相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Mitophagy, a Form of Selective Autophagy, Plays an Essential Role in Mitochondrial Dynamics of Parkinson's Disease
Xiao-Le Wang et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2022)
Inhibition of LRRK2 restores parkin-mediated mitophagy and attenuates intervertebral disc degeneration
Jialiang Lin et al.
OSTEOARTHRITIS AND CARTILAGE (2021)
Infection and Risk of Parkinson's Disease
Richard J. Smeyne et al.
JOURNAL OF PARKINSONS DISEASE (2021)
The genetic architecture of Parkinson's disease
Cornelis Blauwendraat et al.
LANCET NEUROLOGY (2020)
LRRK2 regulates endoplasmic reticulum-mitochondrial tethering through the PERK-mediated ubiquitination pathway
Toshihiko Toyofuku et al.
EMBO JOURNAL (2020)
Leucine-rich repeat kinase-2 (LRRK2) modulates microglial phenotype and dopaminergic neurodegeneration
Zach Dwyer et al.
NEUROBIOLOGY OF AGING (2020)
Characterization of Recessive Parkinson Disease in a Large Multicenter Study
Suzanne Lesage et al.
ANNALS OF NEUROLOGY (2020)
LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?
Tiago Fleming Outeiro et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2019)
SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy
Tatsuya Yamada et al.
AUTOPHAGY (2019)
Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice
Diana Matheoud et al.
NATURE (2019)
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease
Sangjune Kim et al.
NEURON (2019)
Leucine-Rich Repeat Kinase 2 Is Associated With Activation of the Paraventricular Nucleus of the Hypothalamus and Stress-Related Gastrointestinal Dysmotility
Tatsunori Maekawa et al.
FRONTIERS IN NEUROSCIENCE (2019)
Impact of Dopamine Oxidation on Dopaminergic Neurodegeneration
Shun Zhang et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
Benjamin H. M. Hunn et al.
CELL REPORTS (2019)
The unlikely partnership between LRRK2 and α-synuclein in Parkinson's disease
Noemie Cresto et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2019)
Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies
Xiaoguang Liu et al.
HUMAN MOLECULAR GENETICS (2019)
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion
Ruoxi Wang et al.
JOURNAL OF CELL BIOLOGY (2019)
Reducing Mcl-1 gene dosage induces dopaminergic neuronal loss and motor impairments in Park2 knockout mice
Susanna Ekholm-Reed et al.
COMMUNICATIONS BIOLOGY (2019)
Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis
Divya Bhatia et al.
JCI INSIGHT (2019)
Reduced cerebral vascularization in experimental neuronopathic Gaucher disease
Nicholas J. C. Smith et al.
JOURNAL OF PATHOLOGY (2018)
The genetics of Parkinson disease
Hao Deng et al.
AGEING RESEARCH REVIEWS (2018)
Loss of Parkin impairs mitochondrial function and leads to muscle atrophy
Nesibe Peker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2018)
Characterization of early-onset motor deficits in the Pink1-/- mouse model of Parkinson disease
Cynthia A. Kelm-Nelson et al.
BRAIN RESEARCH (2018)
Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting
Erin T. Williams et al.
HUMAN MOLECULAR GENETICS (2018)
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
Laura Pellegrini et al.
HUMAN MOLECULAR GENETICS (2018)
Increased oxidative stress and coenzyme Q10 deficiency in centenarians
Midori Nagase et al.
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2018)
Partial loss of ATP13A2 causes selective gliosis independent of robust lipofuscinosis
Sruti Rayaprolu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2018)
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
Chao Peng et al.
NATURE (2018)
Parkin absence accelerates microtubule aging in dopaminergic neurons
Daniele Cartelli et al.
NEUROBIOLOGY OF AGING (2018)
Adenosine A2A Receptor Antagonists in Neurodegenerative Diseases: Huge Potential and Huge Challenges
Rafael Franco et al.
FRONTIERS IN PSYCHIATRY (2018)
Parkin and PINK1 mitigate STING-induced inflammation
Danielle A. Sliter et al.
NATURE (2018)
The genetic landscape of Parkinson's disease
A. Lunati et al.
REVUE NEUROLOGIQUE (2018)
Parkinson's Disease: Biomarkers, Treatment, and Risk Factors
Fatemeh N. Emamzadeh et al.
FRONTIERS IN NEUROSCIENCE (2018)
Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation
Komudi Singh et al.
