4.5 Article

Selective degradation of the estrogen receptor in the treatment of cancers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Synergistic Cytotoxic and Apoptotic Effects of Local Probiotic Lactobacillus Brevis Isolated from Regional Dairy Products in Combination with Tamoxifen

Zahra Nasiri et al.

Summary: The study suggests that supernatant of Local Probiotic Lactobacillus Brevis can induce apoptosis in breast cancer cells and enhance the inhibitory effect of Tamoxifen, potentially serving as an adjuvant therapy in cancer treatment and prevention.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021)

Editorial Material Cell Biology

Targeting selective autophagy by AUTAC degraders

Daiki Takahashi et al.

AUTOPHAGY (2020)

Article Chemistry, Medicinal

Development of cell-permeable peptide-based PROTACs targeting estrogen receptor α

Yuxuan Dai et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Multidisciplinary Sciences

PHOTACs enable optical control of protein degradation

Martin Reynders et al.

SCIENCE ADVANCES (2020)

Review Chemistry, Medicinal

Targeting estrogen receptor α for degradation with PROTACs: A promising approach to overcome endocrine resistance

Xin Lin et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Computer-Aided Ligand Discovery for Estrogen Receptor Alpha

Divya Bafna et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer

Annamaria Salvati et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

Richard T. Timms et al.

SCIENCE (2019)

Article Chemistry, Medicinal

PROTAC-Mediated Degradation of Estrogen Receptor in the Treatment of Cancer

Robert B. Kargbo

ACS Medicinal Chemistry Letters (2019)

Article Biochemistry & Molecular Biology

A modular PROTAC design for target destruction using a degradation signal based on a single amino acid

Karthigayan Shanmugasundaram et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

The PROTAC technology in drug development

Yutian Zou et al.

CELL BIOCHEMISTRY AND FUNCTION (2019)

Review Oncology

Molecular mechanisms of resistance to CDK4/6 inhibitors in breast cancer: A review

Kamal Pandey et al.

INTERNATIONAL JOURNAL OF CANCER (2019)

Review Endocrinology & Metabolism

Estrogen Signaling in ERα-Negative Breast Cancer: ERβ and GPER

Rainer Girgert et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Biochemistry & Molecular Biology

Bivalent Ligands for Protein Degradation in Drug Discovery

Marcel Scheepstra et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)

Meeting Abstract Oncology

ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer

J. J. Flanagan et al.

CANCER RESEARCH (2019)

Review Biochemistry & Molecular Biology

PROTACs: great opportunities for academia and industry

Xiuyun Sun et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)

Review Endocrinology & Metabolism

Next-Generation ERα Inhibitors for Endocrine-Resistant ER+ Breast Cancer

Sean W. Fanning et al.

ENDOCRINOLOGY (2019)

Article Pharmacology & Pharmacy

Duality of estrogen receptor β action in cancer progression

T. C. Guillette et al.

CURRENT OPINION IN PHARMACOLOGY (2018)

Article Pharmacology & Pharmacy

Synthesis and biological evaluation of novel cyclopropyl derivatives as subtype-selective ligands for estrogen receptor

Zunyuan Wang et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2018)

Article Chemistry, Medicinal

New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons

Lucia Wang et al.

ACS MEDICINAL CHEMISTRY LETTERS (2018)

Article Biochemistry & Molecular Biology

Homo-PROTACs for the Chemical Knockdown of Cereblon

Christian Steinebach et al.

ACS CHEMICAL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Development of Stabilized Peptide-Based PROTACs against Estrogen Receptor alpha

Yanhong Jiang et al.

ACS CHEMICAL BIOLOGY (2018)

Review Biotechnology & Applied Microbiology

Cornerstones of CRISPR-Cas in drug discovery and therapy

Christof Fellmann et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Oncology

Fulvestrant in advanced breast cancer: evidence to date and place in therapy

Katalin Boer

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2017)

Article Biochemistry & Molecular Biology

Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy

Philipp Ottis et al.

ACS CHEMICAL BIOLOGY (2017)

Article Chemistry, Multidisciplinary

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras

Honorine Lebraud et al.

ACS CENTRAL SCIENCE (2016)

Article Chemistry, Multidisciplinary

Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging

Jeffrey L. Gustafson et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Endocrinology & Metabolism

Estrogen receptor alpha and beta in health and disease

Min Jia et al.

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2015)

Review Genetics & Heredity

Knocking down disease: a progress report on siRNA therapeutics

Anders Wittrup et al.

NATURE REVIEWS GENETICS (2015)

Article Chemistry, Medicinal

Design and synthesis of tamoxifen derivatives as a selective estrogen receptor down-regulator

Takuji Shoda et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Chemistry, Medicinal

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Yosuke Demizu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Biochemistry & Molecular Biology

Design, synthesis and biological evaluation of nuclear receptor-degradation inducers

Yukihiro Itoh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Impact of linker length on the activity of PROTACs

Kedra Cyrus et al.

MOLECULAR BIOSYSTEMS (2011)

Article Biochemistry & Molecular Biology

Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins

Taavi K. Neklesa et al.

NATURE CHEMICAL BIOLOGY (2011)

Review Oncology

The different roles of ER subtypes in cancer biology and therapy

Christoforos Thomas et al.

NATURE REVIEWS CANCER (2011)

Article Biochemistry & Molecular Biology

Two-Headed PROTAC: An Effective New Tool for Targeted Protein Degradation

Kedra Cyrus et al.

CHEMBIOCHEM (2010)

Article Cell Biology

Unliganded estrogen receptor-β regulation of genes is inhibited by tamoxifen

Nitzan Levy et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Article Biology

Mechanisms of estrogen receptor-α upregulation in breast cancers

Yasuo Miyoshi et al.

MEDICAL MOLECULAR MORPHOLOGY (2010)

Article Chemistry, Medicinal

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

Ashley R. Schneekloth et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Biochemistry & Molecular Biology

Coregulators in nuclear estrogen receptor action - From concept to therapeutic targeting

JM Hall et al.

MOLECULAR INTERVENTIONS (2005)

Article Chemistry, Medicinal

Use of PROTACS as molecular probes of angiogenesis

P Bargagna-Mohan et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Chemistry, Multidisciplinary

Chemical genetic control of protein levels: Selective in vivo targeted degradation

JS Schneekloth et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Oncology

Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action

CK Osborne et al.

BRITISH JOURNAL OF CANCER (2004)

Article Chemistry, Medicinal

Degradation of target protein in living cells by small-molecule proteolysis inducer

D Zhang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)

Article Biochemical Research Methods

Development of protacs to target cancer-promoting proteins for ubiquitination and degradation

KM Sakamoto et al.

MOLECULAR & CELLULAR PROTEOMICS (2003)

Review Physiology

Mechanisms of estrogen action

S Nilsson et al.

PHYSIOLOGICAL REVIEWS (2001)

Article Multidisciplinary Sciences

Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

KM Sakamoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)