Incidence of psoriasis among adults in the United States: A sex- and age-adjusted population analysis

Background: Information on recent trends in overall and subgroup incidences in psoriasis is limited. Objective: To estimate current incidence of psoriasis in the United States, compare incidences among demographic subgroups, and evaluate recent disease trends. Methods: Retrospective cohort analysis of psoriasis patients identified with electronic health records between 2014 and 2018. Results: Incidence rate in the overall population (n = 2,152,192) was 63.8 (95% confidence interval [CI] 61.8-65.8) per 100,000 person-years. Incidence increased with age and peaked among individuals aged 70 to 79 years (92.3 [95% CI 85.1-100.0] per 100,000 person-years). Incidence was similar between men (62.8 [95% CI 59.8-65.9] per 100,000 person-years) and women (64.8 [95% CI 62.2-67.4] per 100,000 person-years). Standardized incidence rate for Whites (75.3 [95% CI 72.7-78.0] per 100,000 person-years) was greater than that for Hispanic/Latino patients (52.2 [95% CI 44.9-60.3] per 100,000 person-years; P < .001), patients of other race (54.3 [95% CI 46.5-62.9] per 100,000 person-years; P < .001), and Blacks (24.9 [95% CI 21.4-28.8] per 100,000 person-years; P < .001). Incidence appears to be stable within a recent 5-year period. Limitations: Estimates were derived from approximately 15% of the health care-seeking US population. Conclusion: Psoriasis incidence in the United States appears to increase with age, is similar between sexes, and is greatest among Whites.

Automated summary

Psoriasis incidence in the United States increases with age, is similar between sexes, and is highest among Whites. The incidence rate appears to be stable within the recent 5-year period.