4.6 Article

Poly(L-lactic acid) monofilaments for biodegradable braided self-expanding stent

期刊

JOURNAL OF MATERIALS SCIENCE
卷 56, 期 21, 页码 12383-12393

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SPRINGER
DOI: 10.1007/s10853-021-06021-x

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资金

  1. Major State Basic Research Development Program of China [2018YFA0704102]
  2. National Natural Science Foundation of China [51775107, 51905276]
  3. Nanjing Special Fund Project for Health Scientific and Technological Development [YKK18269]

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This study investigates the use of PLLA monofilaments for braided carotid stents, characterizing the properties of the monofilaments and demonstrating that the braided PLLA stents have good mechanical properties and can provide adequate support.
Although poly(l-lactic acid) (PLLA) is the widely used material for bioresorbable stents, publications on PLLA braided stents are still lacking. In this paper, the PLLA monofilaments were prepared via melt spinning and solid-state drawing. The total draw ratios are from 2.8 to 30.8. The properties of the monofilaments, such as crystallinity, elastic modulus, elongation at break, were characterized. Due to the relatively good mechanical properties, PLLA monofilaments with draw ratio of 16.8 were used to braid carotid stents. The curve of the radial force of the braided PLLA stent almost overlaps with that of a Carotid Wallstent with similar parameters, which indicates that the braided PLLA stent can provide adequate support to the carotid lesion.

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