☆ 4.7 Editorial Material

Treatment Strategies for Patients With Immune-Mediated Inflammatory Diseases

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Designing and undertaking randomised implementation trials: guide for researchers

Luke Wolfenden et al.

Summary: Implementation science focuses on improving the quality of randomized trials of implementation strategies and addressing current limitations. This study aims to provide guidance on the development, conduct, and reporting of these trials to advance rigorous conduct and reporting in the field.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Health Care Sciences & Services

Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation

Irina A. Tikhonova et al.

HEALTH TECHNOLOGY ASSESSMENT (2021)

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Article Gastroenterology & Hepatology

The optimal management of anti-drug antibodies to infliximab and identification of anti-drug antibody values for clinical outcomes in patients with inflammatory bowel disease

Neasa Mc Gettigan et al.

Summary: The study aimed to identify optimal management strategies for anti-drug antibodies (ADAs) in patients receiving infliximab (IFX) to prevent therapy discontinuation. Results showed that increasing IFX dosage and adjusting combination therapy can lower rates of discontinuation of IFX, with significant cut-off values for ADA trough levels and important clinical outcomes identified through ROC curve analysis.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2021)

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Review Gastroenterology & Hepatology