相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Ferulic Acid Ameliorates MPP+/MPTP-Induced Oxidative Stress via ERK1/2-Dependent Nrf2 Activation: Translational Implications for Parkinson Disease Treatment
Xu Li et al.
MOLECULAR NEUROBIOLOGY (2020)
Perillyl Alcohol Mitigates Behavioural Changes and Limits Cell Death and Mitochondrial Changes in Unilateral 6-OHDA Lesion Model of Parkinson's Disease Through Alleviation of Oxidative Stress
Ehraz Anis et al.
NEUROTOXICITY RESEARCH (2020)
Puerarin suppresses MPP+/MPTP-induced oxidative stress through an Nrf2-dependent mechanism
Xiaoming Li et al.
FOOD AND CHEMICAL TOXICOLOGY (2020)
p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle
Mami Yamada et al.
FASEB JOURNAL (2019)
Iron-related nigral degeneration influences functional topology mediated by striatal dysfunction in Parkinson's disease
Xiaojun Guan et al.
NEUROBIOLOGY OF AGING (2019)
Benefits of Vitamins in the Treatment of Parkinson's Disease
Xiuzhen Zhao et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Possible involvement of transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effect of caffeic acid on paraquat-induced oxidative damage in Drosophila melanogaster
Ricardo Gomes dos Santos Nunes et al.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2019)
Arsenic trioxide suppresses acute graft-versus-host disease by activating the Nrf2/HO-1 pathway in mice
Xiaoli Hu et al.
BRITISH JOURNAL OF HAEMATOLOGY (2019)
Grape Peel Extract and Resveratrol Inhibit Wrinkle Formation in Mice Model Through Activation of Nrf2/HO-1 Signaling Pathway
Jungeun Kim et al.
JOURNAL OF FOOD SCIENCE (2019)
Neuroprotective Role of the Nrf2 Pathway in Subarachnoid Haemorrhage and Its Therapeutic Potential
Ardalan Zolnourian et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
miR-144 regulates oxidative stress tolerance of thalassemic erythroid cell via targeting NRF2
Kanitta Srinoun et al.
ANNALS OF HEMATOLOGY (2019)
S-1-propenylmercaptocysteine protects murine hepatocytes against oxidative stress via persulfidation of Keap1 and activation of Nrf2
Restituto Tocmo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway
Weitang Liao et al.
FREE RADICAL RESEARCH (2019)
PERK regulates Nrf2/ARE antioxidant pathway against dibutyl phthalate-induced mitochondrial damage and apoptosis dependent of reactive oxygen species in mouse spermatocyte-derived cells
Guowei Zhang et al.
TOXICOLOGY LETTERS (2019)
Long Term Response to Levodopa in Parkinson's Disease
Harsh Gupta et al.
JOURNAL OF PARKINSONS DISEASE (2019)
Oxidative stress and α-synuclein conspire in vulnerable neurons to promote Parkinson's disease progression
Kelvin C. Luk
JOURNAL OF CLINICAL INVESTIGATION (2019)
The Therapeutic Implications of Tea Polyphenols against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD)
Zhi Dong Zhou et al.
CELLS (2019)
Neuroprotective effects of protocatechuic aldehyde through PLK2 / p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease
Chao Guo et al.
AGING-US (2019)
Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury
Kui-Chao Qu et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019)
Astragaloside IV ameliorates motor deficits and dopaminergic neuron degeneration via inhibiting neuroinflammation and oxidative stress in a Parkinson's disease mouse model
Cong Yang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated antioxidant defense activation
Jing Ge et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2019)
5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress
Li-Li Xu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Redox regulation by NRF2 in aging and disease
Cody J. Schmidlin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons
Guo-Qing Wang et al.
PHARMACOLOGICAL RESEARCH (2019)
The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases
Wenjun Tu et al.
AGING AND DISEASE (2019)
Neuroprotective effect of fermented papaya preparation by activation of Nrf2 pathway in astrocytes
Shinki Murakami et al.
NUTRITIONAL NEUROSCIENCE (2018)
Nrf2: Molecular and epigenetic regulation during aging
A. Silva-Palacios et al.
AGEING RESEARCH REVIEWS (2018)
Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A
Marta Pajares et al.
AUTOPHAGY (2018)
Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages
Stefanie Dichtl et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Mkp-1 protects mice against toxin-induced liver damage by promoting the Nrf2 cytoprotective response
Lin Luo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Rosmarinic acid attenuates β-amyloid-induced oxidative stress via Akt/GSK-3β/Fyn-mediated Nrf2 activation in PC12 cells
Hua Rong et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Targeting crosstalk between Nuclear factor (erythroid-derived 2)-like 2 and Nuclear factor kappa beta pathway by Nrf2 activator dimethyl fumarate in epileptogenesis
Neha Singh et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2018)
Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease
Fabiana Morroni et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
Suppression of microRNA-144-3p attenuates oxygen-glucose deprivation/reoxygenation-induced neuronal injury by promoting Brg1/Nrf2/ARE signaling
Yanru Li et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2018)
Beneficial Effects of Flavonoids Against Parkinson's Disease
Un Ju Jung et al.