GLIA (2018)
Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells
Guoxiang Jin et al.
NATURE IMMUNOLOGY (2018)
Epidemiology of Parkinson's Disease-East Versus West
Masoom M. Abbas et al.
MOVEMENT DISORDERS CLINICAL PRACTICE (2018)
Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells
Haifang Wang et al.
JOURNAL OF IMMUNOLOGY (2017)
Parkinson disease-associated LRRK2 G2019S transgene disrupts marrow myelopoiesis and peripheral Th17 response
Jeongho Park et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2017)
PINK1 regulates mitochodrial trafficking in dentrites of cortical neurons therough mitochondrial PKA
Tania Das Banerjee et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Caffeine, creatine, GRIN2A and Parkinson's disease progression
David K. Simon et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2017)
Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination
Hiroyuki Kabayama et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2017)
Health benefits of methylxanthines in neurodegenerative diseases
Ainhoa Onatibia-Astibia et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2017)
Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism
Lanying Song et al.
NEUROBIOLOGY OF DISEASE (2017)
Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions
Mei-Yao Lin et al.
NEURON (2017)
Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice
Emilie Giaime et al.
NEURON (2017)
TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease
Seong Su Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Synucleins Have Multiple Effects on Presynaptic Architecture
Karina J. Vargas et al.
CELL REPORTS (2017)
Synucleins and Gene Expression: Ramblers in a Crowd or Cops Regulating Traffic?
Alexei A. Surguchev et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice
Robert S. Rogers et al.
FRONTIERS IN NEUROSCIENCE (2017)
Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function
Chul Ju Hwang et al.
REDOX BIOLOGY (2017)
Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons
Divya Pathak et al.
ENEURO (2017)
New Genes Causing Hereditary Parkinson's Disease or Parkinsonism
Andreas Puschmann
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2017)
The ratio of oxidized and reduced forms of selected antioxidants as a possible marker of oxidative stress in humans
Roman Kand'ar
BIOMEDICAL CHROMATOGRAPHY (2016)
LRRK2 deficiency impacts ceramide metabolism in brain
Ruggero Ferrazza et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation
Diana Matheoud et al.
CELL (2016)
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study
Tomoteru Yamasaki et al.
JOURNAL OF NEUROSCIENCE (2016)
The epidemiology of Parkinson's disease: risk factors and prevention
Alberto Ascherio et al.
LANCET NEUROLOGY (2016)
Epidemiology of Parkinson's disease
A. Elbaz et al.
REVUE NEUROLOGIQUE (2016)
Abnormal Development of Glutamatergic Synapses Afferent to Dopaminergic Neurons of the Pink1-/- Mouse Model of Parkinson's Disease
Edouard Pearlstein et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
Rita Valenzuela et al.
CELL DEATH & DISEASE (2016)
Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis
Georg Auburger et al.
PARKINSONS DISEASE (2016)
Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression
Anastasia G. Henry et al.
HUMAN MOLECULAR GENETICS (2015)
Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration
Joao P. L. Daher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
A53T Human α-Synuclein Overexpression in Transgenic Mice Induces Pervasive Mitochondria Macroautophagy Defects Preceding Dopamine Neuron Degeneration
Linan Chen et al.
JOURNAL OF NEUROSCIENCE (2015)
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
Alicia M. Pickrell et al.
NEURON (2015)
Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression
Suzana Gispert et al.
HUMAN MOLECULAR GENETICS (2015)
LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory
Dayne A. Beccano-Kelly et al.
HUMAN MOLECULAR GENETICS (2015)
PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
Dieter A. Kubli et al.
PLOS ONE (2015)
Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes
Raffaele Renella et al.
AMERICAN JOURNAL OF HEMATOLOGY (2014)
α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling
Lina Wang et al.
CURRENT BIOLOGY (2014)
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export
Hyun Jin Cho et al.
EMBO JOURNAL (2014)
Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease
Hui Qi et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2014)
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
Ghazaleh Ashrafi et al.
JOURNAL OF CELL BIOLOGY (2014)
Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis
Karina J. Vargas et al.
JOURNAL OF NEUROSCIENCE (2014)
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
Loukia Parisiadou et al.
NATURE NEUROSCIENCE (2014)
Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse
Tonya N. Taylor et al.
NEUROBIOLOGY OF DISEASE (2014)
Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress
Nicoleta Moisoi et al.
