4.7 Article

Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer's Disease Brains

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Summary: Alzheimer's disease is the most common neurodegenerative disease worldwide, characterized by neurofibrillary tangles and amyloid beta accumulation. Vascular risk factors may lead to dysregulation of the neurovascular unit, contributing to A beta accumulation and neurodegeneration. Therapeutic approaches targeting abnormal A beta levels have had limited success in improving cognition.

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