JOURNAL OF MEDICINAL FOOD (2018)
Grape seed procyanidin extract ameliorates lead-induced liver injury via miRNA153 and AKT/GSK-3 beta/Fyn-mediated Nrf2 activation
Biying Liu et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2018)
UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F
Weihua Zhou et al.
MOLECULAR CELL (2018)
Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo
Ryan S. Wible et al.
MOLECULAR PHARMACOLOGY (2018)
The epidemiology of Parkinson's disease in the Italian region Friuli Venezia Giulia: a population-based study with administrative data
Francesca Valent et al.
NEUROLOGICAL SCIENCES (2018)
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
Antonio Cuadrado et al.
PHARMACOLOGICAL REVIEWS (2018)
Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2
Lijin Wang et al.
TOXICOLOGY LETTERS (2018)
Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson's Disease
Li Zhang et al.
AGING AND DISEASE (2018)
Lycopene Triggers Nrf2-AMPK Cross Talk to Alleviate Atrazine-Induced Nephrotoxicity in Mice
Jia Lin et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
Beneficial effects of Oltipraz, nuclear factor - erythroid-2-related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model
Emre Can Polat et al.
INTERNATIONAL BRAZ J UROL (2018)
Tetramethylpyrazine Ameliorates Rotenone-Induced Parkinson's Disease in Rats: Involvement of Its Anti-Inflammatory and Anti-Apoptotic Actions
Haidy E. Michel et al.
MOLECULAR NEUROBIOLOGY (2017)
Nrf2 mitigates LRRK2-and α-synuclein-induced neurodegeneration by modulating proteostasis
Gaia Skibinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Environmental exposure to pesticides and the risk of Parkinson's disease in the Netherlands
Maartje Brouwer et al.
ENVIRONMENT INTERNATIONAL (2017)
Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1
Weixia Sun et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
被撤回的出版物: Diallyl trisulfide, a garlic polysulfide protects against As-induced renal oxidative nephrotoxicity, apoptosis and inflammation in rats by activating the Nrf2/ARE signaling pathway (Retracted article. See vol. 85, 2020)
S. Miltonprabu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2017)
miR-432 Induces NRF2 Stabilization by Directly Targeting KEAP1
Burak Akdemir et al.
MOLECULAR CANCER RESEARCH (2017)
Central administration of tert-butylhydroquinone attenuates hypertension via regulating Nrf2 signaling in the hypothalamic paraventricular nucleus of hypertensive rats
Juan Bai et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)
Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1)
Alberto Bresciani et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)
The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2
Michela Campolo et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Therapeutic Potential of the Activators of the Nuclear Factor Erythroid 2-Related Factor 2-Antioxidant Response Element Pathway in Brain Disorders
Toshiaki Kume
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2017)
Ellagic acid exerts protective effect in intrastriatal 6-hydroxydopamine rat model of Parkinson's disease: Possible involvement of ERβ/Nrf2/HO-1 signaling
Tourandokht Baluchnejadmojarad et al.
BRAIN RESEARCH (2017)
Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway
Qunli Cui et al.
MOLECULAR MEDICINE REPORTS (2016)
Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease
Isabel Lastres-Becker et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes
Marta Pajares et al.
AUTOPHAGY (2016)
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease
Hanaa Hibishy Gaballah et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Antidepressant effects of TBE-31 and MCE-1, the novel Nrf2 activators, in an inflammation model of depression
Wei Yao et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease
Manuj Ahuja et al.
JOURNAL OF NEUROSCIENCE (2016)
Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
Eri H. Kobayashi et al.
NATURE COMMUNICATIONS (2016)
An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders
Yang Yang et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2015)
Phytoestrogen β-Ecdysterone Protects PC12 Cells Against MPP+-Induced Neurotoxicity In Vitro: Involvement of PI3K-Nrf2-Regulated Pathway
Yu Zou et al.
TOXICOLOGICAL SCIENCES (2015)
Oxidative stress: a concept in redox biology and medicine
Helmut Sies
REDOX BIOLOGY (2015)
NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions
Hitoshi Murata et al.
PLOS ONE (2015)
Fatty Acid Composition of the Anterior Cingulate Cortex Indicates a High Susceptibility to Lipid Peroxidation in Parkinson's Disease
Sarah K. Abbott et al.
