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Bart W. Hoogenboom et al.
PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS (2021)
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The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes
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JOURNAL OF CELL BIOLOGY (2020)
Karyopherin enrichment at the nuclear pore complex attenuates Ran permeability
Suncica Barbato et al.
JOURNAL OF CELL SCIENCE (2020)
XPO1-dependent nuclear export as a target for cancer therapy
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JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Modeling the nucleoporins that form the hairy pores
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BIOCHEMICAL SOCIETY TRANSACTIONS (2020)
Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging
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NEURON (2020)
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Proteomics of nucleocytoplasmic partitioning
Thao Nguyen et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2019)
Homeostasis of soluble proteins and the proteasome post nuclear envelope reformation in mitosis
Menno Spits et al.
JOURNAL OF CELL SCIENCE (2019)
Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chperone
Abhilash Padavannil et al.
ELIFE (2019)
The cargo spectrum of nuclear transport receptors
Imke Baade et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation
Wenjuan Zhang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity
Steven M. Heaton et al.
CELLS (2019)
Surface Properties Determining Passage Rates of Proteins through Nuclear Pores
Steffen Frey et al.
CELL (2018)
Karyopherins in cancer
Tolga Cagatay et al.
CURRENT OPINION IN CELL BIOLOGY (2018)
Xpo7 is a broad-spectrum exportin and a nuclear import receptor
Metin Aksu et al.
JOURNAL OF CELL BIOLOGY (2018)
Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/1-14_Asf1a Complex and Its Histone H3 Tail Binding
Jungmin Yoon et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Aggregation, Phase Separation and Spatial Morphologies of the Assemblies of FG Nucleoporins
Anton Zilman
JOURNAL OF MOLECULAR BIOLOGY (2018)
Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells
Xiangpeng Hu et al.
ONCOLOGY LETTERS (2018)
Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors
Piau Siong Tan et al.
CELL REPORTS (2018)
Integrative structure and functional anatomy of a nuclear pore complex
Seung Joong Kim et al.
NATURE (2018)
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease
Bahareh Eftekharzadeh et al.
NEURON (2018)
Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p
Masako Koyama et al.
GENES TO CELLS (2017)
Karyopherins regulate nuclear pore complex barrier and transport function
Larisa E. Kapinos et al.
JOURNAL OF CELL BIOLOGY (2017)
Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases
Hong Joo Kim et al.
NEURON (2017)
Floppy but not sloppy: Interaction mechanism of FG-nucleoporins and nuclear transport receptors
Iker Valle Aramburu et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)
Simple rules for passive diffusion through the nuclear pore complex
Benjamin L. Timney et al.
JOURNAL OF CELL BIOLOGY (2016)
The Multiple Faces of Disordered Nucleoporins
Edward A. Lemke
JOURNAL OF MOLECULAR BIOLOGY (2016)
Structural Biology and Regulation of Protein Import into the Nucleus
Mary Christie et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy
Yusuke Sakiyama et al.
NATURE NANOTECHNOLOGY (2016)
CAS (CSE1L) signaling pathway in tumor progression and its potential as a biomarker and target for targeted therapy
Ming-Chung Jiang
TUMOR BIOLOGY (2016)
A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies
Raphael Zahn et al.
ELIFE (2016)
Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex
Andrei Vovk et al.
ELIFE (2016)
Inhibiting cancer cell hallmark features through nuclear export inhibition
Qingxiang Sun et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2016)
Promiscuous Binding of Karyopherinβ1 Modulates FG Nucleoporin Barrier Function and Expedites NTF2 Transport Kinetics
Raphael S. Wagner et al.
BIOPHYSICAL JOURNAL (2015)
The Nuclear Proteome of a Vertebrate
Martin Wuehr et al.
CURRENT BIOLOGY (2015)
RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus
Jessie M. Sutherland et al.
FASEB JOURNAL (2015)
Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex
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MOLECULAR BIOLOGY OF THE CELL (2015)
In situ structural analysis of the human nuclear pore complex
Alexander von Appen et al.
NATURE (2015)
Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell-lines
Mingcong Wang et al.
PROTEOMICS (2015)
Structure and gating of the nuclear pore complex
Matthias Eibauer et al.
NATURE COMMUNICATIONS (2015)
Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export
Sarah A. Port et al.
CELL REPORTS (2015)
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
Koray Kirli et al.
ELIFE (2015)
Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
Alan R. Lowe et al.
ELIFE (2015)
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Hermann Broder Schmidt et al.
ELIFE (2015)
How to operate a nuclear pore complex by Kap-centric control
Roderick Y. H. Lim et al.
NUCLEUS (2015)
How to operate a nuclear pore complex by Kap-centric control
Roderick Y. H. Lim et al.