NEUROPHARMACOLOGY (2014)
Transgenic mice expressing S129 phosphorylation mutations in α-synuclein
Valerie Drews Escobar et al.
NEUROSCIENCE LETTERS (2014)
Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
Dayne A. Beccano-Kelly et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment
Jason R. Cannon et al.
EXPERIMENTAL NEUROLOGY (2013)
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited -synuclein accumulation and age-dependent sensorimotor deficits
Patrick J. Schultheis et al.
HUMAN MOLECULAR GENETICS (2013)
Accumulation of the parkin substrate, FAF1, plays a key role in the dopaminergic neurodegeneration
Jee-Won Sul et al.
HUMAN MOLECULAR GENETICS (2013)
Caffeine Consumption Prevents Memory Impairment, Neuronal Damage, and Adenosine A2A Receptors Upregulation in the Hippocampus of a Rat Model of Sporadic Dementia
Janaina Espinosa et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction
Dieter A. Kubli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis
Weirong Xing et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
Parkin-Dependent Degradation of the F-Box Protein Fbw7β Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1
Susanna Ekholm-Reed et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
Victoria S. Burchell et al.
NATURE NEUROSCIENCE (2013)
100 years of Lewy pathology
Michel Goedert et al.
NATURE REVIEWS NEUROLOGY (2013)
α-Synucleinopathy phenotypes
Heather McCann et al.
PARKINSONISM & RELATED DISORDERS (2013)
Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein
Simon M. L. Paine et al.
PLOS ONE (2013)
Short- and Long-Term Effects of LRRK2 on Axon and Dendrite Growth
Bryan Sepulveda et al.
PLOS ONE (2013)
Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein
Theodore A. Sarafian et al.
PLOS ONE (2013)
Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model
Stephanie Janezic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cigarette smoking, coffee intake and alcohol consumption preceding Parkinson's disease: a case-control study
Sandra B. Sipetic et al.
ACTA NEUROPSYCHIATRICA (2012)
Caffeine Intake, Smoking, and Risk of Parkinson Disease in Men and Women
Rui Liu et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2012)
α-Synuclein knockout mice have cognitive impairments
V. S. Kokhan et al.
BEHAVIOURAL BRAIN RESEARCH (2012)
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes
Karly C. Sourris et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Deletion of alpha-synuclein decreases impulsivity in mice
Y. Pena-Oliver et al.
GENES BRAIN AND BEHAVIOR (2012)
Inactivation of Pink1 Gene in Vivo Sensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes, Parkin or DJ-1
M. Emdadul Haque et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
L-DOPA Impairs Proteasome Activity in Parkinsonism through D1 Dopamine Receptor
Amandine Berthet et al.
JOURNAL OF NEUROSCIENCE (2012)
In Vivo Alterations in Calcium Buffering Capacity in Transgenic Mouse Model of Synucleinopathy
Lidia Reznichenko et al.
JOURNAL OF NEUROSCIENCE (2012)
α-Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis
David Scott et al.
JOURNAL OF NEUROSCIENCE (2012)
Mitochondrial CB1 receptors regulate neuronal energy metabolism
Giovanni Benard et al.
NATURE NEUROSCIENCE (2012)
ABERRANT STRIATAL SYNAPTIC PLASTICITY IN MONOGENIC PARKINSONISMS
G. Madeo et al.
NEUROSCIENCE (2012)
Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1
Derya R. Shimshek et al.
SCIENTIFIC REPORTS (2012)
Dopamine Oxidation and Autophagy
Patricia Munoz et al.
PARKINSONS DISEASE (2012)
Decreased reuptake of dopamine in the dorsal striatum in the absence of alpha-synuclein
Heramb Chadchankar et al.
BRAIN RESEARCH (2011)
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
Kye-Young Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family
Sabina Anwar et al.
JOURNAL OF NEUROSCIENCE (2011)
ALTERED PROFILE AND D2-DOPAMINE RECEPTOR MODULATION OF HIGH VOLTAGE-ACTIVATED CALCIUM CURRENT IN STRIATAL MEDIUM SPINY NEURONS FROM ANIMAL MODELS OF PARKINSON'S DISEASE
G. Martella et al.
NEUROSCIENCE (2011)
Neuromuscular pathology in mice lacking alpha-synuclein
Anssi Pelkonen et al.