JOURNAL OF PARKINSONS DISEASE (2015)
Genetic associations of Nrf2-encoding NFE2L2 variants with Parkinson s disease a multicenter study
Malin von Otter et al.
BMC MEDICAL GENETICS (2014)
The Impact of miRNA-Based Molecular Diagnostics and Treatment of NRF2-Stabilized Tumors
Shinsuke Yamamoto et al.
MOLECULAR CANCER RESEARCH (2014)
Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson's disease: Involvement of ERK1/2-Nrf2 signaling pathway
Xiao-Li Wang et al.
LIFE SCIENCES (2014)
Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway
Juan Wu et al.
TOXICOLOGY (2014)
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
John D. Hayes et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - Implication in modification of radiation damage
Anuranjani et al.
REDOX BIOLOGY (2014)
Role of Nrf2 in Oxidative Stress and Toxicity
Qiang Ma
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)
Regulation of Lifespan by the Mitochondrial Electron Transport Chain: Reactive Oxygen Species-Dependent and Reactive Oxygen Species-Independent Mechanisms
Filippo Scialo et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease
Navneet Ammal Kaidery et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Roles of Keap1-Nrf2 System in Upper Aerodigestive Tract Carcinogenesis
Akira Ohkoshi et al.
CANCER PREVENTION RESEARCH (2013)
RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
Hongyan Wang et al.
CANCER RESEARCH (2013)
Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1
Jinbum Bae et al.
MOLECULES AND CELLS (2013)
Akt/Nrf2 Activated Upregulation of Heme Oxygenase-1 Involves in the Role of Rg1 Against Ferrous Iron-Induced Neurotoxicity in SK-N-SH Cells
Xixun Du et al.
NEUROTOXICITY RESEARCH (2013)
The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains
J-H Kim et al.
ONCOGENE (2013)
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
Liam Baird et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Carnosic Acid Prevents 6-Hydroxydopamine-Induced Cell Death in SH-SY5Y Cells via Mediation of Glutathione Synthesis
Jing-Hsien Chen et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
Baicalein Protects against 6-OHDA-Induced Neurotoxicity through Activation of Keap1/Nrf2/HO-1 and Involving PKCα and PI3K/AKT Signaling Pathways
Zaijun Zhang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)
Astrocyte-Specific Overexpression of Nrf2 Delays Motor Pathology and Synuclein Aggregation throughout the CNS in the Alpha-Synuclein Mutant (A53T) Mouse Model
Li Gan et al.
JOURNAL OF NEUROSCIENCE (2012)
NADPH Oxidase 1 Mediates α-Synucleinopathy in Parkinson's Disease
Ana Clara Cristovao et al.
JOURNAL OF NEUROSCIENCE (2012)
Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis
Patricia Rada et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
Yoichi Imaizumi et al.
MOLECULAR BRAIN (2012)
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease
Maria Cecilia Barone et al.
DISEASE MODELS & MECHANISMS (2011)
SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
Patricia Rada et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Evaluation of Markers of Oxidative Stress, Antioxidant Function and Astrocytic Proliferation in the Striatum and Frontal Cortex of Parkinson's Disease Brains
Rajeswara Babu Mythri et al.
NEUROCHEMICAL RESEARCH (2011)
Identification of organoselenium compounds that possess chemopreventive properties in human prostate cancer LNCaP cells
Riyako Terazawa et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease
Malin von Otter et al.
BMC MEDICAL GENETICS (2010)
Determination of reactive oxygen species associated with the degeneration of dopaminergic neurons during dopamine metabolism
Mayumi Yamato et al.
FREE RADICAL RESEARCH (2010)
Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1
Keiko Taguchi et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
Toshihiko Ogura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription
Lichuan Yang et al.
PLOS ONE (2009)
Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response
Zheng Sun et al.
PLOS ONE (2009)
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
Pei-Chun Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
(-)-epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells
Hye-Kyung Na et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3
Girish Rachakonda et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes
Jianyong Zhang et al.
BIOCHEMICAL JOURNAL (2007)
Expression of Nrf2 in neurodegenerative diseases
Chenere P. Ramsey et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
Casey M. Clements et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism
Kit I. Tong et al.
BIOLOGICAL CHEMISTRY (2006)
Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins
K Nakaso et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells
S Papaiahgari et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
P Nioi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
AT Dinkova-Kostova et al.
BIOCHEMISTRY (2005)
Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity - induced by 1-methyl-4-(2 '-methylphenyl)-1,2,3,6-tetrahydropyridine (2 '-methyl-MPTP) in mice
MH Abdel-Wahab
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2005)
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
AT Dinkova-Kostova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism
YM Chen et al.
JOURNAL OF NEUROCHEMISTRY (2001)
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
A Enomoto et al.
TOXICOLOGICAL SCIENCES (2001)
分享论文
