相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands
Jing-Fang Yang et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Synthesis of 4,4-Dimethyl-1,6-heptadiyne and Alcyopterosin O
Amir Tavakoli et al.
ORGANIC LETTERS (2020)
Crystal Structure of the Human Cannabinoid Receptor CB2
Xiaoting Li et al.
CELL (2019)
Reaction Discovery Using Neopentylene-Tethered Coupling Partners: Cycloisomerization/Oxidation of Electron-Deficient Dienynes
Nicholas J. Kramer et al.
ORGANIC LETTERS (2017)
Synthetic Pot: Not Your Grandfather's Marijuana
Benjamin M. Ford et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Synthesis and Pharmacological Profiling of the Metabolites of Synthetic Cannabinoid Drugs APICA, STS-135, ADB-PINACA, and 5F-ADB-PINACA
Mitchell Longworth et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Crystal Structure of the Human Cannabinoid Receptor CB1
Tian Hua et al.
CELL (2016)
Hexafluoro-2-propanol-Promoted Intermolecular Friedel-Crafts Acylation Reaction
Rakesh H. Vekariya et al.
ORGANIC LETTERS (2016)
Endocannabinoid signaling at the periphery: 50 years after THC
Mauro Maccarrone et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Psychoactive substances-Some new, some old: A scan of the situation in the U.S.
Jane Carlisle Maxwell
DRUG AND ALCOHOL DEPENDENCE (2014)
Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids
Jenny L. Wiley et al.
LIFE SCIENCES (2014)
The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse
Samuel D. Banister et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Effects of Schedule I drug laws on neuroscience research and treatment innovation
David J. Nutt et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Cannabinoids in disguise: Δ9-Tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles
Jenny L. Wiley et al.
NEUROPHARMACOLOGY (2013)
Synthesis of High-Value 1,6-Enynes by Tandem Fragmentation/Olefination
Tung T. Hoang et al.
ORGANIC LETTERS (2013)
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
Lisa K. Brents et al.
BIOCHEMICAL PHARMACOLOGY (2012)
MMPBSA.py: An Efficient Program for End-State Free Energy Calculations
Bill R. Miller et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Design, Synthesis, and Pharmacological Characterization of Indol-3-ylacetamides, Indol-3-yloxoacetamides, and Indol-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists
Serena Pasquini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities
Roger G. Pertwee
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
Towards the use of cannabinoids as antitumour agents
Guillermo Velasco et al.
NATURE REVIEWS CANCER (2012)
Update on the endocannabinoid system as an anticancer target
Anna Maria Malfitano et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity
Lisa K. Brents et al.
PLOS ONE (2011)
Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown
Patricia H. Reggio
CURRENT MEDICINAL CHEMISTRY (2010)
Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
David P. Finn
IMMUNOBIOLOGY (2010)
Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database
Paul C. D. Hawkins et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Software News and Update AutoDock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization, and Multithreading
Oleg Trott et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure-Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor Ligands
Serena Pasquini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Indol-3-ylcycloalkyl Ketones: Effects of N1 Substituted Indole Side Chain Variations on CB2 Cannabinoid Receptor Activity
Jennifer M. Frost et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Cannabinoid receptor ligands as potential anticancer agents - high hopes for new therapies?
Susanne Oesch et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2009)
CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury
Ming Zhang et al.
MICROVASCULAR RESEARCH (2009)
Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis
Vanessa Deveaux et al.
PLOS ONE (2009)
Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain
J. Guindon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models
B. B. Yao et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Cannabinoid receptors and the regulation of bone mass
I. Bab et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Cannabinoid CB2 receptors in human brain inflammation
C. Benito et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
741 4-Oxo-1,4-Dihydroquinoline-3-Carboxamides Derivatives As New Potent and Selective Cb2 Agonists with Anti-Inflammatory and Analgesic Properties in the Gut
Mathilde Body-Malapel et al.
GASTROENTEROLOGY (2008)
Indol-3-yl-tetramethylcyclopropyl ketones:: Effects of indole ring substitution on CB2 cannabinoid receptor activity
Jennifer M. Frost et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Indoles and related compounds as cannabinoid ligands
Clementina Manera et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Targeting the endocannabinoid system: to enhance or reduce?
Vincenzo Di Marzo
NATURE REVIEWS DRUG DISCOVERY (2008)
Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures - A short review
Ivana Svizenska et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)
Cannabinoids and neuroprotection in basal ganglia disorders
Onintza Sagredo et al.
MOLECULAR NEUROBIOLOGY (2007)
Targeting cannabinoid agonists for inflammatory and neuropathic pain
Yuan Cheng et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Attenuation of allergic contact dermatitis through the endocannabinoid system
Meliha Karsak et al.
SCIENCE (2007)
Dialkyl and methyl-alkyl zirconocenes: Synthesis and characterization of zirconocene-alkyls that model the polymeryl chain in alkene polymerizations
Sara B. Klamo et al.
ORGANOMETALLICS (2007)
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
Jennifer L. Shoemaker et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Cannabinoid CB2 receptor: a new target for controlling neural cell survival?
Javier Fernandez-Ruiz et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists
G. T. Whiteside et al.
CURRENT MEDICINAL CHEMISTRY (2007)
A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo
CA Lunn et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
The endocannabinoid system as an emerging target of pharmacotherapy
Pal Pacher et al.
PHARMACOLOGICAL REVIEWS (2006)
Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor
JR Savinainen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
Structure-activity relationships for 1-alkyl-3-(l-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors:: steric and electronic effects of naphthoyl substituents.: New highly selective CB2 receptor agonists
JW Huffman et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
The central cannabinoid receptor inactivation suppresses endocrine reproductive functions
T Wenger et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)