4.7 Review

The NLRP3 inflammasome: an emerging therapeutic target for chronic pain

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Summary: Morphine and fentanyl have differential effects on the activation of NLRP3 inflammasome in glial and neuronal cells in the dorsal raphe nucleus (DRN), suggesting the involvement of neuroinflammation in opioid-induced analgesia and fentanyl-induced hyperalgesia.

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