4.6 Article

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

Yanhui Hu et al.

Summary: The FlyRNAi database at DRSC/TRiP provides online resources for functional genomics studies, focusing on Drosophila melanogaster. It includes gene-centric, reagent-centric, and data-centric resources to aid in ortholog mapping, identifying RNAi and CRISPR sgRNA reagents, and visualizing transcriptomics data and protein interactions. These features help biological and biomedical researchers efficiently integrate and analyze information for Drosophila and other species in functional genomics workflows.

NUCLEIC ACIDS RESEARCH (2021)

Article Clinical Neurology

Phosphorylated tau interactome in the human Alzheimer's disease brain

Eleanor Drummond et al.

Article Biochemistry & Molecular Biology

Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease

Hendrik Wesseling et al.

Article Immunology

Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice

David Brenner et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Article Biochemistry & Molecular Biology

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue

Peng Zhao et al.

Article Neurosciences

A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies

Caterina Giacomini et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

Daichao Xu et al.

Article Biochemical Research Methods

Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease

Measho H. Abreha et al.

PROTEOMICS (2018)

Review Biochemistry & Molecular Biology

Degradation or aggregation: the ramifications of post-translational modifications on tau

Seoyoung Park et al.

BMB REPORTS (2018)

Review Neurosciences

TBK1: a new player in ALS linking autophagy and neuroinflammation

James A. Oakes et al.

MOLECULAR BRAIN (2017)

Article Biochemistry & Molecular Biology

Biochemical and Behavioral Evaluation of Human MAPT Mutations in Transgenic Drosophila melanogaster

Mohammad Haddadi et al.

BIOCHEMICAL GENETICS (2016)

Article Geriatrics & Gerontology

TBK1 is associated with ALS and ALS-FTD in Sardinian patients

Giuseppe Borghero et al.

NEUROBIOLOGY OF AGING (2016)

Review Pharmacology & Pharmacy

Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies

Maroof Hasan et al.

PHARMACOLOGICAL RESEARCH (2016)

Review Biochemistry & Molecular Biology

Human TBK1: A Gatekeeper of Neuroinflammation

Liyana Ahmad et al.

TRENDS IN MOLECULAR MEDICINE (2016)

Article Neurosciences

Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease

Amit K. Chouhan et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)

Article Ophthalmology

Copy Number Variations of TBK1 in Australian Patients With Primary Open-Angle Glaucoma

Mona S. Awadalla et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2015)

Article Biochemistry & Molecular Biology

TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation

Gen Matsumoto et al.

HUMAN MOLECULAR GENETICS (2015)

Article Neurosciences

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Axel Freischmidt et al.

NATURE NEUROSCIENCE (2015)

Article Geriatrics & Gerontology

Novel TBK1 truncating mutation in a familial amyotrophic lateral sclerosis patient of Chinese origin

Kelly L. Williams et al.

NEUROBIOLOGY OF AGING (2015)

Article Clinical Neurology

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

Ilse Gijselinck et al.

NEUROLOGY (2015)

Article Multidisciplinary Sciences

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis

Smitha Pillai et al.

NATURE COMMUNICATIONS (2015)

Article Clinical Neurology

Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration

Naomi Kouri et al.

ACTA NEUROPATHOLOGICA (2014)

Article Ophthalmology

TBK1 Gene Duplication and Normal-Tension Glaucoma

Robert Ritch et al.

JAMA OPHTHALMOLOGY (2014)

Review Cell Biology

Tau protein kinases: Involvement in Alzheimer's disease

Ludovic Martin et al.

AGEING RESEARCH REVIEWS (2013)

Article Biochemistry & Molecular Biology

An inhibitor of the protein kinases TBK1 and IKK-ε improves obesity-related metabolic dysfunctions in mice

Shannon M. Reilly et al.

NATURE MEDICINE (2013)

Article Cell Biology

Crystal Structure and Mechanism of Activation of TANK-Binding Kinase 1

Amede Larabi et al.

CELL REPORTS (2013)

Review Cell Biology

The Pivotal Role of TBK1 in Inflammatory Responses Mediated by Macrophages

Tao Yu et al.

MEDIATORS OF INFLAMMATION (2012)

Article Multidisciplinary Sciences

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Xiaolei Ma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

Yasuo Tanaka et al.

SCIENCE SIGNALING (2012)

Article Biochemistry & Molecular Biology

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

Yi-Hung Ou et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

TBK1 Mediates Crosstalk Between the Innate Immune Response and Autophagy

Hilla Weidberg et al.

SCIENCE SIGNALING (2011)

Article Clinical Neurology

Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation

S. G. Lindquist et al.

EUROPEAN JOURNAL OF NEUROLOGY (2008)

Article Biochemistry & Molecular Biology

The selectivity of protein kinase inhibitors: a further update

Jenny Bain et al.

BIOCHEMICAL JOURNAL (2007)

Review Cell Biology

Analysis of protein complexes using mass spectrometry

Anne-Claude Gingras et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Neurosciences

S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila

Michelle L. Steinhilb et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2007)

Article Biochemistry & Molecular Biology

Large-scale mapping of human protein-protein interactions by mass spectrometry

Rob M. Ewing et al.

MOLECULAR SYSTEMS BIOLOGY (2007)

Review Biochemistry & Molecular Biology

Mass spectrometry-based proteomics turns quantitative

SE Ong et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Immunology

IKKε and TBK1 are essential components of the IRF3 signaling pathway

KA Fitzgerald et al.

NATURE IMMUNOLOGY (2003)

Article Multidisciplinary Sciences

Tauopathy in Drosophila:: Neurodegeneration without neurofibrillary tangles

CW Wittmann et al.

SCIENCE (2001)

Article Multidisciplinary Sciences

Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

AD Alonso et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

14-3-3ζ is an effector of tau protein phosphorylation

M Hashiguchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)