4.7 Review

Post-Transcriptional Regulation of Gnrhr: A Checkpoint for Metabolic Control of Female Reproduction

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi

Melody Allensworth-James et al.

Summary: Leptin signaling plays a crucial role in regulating energy homeostasis through leptin receptors in the brain, particularly targeting specific transcription factors within pituitary cells. The sex-dependent mechanism of action on somatotropes involves posttranscriptional control of Pou1f1 messenger RNA in females. The interaction between Musashi1 and Pou1f1 mRNA suggests a potential mechanism for coordinating somatotrope function with metabolic status in response to leptin stimulation.

ENDOCRINOLOGY (2021)

Review Cell Biology

Gene regulation by long non-coding RNAs and its biological functions

Luisa Statello et al.

Summary: Recent studies have shed new light on the biogenesis and functions of long non-coding RNAs (lncRNAs), showcasing their diverse roles in gene regulation and signaling pathways, particularly in the contexts of neuronal disorders, immune responses, and cancer. The discovery of unique biogenesis pathways and subcellular localizations of lncRNAs has opened up potential therapeutic avenues for targeting lncRNAs in various biological and pathophysiological conditions.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Review Immunology

Control of RNA Stability in Immunity

Shizuo Akira et al.

Summary: RBPs play a crucial role in regulating mRNA turnover and translation by binding cis-regulatory elements in mRNA's 3' UTRs. They can collaboratively or competitively bind the same target mRNA to enhance or dampen regulatory activities. Dysregulation of RBPs can lead to chronic inflammation and autoimmunity.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 39 (2021)

Review Biochemistry & Molecular Biology

Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment

Rebecca Raue et al.

Summary: MiRs in the tumor microenvironment play crucial roles in regulating cancer progression and serve as potential targets for anti-tumor therapy, offering promising new treatment strategies.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Endocrinology & Metabolism

Metabolic signalling to somatotrophs: Transcriptional and post-transcriptional mediators

Melody L. Allensworth-James et al.

JOURNAL OF NEUROENDOCRINOLOGY (2020)

Article Oncology

Anti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells

Jiping Wang et al.

CANCER BIOLOGY & THERAPY (2019)

Review Cell Biology

MicroRNAs in Obesity and Related Metabolic Disorders

Jean-Francois Landrier et al.

Review Oncology

The RNA Binding Protein HuR: A Promising Drug Target for Anticancer Therapy

Mingxia Wu et al.

CURRENT CANCER DRUG TARGETS (2019)

Article Medicine, General & Internal

Leptin Modulates the Expression of miRNAs-Targeting POMC mRNA by the JAK2-STAT3 and PI3K-Akt Pathways

Adel Derghal et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Health Care Sciences & Services

Real-world menstrual cycle characteristics of more than 600,000 menstrual cycles

Jonathan R. Bull et al.

NPJ DIGITAL MEDICINE (2019)

Article Endocrinology & Metabolism

The RNA-Binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH

Tomohiro Terasaka et al.

ENDOCRINOLOGY (2019)

Article Cell Biology

Regulation of reproduction via tight control of gonadotropin hormone levels

Djurdjica Coss

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018)

Article Obstetrics & Gynecology

Elevated circulating micro-ribonucleic acid (miRNA)-200b and miRNA-429 levels in anovulatory women

Iris Eisenberg et al.

FERTILITY AND STERILITY (2017)

Article Medicine, Research & Experimental

Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility

Kashan Ahmed et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Biochemistry & Molecular Biology

Leptin reduces microRNA-122 level in hepatic stellate cells in vitro and in vivo

Xuguang Zhai et al.

MOLECULAR IMMUNOLOGY (2017)

Review Endocrinology & Metabolism

Intrinsic and Regulated Gonadotropin-Releasing Hormone Receptor Gene Transcription in Mammalian Pituitary Gonadotrophs

Marija M. Janjic et al.

FRONTIERS IN ENDOCRINOLOGY (2017)

Article Multidisciplinary Sciences

HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells

Ranganayaki Muralidharan et al.

SCIENTIFIC REPORTS (2017)

Article Cell Biology

Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage

Huizhen Wang et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)

Review Endocrinology & Metabolism

Control of puberty onset and fertility by gonadotropin-releasing hormone neurons

Allan E. Herbison

NATURE REVIEWS ENDOCRINOLOGY (2016)

Article Multidisciplinary Sciences

A regulatory loop between miR-132 and miR-125b involved in gonadotrope cells desensitization to GnRH

Jerome Lannes et al.

