Frozen-thawed embryo transfers: time to adopt a more natural approach?

The increasing use of frozen-thawed embryo transfer (FET) cycles has magnified the focus on endometrial preparation protocols in assisted reproduction. Emerging evidence suggests that natural cycle (NC) FETs are associated with improved outcomes, and that providers should consider increasing the utilization of NC FET at the expense of the currently favored artificial cycle (AC) FET as primary method for endometrial preparation.

Automated summary

The increasing use of frozen-thawed embryo transfer (FET) cycles has brought more attention to endometrial preparation protocols in assisted reproduction. Emerging evidence suggests that natural cycle (NC) FETs may lead to better outcomes, leading to a recommendation for healthcare providers to consider increasing the utilization of NC FET over the favored artificial cycle (AC) FET for endometrial preparation.