4.6 Editorial Material

Evidence and Recommendations for Uninterrupted Versus Interrupted Oral Anticoagulation in Patients Undergoing Percutaneous Coronary Intervention

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Article Cardiac & Cardiovascular Systems

Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention A North American Perspective: 2021 Update

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Summary: Patients with atrial fibrillation undergoing PCI face challenges in optimal antithrombotic management due to the need for oral anticoagulation and dual antiplatelet therapy. Updated recommendations suggest the use of non-vitamin K antagonist oral anticoagulants and a double therapy approach after the peri-PCI period, with the duration of dual therapy depending on the patient's ischemic and bleeding risk profile. Triple therapy with aspirin may be considered in patients at increased thrombotic risk but with an acceptable risk of bleeding.

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Uninterrupted Oral Anticoagulant Therapy in Patients Undergoing Unplanned Percutaneous Coronary Intervention

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Summary: The study found that interrupted and uninterrupted oral anticoagulant therapy had similar risks for major adverse cardiac events and bleeding complications, with uninterrupted therapy associated with shorter hospitalization duration.

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