NEUROSCIENCE LETTERS (2011)
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
Filio Billia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes
Emelie Braschi et al.
CURRENT BIOLOGY (2010)
Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes
Yien-Ming Kuo et al.
HUMAN MOLECULAR GENETICS (2010)
Caffeine as a Protective Factor in Dementia and Alzheimer's Disease
Marjo H. Eskelinen et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Caffeine and Adenosine
Joaquim A. Ribeiro et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain
Heike Siebert et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice
Abdelmojib Al-Wandi et al.
NEUROBIOLOGY OF AGING (2010)
Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by α-synuclein
Marife Cano-Jaimez et al.
NEUROBIOLOGY OF DISEASE (2010)
Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
Venu M. Nemani et al.
NEURON (2010)
A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice
Alexander Kurz et al.
PLOS ONE (2010)
αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction
Becket Greten-Harrison et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
Youren Tong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Meeting Report: Consensus Statement-Parkinson's Disease and the Environment: Collaborative on Health and the Environment and Parkinson's Action Network (CHE PAN) Conference 26-28 June 2007
Jeff Bronstein et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2009)
Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin
G. Martella et al.
EXPERIMENTAL NEUROLOGY (2009)
Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study
Marjo H. Eskelinen et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Impaired dopamine release and synaptic plasticity in the striatum of Parkin-/- mice
Tohru Kitada et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
Loukia Parisiadou et al.
JOURNAL OF NEUROSCIENCE (2009)
Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by β-Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway
Paula M. Canas et al.
JOURNAL OF NEUROSCIENCE (2009)
Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration
Suzana Gispert et al.
PLOS ONE (2009)
The MitoPark Mouse - An animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons
Mats Ekstrand et al.
PARKINSONISM & RELATED DISORDERS (2009)
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers
Margaret Neuspiel et al.
CURRENT BIOLOGY (2008)
Neuroinflammation and oxidation/nitration of α-synuclein linked to dopaminergic neurodegeneration
Hui-Ming Gao et al.
JOURNAL OF NEUROSCIENCE (2008)
Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
Tamy C. Frank-Cannon et al.
JOURNAL OF NEUROSCIENCE (2008)
Essential role of cyclin-G-associated kinase (auxilin-2) in developing and mature mice
Dong-won Lee et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Caffeine, adenosine receptors, memory and Alzheimer disease
Rodrigo A. Cunha
MEDICINA CLINICA (2008)
Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking
Christopher P. Toret et al.
TRAFFIC (2008)
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
Nicole Exner et al.
JOURNAL OF NEUROSCIENCE (2007)
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
Tohru Kitada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
P Klivenyi et al.
NEUROBIOLOGY OF DISEASE (2006)
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
WW Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking α-synuclein
CE Ellis et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
α-Synuclein gene deletion decreases brain palmitate uptake and alters the palmitate metabolism in the absence of α-synuclein palmitate binding
MY Golovko et al.
BIOCHEMISTRY (2005)
Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background
DE Cabin et al.
NEUROBIOLOGY OF AGING (2005)
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
DJ Moore et al.
HUMAN MOLECULAR GENETICS (2005)
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
JJ Palacino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Levodopa in the treatment of Parkinson's disease: Current controversies
CW Olanow et al.
MOVEMENT DISORDERS (2004)
α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines
B Martín-Clemente et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Surgical treatment for Parkinson's disease
BL Walter et al.
LANCET NEUROLOGY (2004)
Altered fatty acid composition of dopaminergic neurons expressing α-synuclein and human brains with α-synucleinopathies
R Sharon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
MS Goldberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
S Gispert et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
Autosomal recessive early onset parkinsonism is linked to three loci: PARK2, PARK6, and PARK7
V Bonifati et al.
NEUROLOGICAL SCIENCES (2002)
Risk factors for Alzheimer's disease:: A prospective analysis from the Canadian Study of Health and Aging
J Lindsay et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2002)
Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease
GW Ross et al.
DRUGS & AGING (2001)
A yeast DNA J protein required for uncoating of clathrin-coated vesicles in vivo
B Pishvaee et al.
NATURE CELL BIOLOGY (2000)
Spectrum of Parkinson's disease, Parkinson's dementia, and lewy body dementia
IG McKeith et al.
NEUROLOGIC CLINICS (2000)
Association of coffee and caffeine intake with the risk of Parkinson disease
GW Ross et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)
分享论文