NUCLEUS (2015)
Karyopherin-Centric Control of Nuclear Pores Based on Molecular Occupancy and Kinetic Analysis of Multivalent Binding with FG Nucleoporins
Larisa E. Kapinos et al.
BIOPHYSICAL JOURNAL (2014)
Transportin-1 and Transportin-2: Protein nuclear import and beyond
Laure Twyffels et al.
FEBS LETTERS (2014)
Importin 8 Regulates the Transport of Mature MicroRNAs into the Cell Nucleus
Yao Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Selective inhibitors of nuclear export (SINE)- a novel class of anti-cancer agents
Kaushal Parikh et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)
Selective transport control on molecular velcro made from intrinsically disordered proteins
Kai D. Schleicher et al.
NATURE NANOTECHNOLOGY (2014)
Structural basis for nuclear import of splicing factors by human Transportin 3
Goedele N. Maertens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Viral Subversion of Nucleocytoplasmic Trafficking
Melanie L. Yarbrough et al.
TRAFFIC (2014)
Biological Significance of the Importin-β Family-Dependent Nucleocytoplasmic Transport Pathways
Makoto Kimura et al.
TRAFFIC (2014)
NESmapper: Accurate Prediction of Leucine-Rich Nuclear Export Signals Using Activity-Based Profiles
Shunichi Kosugi et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Unusual biophysics of intrinsically disordered proteins
Vladimir N. Uversky
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)
Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins
Li-Chun Tu et al.
EMBO JOURNAL (2013)
Facilitated aggregation of FG nucleoporins under molecular crowding conditions
Sigrid Milles et al.
EMBO REPORTS (2013)
Several Phenylalanine-Glycine Motives in the Nucleoporin Nup214 Are Essential for Binding of the Nuclear Export Receptor CRM1
Stephanie Roloff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Structural basis for cooperativity of CRM1 export complex formation
Thomas Monecke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Viscoelasticity of Thin Biomolecular Films: A Case Study on Nucleoporin Phenylalanine-Glycine Repeats Grafted to a Histidine-Tag Capturing QCM-D Sensor
Nico B. Eisele et al.
BIOMACROMOLECULES (2012)
The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model
Bastian B. Huelsmann et al.
CELL (2012)
Characterization of BRCA1 Protein Targeting, Dynamics, and Function at the Centrosome A ROLE FOR THE NUCLEAR EXPORT SIGNAL, CRM1, AND AURORA A KINASE
Kirsty M. Brodie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Nucleocytoplasmic Transport: A Role for Nonspecific Competition in Karyopherin-Nucleoporin Interactions
Jaclyn Tetenbaum-Novatt et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3
Hsu-Wen Chao et al.
NUCLEIC ACIDS RESEARCH (2012)
Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes
Rafael L. Schoch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Regulation of nucleocytoplasmic trafficking of viral proteins: An integral role in pathogenesis?
Alex J. Fulcher et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
The importin β binding domain as a master regulator of nucleocytoplasmic transport
Kaylen Lott et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Nuclear import by karyopherin-βs: Recognition and inhibition
Yuh Min Chook et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Fluorescence Correlation Spectroscopy of Intact Nuclear Pore Complexes
Francesco Cardarelli et al.
BIOPHYSICAL JOURNAL (2011)
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet et al.
BRIEFINGS IN BIOINFORMATICS (2011)
Evolution of the Karyopherin-β Family of Nucleocytoplasmic Transport Factors; Ancient Origins and Continued Specialization
Amanda J. O'Reilly et al.
PLOS ONE (2011)
An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat Proteins
Christian Kappel et al.
BIOPHYSICAL JOURNAL (2010)
An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1
Masako Koyama et al.
EMBO JOURNAL (2010)
An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
Rafal Pawlowski et al.
EMBO JOURNAL (2010)
Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors
Nico B. Eisele et al.
EMBO REPORTS (2010)
A Bimodal Distribution of Two Distinct Categories of Intrinsically Disordered Structures with Separate Functions in FG Nucleoporins
Justin Yamada et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport
David Grunwald et al.
NATURE (2010)
The nuclear pore complex: bridging nuclear transport and gene regulation
Caterina Strambio-De-Castillia et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis
K-S Chan et al.
CELL DEATH & DISEASE (2010)
Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7
Georgia Chachami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Spatial Distribution and Mobility of the Ran GTPase in Live Interphase Cells
Asmahan Abu-Arish et al.
BIOPHYSICAL JOURNAL (2009)
Nucleocytoplasmic transport: a thermodynamic mechanism
Ronen Benjamine Kopito et al.
HFSP JOURNAL (2009)
Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α
Shunichi Kosugi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Apoptotic histone modification inhibits nuclear transport by regulating RCC1
Chi-Hang Wong et al.
