4.7 Article

Deciphering of antibiotic resistance genes (ARGs) and potential abiotic indicators for the emergence of ARGs in an interconnected lake-river-reservoir system

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Occurrence of antibiotics and antibiotic resistance genes in the Fuxian Lake and antibiotic source analysis based on principal component analysis-multiple linear regression model

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Summary: The study investigated the source contribution and correlations between antibiotics and ARGs in surface water of Fuxian Lake. Results showed that SMX and OFL were the dominant antibiotics and their corresponding ARGs posed medium risk to aquatic organisms, mainly originating from anthropogenic sources. The presence of ARGs in the lake was significantly lower than in inflowing rivers, suggesting inconsistent correlations between antibiotics and ARGs in the lake.

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