4.8 Article

Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation

Wenyu Zhang et al.

CELL DEATH AND DIFFERENTIATION (2020)

Article Medicine, Research & Experimental

Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

Nikita S. Sharma et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

Daqian Xu et al.

NATURE (2020)

Article Oncology

PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis

Lin Tuo et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Review Biochemistry & Molecular Biology

Gluconeogenesis in cancer cells - Repurposing of a starvation-induced metabolic pathway?

Gabriele Grasmann et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

Review Gastroenterology & Hepatology

Metabolic rearrangements in primary liver cancers: cause and consequences

Letizia Satriano et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Review Oncology

State-of-the-art strategies for targeting the DNA damage response in cancer

Patrick G. Pilie et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Review Biophysics

O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle

John A. Hanover et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2018)

Article Multidisciplinary Sciences

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Roselle Gelinas et al.

NATURE COMMUNICATIONS (2018)

Review Endocrinology & Metabolism

O-GlcNAc: A Sweetheart of the Cell Cycle and DNA Damage Response

Caifei Liu et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Article Biochemistry & Molecular Biology

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Darya Zibrova et al.

BIOCHEMICAL JOURNAL (2017)

Article Biochemistry & Molecular Biology

Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation

Changmin Peng et al.

MOLECULAR CELL (2017)

Review Cell Biology

Protein O-GlcNAcylation: emerging mechanisms and functions

Xiaoyong Yang et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Gastroenterology & Hepatology

Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma

Zeribe Chike Nwosu et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2017)

Review Biochemistry & Molecular Biology

O-GIcNAcylation in Cancer Biology: Linking Metabolism and Signaling

Christina M. Ferrer et al.

JOURNAL OF MOLECULAR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

CHK2 stability is regulated by the E3 ubiquitin ligase SIAH2

C. Garcia-Limones et al.

ONCOGENE (2016)

Review Oncology

From Krebs to clinic: glutamine metabolism to cancer therapy

Brian J. Altman et al.

NATURE REVIEWS CANCER (2016)

Article Oncology

Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate

Preethi Korangath et al.

CLINICAL CANCER RESEARCH (2015)

Article Biochemistry & Molecular Biology

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

Emily D. Montal et al.

MOLECULAR CELL (2015)

Review Cell Biology

Metabolic pathways promoting cancer cell survival and growth

Lindsey K. Boroughs et al.

NATURE CELL BIOLOGY (2015)

Article Cell Biology

mTORC2 controls cancer cell survival by modulating gluconeogenesis

M. W. Khan et al.

CELL DEATH DISCOVERY (2015)

Article Biochemistry & Molecular Biology

Cross-talk between Two Essential Nutrient-sensitive Enzymes O-GlcNAc TRANSFERASE ( OGT) AND AMP-ACTIVATED PROTEIN KINASE ( AMPK)

John W. Bullen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

Kivanc Birsoy et al.

NATURE (2014)

Review Pharmacology & Pharmacy

Targeting nuclear kinases in cancer: Development of cell cycle kinase inhibitors

Todd M. Pitts et al.

PHARMACOLOGY & THERAPEUTICS (2014)

Review Biochemistry & Molecular Biology

O-GlcNAc in cancer biology

Zhiyuan Ma et al.

AMINO ACIDS (2013)

Article Multidisciplinary Sciences

Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma

Ruihua Ma et al.

NATURE COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

The E2F-1 associated retinoblastoma-susceptibility gene product is modified by O-GlcNAc

Lance Wells et al.

AMINO ACIDS (2011)

Review Cell Biology

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

Sophia Y. Lunt et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)

Article Biochemistry & Molecular Biology

Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

Sang Yoon Park et al.

EMBO JOURNAL (2010)

Article Cell Biology

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

Tanja van Harn et al.

GENES & DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Structure and Activation Mechanism of the CHK2 DNA Damage Checkpoint Kinase

Zhenjian Cai et al.

MOLECULAR CELL (2009)

Review Oncology

Cellular mechanisms of tumour suppression by the retinoblastoma gene

Deborah L. Burkhart et al.

NATURE REVIEWS CANCER (2008)

Review Multidisciplinary Sciences

Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins

Gerald W. Hart et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage

Yasumichi Inoue et al.

EMBO JOURNAL (2007)

Article Biochemistry & Molecular Biology

PCK1 and PCK2 as candidate diabetes and obesity genes

Elmus G. Beale et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2007)

Review Biochemistry & Molecular Biology

Cell cycle control and beyond: emerging roles for the retinoblastoma gene family

C. Genovese et al.

ONCOGENE (2006)

Review Endocrinology & Metabolism

Disregulated glyceroneogenesis:: PCK1 as a candidate diabetes and obesity gene

EG Beale et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2004)

Review Biochemistry & Molecular Biology

O-GlcNAc a sensor of cellular state:: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress

NE Zachara et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2004)

Article Cell Biology

Acetylation control of the retinoblastoma tumour-suppressor protein

HM Chan et al.

NATURE CELL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism

P She et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)