期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 86, 期 7, 页码 5423-5430出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.1c00273
关键词
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资金
- National Research Foundation of Korea (NRF) - Korea government (MSIT) [2017R1A2B2003614]
- National Research Foundation of Korea [2017R1A2B2003614] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The Pd-catalyzed/Cu-mediated oxidative dehydrosulfurative carbon-oxygen cross-coupling reaction offers a facile access to biologically and pharmacologically valuable 2-aryloxypyrimidine derivatives due to the ready availability of diverse DHPMs and aryl alcohols.
A Pd-catalyzed/Cu-mediated oxidative dehydrosulfurative carbon-oxygen cross-coupling reaction of 3,4-dihydropyrimidin-1H-2-thiones (DHPMs) with aryl alcohols is described. Due to the ready availability of diverse DHPMs and aryl alcohols, the reaction method offers facile access to biologically and pharmacologically valuable 2-aryloxypyrimidine derivatives with rapid diversification.
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