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B. Baldo et al.
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Miguel Angel Abellanas et al.
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A. R. Esteves et al.
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Arsun Bektas et al.
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Ian F. Harrison et al.
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Sifan Sun et al.
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D. F. Silva et al.
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Akiko Satoh et al.
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Ichiro Akiguchi et al.
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Geetika Garg et al.
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Guan Wang et al.
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Ban Wang et al.
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T. Jayasena et al.
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Luisa Quinti et al.
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T. Zhao et al.
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M. Erburu et al.
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SIRT2 is required for lipopolysaccharide-induced activation of BV2 microglia
Heyu Chen et al.
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Nady Braidy et al.
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The Discovery of a Highly Selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[ 2,3-d] pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson's Disease Model
Paolo Di Fruscia et al.
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Ae Sin Lee et al.
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Toshiaki Inoue et al.
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Vincent Morrisette-Thomas et al.
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Giuseppe Lo Sasso et al.
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Jiangtao Lin et al.
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R. A. Kireev et al.
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Teresa Faria Pais et al.
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Mi Jin Kim et al.
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Ingeborg M. M. van Leeuwen et al.
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Anna Bobrowska et al.
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Vanita Chopra et al.
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Michele M. Maxwell et al.
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Bogdan Beirowski et al.
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Kai Harting et al.
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Judit Pallos et al.
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Bor Luen Tang et al.
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Shaday Michan et al.
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Wenbo Li et al.
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Aberrant expression of cytoskeleton proteins in hippocampus from patients with mesial temporal lobe epilepsy
J. W. Yang et al.
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E Michishita et al.
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G Liszt et al.
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