NATURE CELL BIOLOGY (2009)
A High-Resolution Structure of the Pre-microRNA Nuclear Export Machinery
Chimari Okada et al.
SCIENCE (2009)
Nuclear translocation of hypoxia-inducible factors (HIFs):: Involvement of the classical importin α/β pathway
Reinhard Depping et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Molecular basis for the recognition of snurportin 1 by importin β
Gregory Mitrousis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study
Thomas Dange et al.
JOURNAL OF CELL BIOLOGY (2008)
The RanGTP gradient - a GPS for the mitotic spindle
Petr Kalab et al.
JOURNAL OF CELL SCIENCE (2008)
Kap95p Binding Induces the Switch Loops of RanGDP to Adopt the GTP-Bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Jade K. Forwood et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Spatial and temporal coordination of mitosis by Ran GTPase
Paul R. Clarke et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Crossing the nuclear envelope: Hierarchical regulation of nucleocytoplasmic transport
Laura J. Terry et al.
SCIENCE (2007)
Hyperosmotic stress signaling to the nucleus disrupts the ran gradient and the production of RanGTP
Joshua B. Kelley et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Nanomechanical basis of selective gating by the nuclear pore complex
Roderick Y. H. Lim et al.
SCIENCE (2007)
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography
Martin Beck et al.
NATURE (2007)
Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation
Masayuki Kanai et al.
NATURE CELL BIOLOGY (2007)
Classical nuclear localization signals:: Definition, function, and interaction with importin α
Allison Lange et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Molecular mechanism of the nuclear protein import cycle
Murray Stewart
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Nuclear import time and transport efficiency depend on importin β concentration
Weidong Yang et al.
JOURNAL OF CELL BIOLOGY (2006)
Rules for nuclear localization sequence recognition by karyopherinβ2
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CELL (2006)
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Karyopherin flexibility in nucleocytoplasmic transport
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CURRENT OPINION IN STRUCTURAL BIOLOGY (2006)
Transportin is a major nuclear import receptor for c-Fos - A novel mode of cargo interaction
M Arnold et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Binding dynamics of isolated nucleoporin repeat regions to importin-β
TA Isgro et al.
STRUCTURE (2005)
Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs
R Yi et al.
RNA (2005)
Nuclear transport of single molecules:: dwell times at the nuclear pore complex
U Kubitscheck et al.
JOURNAL OF CELL BIOLOGY (2005)
Transportin2 functions as importin and mediates nuclear import of HuR
S Güttinger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Conformational variability of nucleo-cytoplasmic transport factors
N Fukuhara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3
C Gwizdek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nuclear export of microRNA precursors
E Lund et al.
SCIENCE (2004)
Importin α:: a multipurpose nuclear-transport receptor
DS Goldfarb et al.
TRENDS IN CELL BIOLOGY (2004)
Imaging of single-molecule translocation through nuclear pore complexes
WD Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Paired-type homeodomain transcription factors are imported into the nucleus by karyopherin 13
JE Ploski et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The structure of importin-β bound to SREBP-2:: Nuclear import of a transcription factor
SJ Lee et al.
SCIENCE (2003)
A novel splicing regulator shares a nuclear import pathway with SR proteins
MC Lai et al.
EMBO JOURNAL (2003)
Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation
D Görlich et al.
EMBO JOURNAL (2003)
The strategy for coupling the RanGTP gradient to nuclear protein export
A Becskei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
P Kalab et al.
SCIENCE (2002)
Transportin-SR2 mediates nuclear import of phosphorylated SR proteins
MC Lai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Proteomic analysis of nucleoporin interacting proteins
NPC Allen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Importin 13:: a novel mediator of nuclear import and export
JM Mingot et al.
EMBO JOURNAL (2001)
Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)
L Renault et al.
CELL (2001)
Finding nuclear localization signals
M Cokol et al.
EMBO REPORTS (2000)
Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2
SM Plafker et al.
EMBO JOURNAL (2000)
Crystallization and initial X-ray diffraction characterization of complexes of FxFG nucleoporin repeats with nuclear transport factors
R Bayliss et al.
JOURNAL OF STRUCTURAL BIOLOGY (2000)
Exportin 4:: a mediator of a novel nuclear export pathway in higher eukaryotes
G Lipowsky et al.
EMBO JOURNAL (2000)
Structural basis for the interaction between FxFG nucleoporin repeats and importin-β in nuclear trafficking
R Bayliss et al.
CELL (2000)
Nuclear import of the Ran exchange factor, RCC1, is mediated by at least two distinct mechanisms
ME Nemergut et al.
JOURNAL OF CELL BIOLOGY (2000)
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