Facile Preparation of ZIF-8 MOF Coated Mesoporous Magnetic Nanoarticles to Provide a Magnetic Solid Phase Extraction Platform

In this work, zeolitic imidazolate framework (ZIF-8) coated mesoporous magnetic nanoparticles (Fe3O4@PDA@mSiO(2)@ZIF-8) were prepared through a facile and efficient strategy and used as a magnetic solid phase extraction platform for phthalates detection. Polydopamine (PDA) not only provides a hydrophilic layer, but also possesses pi electrons for aromatic compounds recognition; mSiO(2) endows the nanoparticles with large surface area and regular channels, which facilitates the rapid transport of phthalates. The prepared Fe3O4@PDA@mSiO(2)@ZIF-8 with imposed properties showed ultrahigh efficiency and reusability for phthalates determination in human plasma samples. The linearity range was 50-8000 ng/mL, limits of detection were between 50-80 ng/mL, the intra-day RSDs were lower than 4.8%, inter-day RSDs were lower than 6.7%, the recoveries ranged from 90 to 107%. The new prepared nanoparticles displayed potential performance for aromatic compounds detection.

Automated summary

A magnetic solid phase extraction platform was developed using zeolitic imidazolate framework-coated mesoporous magnetic nanoparticles for phthalates detection. The nanoparticles showed high efficiency and reusability in determining phthalates in human plasma samples, with potential for aromatic compounds detection applications.