4.7 Article

Engineering of Multiple Modules to Improve Amorphadiene Production in Bacillus subtilis Using CRISPR-Cas9

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biotechnology & Applied Microbiology

Positioning Bacillus subtilis as terpenoid cell factory

H. Pramastya et al.

Summary: Bacillus subtilis is being developed into terpenoids cell factories due to its safe status and high isoprene precursor biosynthesis capacity. This review provides insights into the MEP pathway enzymes, isomerization of C5 isoprene precursors, and steps to improve terpenoids production in B. subtilis. The study also discusses genetic tools and strategies for further development of terpenoid cell factories in B. subtilis.

JOURNAL OF APPLIED MICROBIOLOGY (2021)

Article Biochemical Research Methods

High level production of amorphadiene using Bacillus subtilis as an optimized terpenoid cell factory

Hegar Pramastya et al.

Summary: By overexpressing amorphadiene synthase and providing sufficient substrate in Bacillus subtilis, a significant increase in amorphadiene production was achieved, providing a feasible pathway for artemisinin production.

NEW BIOTECHNOLOGY (2021)

Article Biotechnology & Applied Microbiology

A regulated synthetic operon facilitates stable overexpression of multigene terpenoid pathway in Bacillus subtilis

Ingy I. Abdallah et al.

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2020)

Review Biochemistry & Molecular Biology

Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids

Dinesh A. Nagegowda et al.

PLANT SCIENCE (2020)

Article Agriculture, Multidisciplinary

Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering

Yafeng Song et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)

Article Biochemical Research Methods

CRISPR-dCas9 Mediated Cytosine Deaminase Base Editing in Bacillus subtilis

Sili Yu et al.

ACS SYNTHETIC BIOLOGY (2020)

Article Biotechnology & Applied Microbiology

Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica

Monireh Marsafari et al.

METABOLIC ENGINEERING COMMUNICATIONS (2020)

Article Biochemical Research Methods

Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7

Yanwei Ma et al.

ACS SYNTHETIC BIOLOGY (2019)

Review Medicine, Research & Experimental

CRISPR-Cas9 system: A new-fangled dawn in gene editing

Darshana Gupta et al.

LIFE SCIENCES (2019)

Article Biotechnology & Applied Microbiology

Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli

Sudha Shukal et al.

METABOLIC ENGINEERING (2019)

Article Multidisciplinary Sciences

CRISPR-Cas9 In Situ engineering of subtilisin E in Bacillus subtilis

Marcus A. Price et al.

PLOS ONE (2019)

Article Biochemical Research Methods

Modular Pathway Engineering of Bacillus subtilis To Promote De Novo Biosynthesis of Menaquinone-7

Shaomei Yang et al.

ACS SYNTHETIC BIOLOGY (2019)

Article Multidisciplinary Sciences

Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering

Ingy I. Abdallah et al.

SCIENTIFIC REPORTS (2018)

Article Microbiology

A Highly Efficient CRISPR-Cas9-Mediated Large Genomic Deletion in Bacillus subtilis

Younju So et al.

FRONTIERS IN MICROBIOLOGY (2017)

Article Biochemistry & Molecular Biology

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis

Byoung-Mo Koo et al.

CELL SYSTEMS (2017)

Review Biotechnology & Applied Microbiology

Engineering yeast metabolism for production of terpenoids for use as perfume ingredients, pharmaceuticals and biofuels

Yueping Zhang et al.

FEMS YEAST RESEARCH (2017)

Article Biotechnology & Applied Microbiology

Development of a CRISPR-Cas9 Tool Kit for Comprehensive Engineering of Bacillus subtilis

Adam W. Westbrook et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)

Article Biotechnology & Applied Microbiology

Editing of the Bacillus subtilis Genome by the CRISPR-Cas9 System

Josef Altenbuchner

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)

Article Biotechnology & Applied Microbiology

Enhanced C30 carotenoid production in Bacillus subtilis by systematic overexpression of MEP pathway genes

Dan Xue et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2015)

Review Biotechnology & Applied Microbiology

Current development in genetic engineering strategies of Bacillus species

Huina Dong et al.

MICROBIAL CELL FACTORIES (2014)

Article Biotechnology & Applied Microbiology

Optimization of Amorphadiene Synthesis in Bacillus Subtilis Via Transcriptional, Translational, and Media Modulation

Kang Zhou et al.

BIOTECHNOLOGY AND BIOENGINEERING (2013)

Article Multidisciplinary Sciences

High-level semi-synthetic production of the potent antimalarial artemisinin

C. J. Paddon et al.

NATURE (2013)

Article Biotechnology & Applied Microbiology

Engineering central metabolic modules of Escherichia coli for improving β-carotene production

Jing Zhao et al.

METABOLIC ENGINEERING (2013)

Article Multidisciplinary Sciences

Menaquinone and Iron Are Essential for Complex Colony Development in Bacillus subtilis

Gidi Pelchovich et al.

PLOS ONE (2013)

Article Biotechnology & Applied Microbiology

Simple Cloning via Direct Transformation of PCR Product (DNA Multimer) to Escherichia coli and Bacillus subtilis

Chun You et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2012)

Article Multidisciplinary Sciences

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Patrick J. Westfall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

Parayil Kumaran Ajikumar et al.

SCIENCE (2010)

Article Biotechnology & Applied Microbiology

Carotenoid production in Bacillus subtilis achieved by metabolic engineering

Kazuyuki Yoshida et al.

BIOTECHNOLOGY LETTERS (2009)

Review Plant Sciences

Terpenoid biomaterials

Joerg Bohlmann et al.

PLANT JOURNAL (2008)

Article Chemistry, Multidisciplinary

Direct observation of substrate-enzyme complexation by surface forces measurement

Takehiro Suzuki et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Biotechnology & Applied Microbiology

Production of Alcaligenes faecalis penicillin G acylase in Bacillus subtilis WB600 (pMA5) fed with partially hydrolyzed starch

Min Zhang et al.

ENZYME AND MICROBIAL TECHNOLOGY (2006)

Article Biotechnology & Applied Microbiology

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

VJJ Martin et al.

NATURE BIOTECHNOLOGY (2003)