High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome
Veronica C. Casina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Allosteric activation of ADAMTS13 by von Willebrand factor
Joshua Muia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Conformational activation of ADAMTS13
Kieron South et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Essential Domains of A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13 Metalloprotease Required for Modulation of Arterial Thrombosis
Juan Xiao et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain
Wouter Pos et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF
Wouter Pos et al.
BLOOD (2010)
Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
X. Long Zheng et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)
Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site
Thomas J. Raife et al.
BLOOD (2009)
A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF
Sara Zanardelli et al.
BLOOD (2009)
Pathogenesis of thrombotic microangiopathies
X. Long Zheng et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
Mechanistic studies on ADAMTS13 catalysis
Enrico Di Stasio et al.
BIOPHYSICAL JOURNAL (2008)
Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity
Weiqiang Gao et al.
BLOOD (2008)
Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13
Wenjing Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
Ping Zhang et al.
BLOOD (2007)
Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease
Weiqiang Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor
JH Ai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cleavage of ultralarge multimers of von Willebrand factor by C-terminal-truncated mutants of ADAMTS-13 under flow
ZY Tao et al.
BLOOD (2005)
Binding of ADAMTS13 to von Willebrand factor
EM Majerus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay
K Kokame et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura
XL Zheng et al.
BLOOD (2004)
Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
XL Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13)
B Plaimauer et al.
BLOOD (2002)
Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
XL Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
GG Levy et al.
NATURE (2001)