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Alejandro Pizzoni et al.
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David Merrick et al.
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Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation
S. Fu et al.
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Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model
Rebecca V. Walker et al.
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Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis
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Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP-1-mediated endocytosis
Clarissa R. Coveney et al.
FASEB JOURNAL (2018)
TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
Michele A. Corrigan et al.
SCIENTIFIC REPORTS (2018)
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium
Xiaowen Liu et al.
ELIFE (2018)
Structure of the human PKD1-PKD2 complex
Qiang Su et al.
SCIENCE (2018)
Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium
Gillian P. Johnson et al.
JOURNAL OF CELL SCIENCE (2018)
Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis
Georgia Dalagiorgou et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Primary Cilium-Dependent Signaling Mechanisms
Rajasekharreddy Pala et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes
Z. He et al.
OSTEOARTHRITIS AND CARTILAGE (2016)
Regulation of Polycystin-1 Function by Calmodulin Binding
Nicholas Doerr et al.
PLOS ONE (2016)
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner
Vladimir G. Gainullin et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
The growth plate's response to load is partially mediated by mechano-sensing via the chondrocytic primary cilium
Yoach Rais et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage
Jerome Irianto et al.
JOURNAL OF BIOMECHANICS (2014)
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes
C. L. Thompson et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
OFD1 and Flotillins Are Integral Components of a Ciliary Signaling Protein Complex Organized by Polycystins in Renal Epithelia and Odontoblasts
Stephanie Jerman et al.
PLOS ONE (2014)
Osteoblast-Specific Deletion of Pkd2 Leads to Low-Turnover Osteopenia and Reduced Bone Marrow Adiposity
Zhousheng Xiao et al.
PLOS ONE (2014)
TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading
Christopher J. O'Conor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet
Christopher J. O'Conor et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis
Georgia Dalagiorgou et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Reduced Ciliary Polycystin-2 in Induced Pluripotent Stem Cells from Polycystic Kidney Disease Patients with PKD1 Mutations
Benjamin S. Freedman et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)
Primary cilia are specialized calcium signalling organelles
Markus Delling et al.
NATURE (2013)
Osteoarthritis as a disease of mechanics
D. T. Felson
OSTEOARTHRITIS AND CARTILAGE (2013)
The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes
Ann K. Rosenthal et al.
ARTHRITIS RESEARCH & THERAPY (2013)
Intracellular calcium release modulates polycystin-2 trafficking
Ayako Miyakawa et al.
BMC NEPHROLOGY (2013)
Primary cilia elongation in response to interleukin-1 mediates the inflammatory response
A. K. T. Wann et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes
Angus K. T. Wann et al.
FASEB JOURNAL (2012)
Calcium-induced Conformational Changes in C-terminal Tail of Polycystin-2 Are Necessary for Channel Gating
Andjelka S. Celic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis
C. -F Chang et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Chondrocyte primary cilia shorten in response to osmotic challenge and are sites for endocytosis
D. R. Rich et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Orientation of Primary Cilia of Articular Chondrocytes in Three-Dimensional Space
Cornelia E. Farnum et al.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2011)
Mechanical loading modulates chondrocyte primary cilia incidence and length
Susan R. McGlashan et al.
CELL BIOLOGY INTERNATIONAL (2010)
Polycystin-1 Surface Localization Is Stimulated by Polycystin-2 and Cleavage at the G Protein-coupled Receptor Proteolytic Site
Hannah C. Chapin et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
The Role of Transient Receptor Potential Cation Channels in Ca2+ Signaling
Maarten Gees et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Functional Characterization of TRPV4 as an Osmotically Sensitive Ion Channel in Porcine Articular Chondrocytes
Mimi N. Phan et al.
ARTHRITIS AND RHEUMATISM (2009)
Cartilage Abnormalities Associated with Defects of Chondrocytic Primary Cilia in Bardet-Biedl Syndrome Mutant Mice
Anjan P. Kaushik et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2009)
TRPP2 and TRPV4 form a polymodal sensory channel complex
Michael Koetttgen et al.
JOURNAL OF CELL BIOLOGY (2008)
Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression
T. T. Chowdhury et al.
BIORHEOLOGY (2008)
Cyclic equibiaxial tensile strain induces both anabolic and catabolic responses in articular chondrocytes
J. Huang et al.
GENE (2007)
Development of the post-natal growth plate requires intraflagellar transport proteins
Buer Song et al.
DEVELOPMENTAL BIOLOGY (2007)
Intraflagellar transport is essential for endochondral bone formation
Courtney J. Haycraft et al.
DEVELOPMENT (2007)
Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression
T. T. Chowdhury et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Primary cilia of human endothelial cells disassemble under laminar shear stress
C Iomini et al.
JOURNAL OF CELL BIOLOGY (2004)
Integrin-dependent signal cascades in chondrocyte mechanotransduction
SJ Millward-Sadler et al.
ANNALS OF BIOMEDICAL ENGINEERING (2004)
The renal cell primary cilium functions as a flow sensor
HA Praetorius et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2003)
Expression of polycystin-1 C-terminal fragment enhances the ATP-induced Ca2+ release in human kidney cells
G Aguiari et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Bending the primary cilium opens Ca2+-sensitive intermediate-conductance K+ channels in MDCK cells
HA Praetorius et al.
JOURNAL OF MEMBRANE BIOLOGY (2003)
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
SM Nauli et al.
NATURE GENETICS (2003)
Bending the MDCK cell primary cilium increases intracellular calcium
HA Praetorius et al.
JOURNAL OF MEMBRANE BIOLOGY (2001)
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
C Boulter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel
DH Vandorpe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Altered electrophysiological responses to mechanical stimulation and abnormal signalling through α5β1 integrin in chondrocytes from osteoarthritic cartilage
SJ Millward-Sadler et al.
OSTEOARTHRITIS AND CARTILAGE (2000)
Cardiac defects and renal failure in mice with targeted mutations in Pkd2
GQ Wu et al.
NATURE GENETICS (2000)