期刊
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
卷 96, 期 -, 页码 284-293出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jiec.2021.01.034
关键词
Zwitterion; Carboxybetaine; Copolymer; Antifouling; Biofouling; Biocompatibility
资金
- Korea University Ansan Hospital grant [K1810971]
Zwitterionic copolymers, specifically those containing carboxybetaine derivatives, have been optimized for enhanced antifouling properties and biocompatibility. The copolymerization of carboxybetaine with hydrophobic monomers, such as trimethylsiloxy, shows promising results in creating a versatile antifouling surface using a simple and practical method. This study highlights the importance of elaborate copolymerization for achieving optimal functionality without compromising individual monomer properties.
Zwitterionic polymers including carboxybetaine derivatives are widely utilized as biocompatible antifouling materials in the way of copolymerization for the enhanced functionality. The aim of this study was to optimize the structure of copolymer in order to present a versatile antifouling property against both polar and nonpolar foulants as well as biocompatibility. Copolymers of zwitterionic carboxybetaine and several hydrophobic monomers were synthesized and coated on the glass substrate by a simple dipcoating method. The antifouling performance against polar and nonpolar foulants, adhesion property of cells and platelets on the coated surfaces were investigated. The optimal copolymer-coated surface with low fouling and fewer thrombotic events was shown to be a carboxybetaine copolymer in combination with the trimethylsiloxy group. This result suggests that elaborate copolymerization makes it possible to create a versatile antifouling surface using a simple and practical method without compromising the functionality of each monomer. (C) 2021 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据