SCIENTIFIC REPORTS (2016)

Review Cell Biology

Masashi Signaling in Stem Cells and Cancer

Raymond G. Fox et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 31 (2015)

Article Reproductive Biology

Cell Type-Specific Sexual Dimorphism in Rat Pituitary Gene Expression During Maturation

Ivana Bjelobaba et al.

BIOLOGY OF REPRODUCTION (2015)

Review Endocrinology & Metabolism

Minireview: Activin Signaling in Gonadotropes: What Does the FOX say... to the SMAD?

Jerome Fortin et al.

MOLECULAR ENDOCRINOLOGY (2015)

Article Endocrinology & Metabolism

Rapid Communication: A MicroRNA-132/212 Pathway Mediates GnRH Activation of FSH Expression

Jerome Lannes et al.

MOLECULAR ENDOCRINOLOGY (2015)

Article Biochemistry & Molecular Biology

Gonadotrope-specific Deletion of Dicer Results in Severely Suppressed Gonadotropins and Fertility Defects

Huizhen Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Chemical identity of hypothalamic neurons engaged by leptin in reproductive control

Dhirender V. Ratra et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2014)

Review Cell Biology

Competition and collaboration between RNA-binding proteins and microRNAs

J. J. David Ho et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2014)

Article Biochemistry & Molecular Biology

MicroRNA Expression Profiling of the Porcine Developing Hypothalamus and Pituitary Tissue

Lifan Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Multidisciplinary Sciences

MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility

Hidetoshi Hasuwa et al.

SCIENCE (2013)

Article Endocrinology & Metabolism

Mechanisms underlying the tissue-specific and regulated activity of the Gnrhr promoter in mammals

Anne-Laure Schang et al.

Frontiers in Endocrinology (2012)

Article Biochemistry & Molecular Biology

Postnatal leptin is necessary for maturation of numerous organs in newborn rats

Linda Attig et al.

ORGANOGENESIS (2011)

Article Endocrinology & Metabolism

Nutritional Programming Affects Hypothalamic Organization and Early Response to Leptin

Berengere Coupe et al.

ENDOCRINOLOGY (2010)

Article Multidisciplinary Sciences

Embryonic gonadotropin-releasing hormone signaling is necessary for maturation of the male reproductive axis

Shuping Wen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Cell Biology

Microtranscriptome regulation by gonadotropin-releasing hormone

Tony Yuen et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Article Neurosciences

Gonadotropin-releasing hormone receptor in spinal cord neurons of embryos and adult rats

J. Luis Quintanar et al.

NEUROSCIENCE LETTERS (2009)

Review Biochemistry & Molecular Biology

Diverse molecular functions of Hu proteins

M. N. Hinman et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Review Biochemistry & Molecular Biology

Gonadotropin-releasing hormone: regulation of the GnRH gene

Vien H. Y. Lee et al.

FEBS JOURNAL (2008)

Article Endocrinology & Metabolism

Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression

Andrea C. Wilson et al.

JOURNAL OF ENDOCRINOLOGY (2006)

Article Endocrinology & Metabolism

KiSS-1 neurones are direct targets for leptin in the ob/ob mouse

JT Smith et al.

JOURNAL OF NEUROENDOCRINOLOGY (2006)

Review Endocrinology & Metabolism

Regulation of expression of mammalian gonadotrophin-releasing hormone receptor genes

JP Hapgood et al.

JOURNAL OF NEUROENDOCRINOLOGY (2005)

Article Cell Biology

Regulation of FSHβ and GnRH receptor gene expression in activin receptor II knockout male mice

TR Kumar et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2003)

Article Cell Biology

Transcriptional regulation of the GnRH receptor gene by glucocorticoids

G Maya-Núñez et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2003)

Article Multidisciplinary Sciences

Role for a bidentate ribonuclease in the initiation step of RNA interference

E Bernstein et al.

NATURE (2001)

Article Developmental Biology

Expression of GnRH receptor in mouse and rat testicular germ cells

P Bull et al.

MOLECULAR HUMAN REPRODUCTION (2000)