4.7 Article

Differential Expression of Sphingolipid Metabolizing Enzymes in Spontaneously Hypertensive Rats: A Possible Substrate for Susceptibility to Brain and Kidney Damage

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, General & Internal

Plasma ceramides are associated with outcomes in acute ischemic stroke patients

Tsung-Heng Lee et al.

Summary: This study investigated the plasma levels of S1P and ceramides in acute ischemic stroke patients, finding associations between these lipids and functional outcomes. The dynamic metabolism of ceramides may serve as potential prognostic markers for patients with AIS.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2022)

Article Cardiac & Cardiovascular Systems

Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke

Anja Nitzsche et al.

Summary: This study explores the role of endothelial cell S1P(1) in the naive and ischemic brain as a potential target for cerebrovascular therapy. Endothelial S1P(1) plays a critical vascular protective role in the mouse brain, sustaining endothelial functions and expanding during ischemia. Disruption of this pathway exacerbates brain injury in ischemic stroke models, highlighting the importance of S1P signaling in maintaining perfusion and microvascular patency in the ischemic penumbra.

CIRCULATION RESEARCH (2021)

Review Urology & Nephrology

The global epidemiology of hypertension

Katherine T. Mills et al.

NATURE REVIEWS NEPHROLOGY (2020)

Article Biochemistry & Molecular Biology

Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats

Carla L. Busceti et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2019 Update A Report From the American Heart Association

Emelia J. Benjamin et al.

CIRCULATION (2019)

Article Biochemical Research Methods

Sphingolipidomics Investigation of the Temporal Dynamics after Ischemic Brain Injury

Hsi-Chun Chao et al.

JOURNAL OF PROTEOME RESEARCH (2019)

Article Hematology

Elevated Plasma Ceramides Are Associated With Higher White Matter Hyperintensity Volume-Brief Report

Michelle M. Mielke et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)

Article Clinical Neurology

Plasma Lipid Profiling Identifies Biomarkers of Cerebral Microvascular Disease

Ida Azizkhanian et al.

FRONTIERS IN NEUROLOGY (2019)

Review Biochemistry & Molecular Biology

Ceramide and Regulation of Vascular Tone

Angel Cogolludo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Cell Biology

Sphingolipids and their metabolism in physiology and disease

Yusuf A. Hannun et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Review Cell Biology

Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease

Speranza Rubattu et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Review Endocrinology & Metabolism

Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis

Linda Sasset et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2016)

Article Cardiac & Cardiovascular Systems

Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease

Speranza Rubattu et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Review Biochemistry & Molecular Biology

Sphingolipids in cardiovascular diseases and metabolic disorders

Sonia Borodzicz et al.

LIPIDS IN HEALTH AND DISEASE (2015)

Article Biochemistry & Molecular Biology

Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure

Anna Cantalupo et al.

NATURE MEDICINE (2015)

Review Biochemistry & Molecular Biology

The role of sphingosine-1-phosphate in endothelial barrier function

Brent A. Wilkerson et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)

Article Clinical Neurology

Role of the Sphingosine Metabolism Pathway on Neurons Against Experimental Cerebral Ischemia in Rats

Yu Hasegawa et al.

TRANSLATIONAL STROKE RESEARCH (2013)

Review Biochemistry & Molecular Biology

Ceramide synthases at the centre of sphingolipid metabolism and biology

Thomas D. Mullen et al.

BIOCHEMICAL JOURNAL (2012)

Article Clinical Neurology

Changes in the Cerebrospinal Fluid Ceramide Profile After Subarachnoid Hemorrhage

Fernando D. Testai et al.

STROKE (2012)

Review Pharmacology & Pharmacy

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

Jerold Chun et al.

PHARMACOLOGICAL REVIEWS (2010)

Article Biochemistry & Molecular Biology

Subcellular Origin of Sphingosine 1-Phosphate Is Essential for Its Toxic Effect in Lyase-deficient Neurons

Nadine Hagen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Biochemistry & Molecular Biology

The vascular S1P gradient - Cellular sources and biological significance

Timothy Hla et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)